Ursus maritimus (polar bear): 103671905
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Entry
103671905 CDS
T03271
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr05200
Pathways in cancer
umr05223
Non-small cell lung cancer
umr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103671905 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103671905 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
103671905 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103671905 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
umr04090
]
103671905 (ALK)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103671905 (ALK)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
ALK family
103671905 (ALK)
CD molecules [BR:
umr04090
]
Proteins
103671905 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
103671905
NCBI-ProteinID:
XP_008698783
UniProt:
A0A384CVH5
LinkDB
All DBs
Position
Unknown
AA seq
1624 aa
AA seq
DB search
MGSLGLLGLLLPLLSVAASGSGTGTGTETGTETGQLVSSPALGPALQPREPLSYSRLQRK
SLAVDFVVPSLFRVYARDLLLPPSSSLEPRAGRTEVHGSLALDCAPLLRLVGPPPWVSWT
ESASSPAPVQARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEATVGLLQFN
LSELFSWWIRHGEGRLRIRLMPEKKASEVGREGKLSAAIRASQPRLLFQILGTGRSSLES
PTSLPSPPPEPFAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLGNQSWS
WRRVPSEEASQMDLLDGPETEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEHCRLAV
SVHRHLQPSGRYVAQLLPHNEPGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISS
GNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHRDCAQGEDEGQ
LCSKLPAGFYCNFEDGFCGWTQGTLAPHNPRWQIRTLKDARGQDHRGHALLLSTTDVPTS
ESATVTSATFPAPMKNSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVATNEG
LSLWQWTVLPLVDVADRFWLQIVAWWGPGSRATVAFDNISISLDCYLTISGEDKMPQNTA
PKSRNLFERNPNKEPKVWENTRETPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNSNL
SVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKGDM
LYILVGQQGEDACPSTNRLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM
KDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLL
WSGKSLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEI
DGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEGDECHMDPESHKVICFCDH
GTVLADDGVSCIVSPTPEPHLPLSLVLSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQ
MELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEV
YEGQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQAL
PRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDI
AARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKT
DTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQP
EDRPNFAIILERIEYCTQDPDVIHTALPVEYGPLVEEEEKVPVRPQDPEGIPPLLVSPPQ
ANREEGREPAAPPPLPSASSGRAVKKPAAAEPSVRGARAPAVEGGHVNMAFSQSNPPSEL
HKVQGSRNKPTSLWNPTYGSWFTEKPARKTNPPAKKERHERGTPGREGSCAVAPPAAGGP
LPGASVLLEPSSLTASVKEVPLFRLRHFPCGTVNYGYQQQGLPLEAAAGAGRYGDSLLKS
RPAP
NT seq
4875 nt
NT seq
+upstream
nt +downstream
nt
atgggatcgttagggctcctagggctgctgctgccgctgctttcagtggcagcctcgggc
tccgggaccgggacagggacagagaccgggactgagactggccagctcgtgagctcaccc
gccctggggccggctctgcagcctcgggagccgctcagctactcacgtctgcagaggaag
agcctggcggtggactttgtggtgccctcgctcttccgcgtctatgcccgggacctgctg
ctgccgccttcgtcctcgttggagccgagggctggccggacggaggtgcatggctcgctg
gctctagactgcgccccactacttcggctggtggggccaccgccctgggtctcctggaca
gaaagcgccagctcgccagccccggtccaggcacggacgctgaccagggtgctgaagggc
ggctcggttcgcaagctccggcgcgccaagcagctggtgctggagctgggagaggaggct
atccttgaggggtgcgtcgggcccccagaggaggcaactgtgggactgctccagttcaac
cttagcgagctgttcagctggtggattcgccatggcgaggggcggctgaggatccgcctg
atgccggagaagaaggcttcggaagtgggcagagagggaaagctgtccgcggcgatccgc
gcctcccagccccgccttctcttccagatcttggggaccggtcgcagctccttggagtca
ccgacaagcctgccttctcctcctcctgagcctttcgcatggaatctgacgtggataatg
aaagattccttccctttcctctctcatcgtagtcgatatggcctggagtgcagcttcgat
ttcccctgcgagctggagtactccccgccccttcacgaccttggcaaccagagctggtcc
tggcgccgcgtcccctctgaggaggcctcccagatggacctgttggatgggccggagaca
gagcactccaaggagatgccccgaggctccttcctcctcctcaacacctcagccaactcc
aagcacaccatcctgagtccgtggatgaggagcagcagtgagcactgcaggctggctgtc
tccgtgcacaggcatctacagccttctgggaggtatgtcgcccagctgctgccccacaac
gagcctggaagagagatcctcctggtacctaccccaggaaagcatggatggacagtgctt
cagggaagaattgggcgcccagagaatcccttccgagtggccctggaatacatctcaagt
ggaaaccgaagcttgtctgcagtggacttctttgccctgaaaaactgcagcgaaggaaca
tccccgggctccaagatggctttgcagagttccttcacctgctggaacgggaccgtcctc
cagctcgggcaggcctgtgacttccaccgggactgcgcccagggagaagacgagggccag
ctgtgcagtaagctccctgctggtttttactgcaacttcgaggatggcttctgtggctgg
acccagggcacactcgcaccccacaacccccggtggcagatcaggaccctgaaggatgcc
cggggccaggaccaccgaggccacgccctattgctcagcaccactgacgtccctacttct
gaaagtgctactgtgaccagcgctacgttccccgccccgatgaagaactctccgtgtgag
ctccgaatgtcctggctcatccgtggagtcttgcggggaaatgtctccttggtgctagtg
gagaacaaaactgggaaggaacaaggcagaatggtctggcatgttgccaccaatgaaggc
ttgagcctgtggcagtggacggtgctgcctcttgtcgatgtggctgacaggttctggctg
cagattgttgcgtggtggggcccaggatccagagccaccgtggcttttgacaatatctcc
atcagcctggactgctacctcaccatcagcggagaggacaagatgccacagaatacagcc
cccaaatcaagaaatctatttgagagaaacccaaacaaggagccaaaagtctgggaaaac
acaagagagacccccatctttgaccccacagttcactggctgttcaccacgtgcggggcc
agcgggccccatggccccacacaggcccagtgtaacaacgcctaccggaattccaacctg
agcgtggtggtggggagcgagggccccctgaaaggcatccagacctggaaggtgccagcc
accgacacctacagcatctcaggctacggagctgctggtgggaaaggcgggaagaacacc
atgatgcggtcccacggcgtgtctgtgctgggcatcttcaacctggagaagggcgacatg
ctgtatatcctagttggacaacagggggaagacgcctgccccagcacaaaccgattaatc
cagaaagtgtgcattggtgagaacaacgtgatagaagaagagatccgtgtgaacaggagt
gtgcatgagtgggcaggagggggtggaggtggaggcggagccacgtacgtgtttaagatg
aaggatggcgtgccagtgcccctgatcattgcagccggcggtggcggcagggcctatggg
gccaagacagacacgttccacccagagagactggagaataactcctcggttctggggctg
aacggcaactctggagccgcaggtggcggaggtggctggaatgataacacttccttgctc
tggtctggaaagtctttgctggagggtgccaccggaggacattcctgcccccaggccatg
aagaagtgggggtgggagacaagagggggtttcggagggggtggaggggggtgctcctca
ggtggaggaggcggaggatatataggcggcaacgcggcctcaaacaatgaccccgagatc
gacggggaggacggggtctctttcatcagtccgctgggcatcctgtatacccccgcttta
aaagtgatggagggccatggggaagtgaatattaagcattatctgaactgcagccactgt
gagggagacgagtgccacatggaccccgagagccacaaggtcatctgcttctgtgaccac
gggacagtgctggctgacgatggcgtctcctgcattgtgtcccccaccccagagccccac
ctgccgctctcgctggtcctgtctgtcgtgacctcagccctcgtggccgccctggtcctg
gctttctccggcatcatgattgtgtaccgccggaagcaccaggagctgcaagccatgcag
atggagctgcagagccctgagtacaagctgagcaagctccgcacctcgaccatcatgacc
gactacaaccccaactactgcttcgctggcaagacctcgtccatcagcgacctgaaggag
gtgcctcggaaaaacatcaccctcatccggggactgggccacggtgcattcggggaggtg
tatgaaggtcaggtgtccggagtgcccagcgacccgagccccctgcaagtggctgtaaag
acgctgcctgaagtgtgttctgaacaggacgaactggatttcctcatggaagccctgata
atcagcaaattcaaccaccagaacatcgtgcgctgtattggggtgagtctgcaagccctg
ccccgatttatcctgctggagctcatggcaggaggagacctcaagtccttcctccgggag
acccgccctcgcccgaaccagccctcctccctggccatgctggaccttctgcacgtggct
cgggacatcgcctgtggctgtcagtatttggaggaaaatcacttcatccaccgagacatt
gctgccagaaactgcctcttgacctgtccgggccctggcagagtggccaagattggagac
tttggaatggcccgggacatctacagagcgagctactaccgaaaaggaggctgcgccatg
ctgcccgtcaaatggatgcctccagaggccttcatggaagggatattcacttctaaaacg
gacacatggtccttcggcgtgctgctgtgggaaatattttctcttggatacatgccgtac
cccagcaaaagcaaccaagaagttctggagttcgtcaccagcggaggacggatggaccca
cctaagaactgccctgggcccgtataccggataatgacccagtgctggcaacatcagcct
gaagacaggcccaactttgccataattttggagaggatcgaatactgcacccaggacccg
gatgtgatccacacggctctgcccgtagagtacggcccgctggtggaggaggaggagaag
gtgcccgtgaggccccaagacccggaggggatcccgccgctcctcgtctctcccccccag
gctaaccgcgaggaggggcgcgagccggctgccccgccgcccctgccttccgcgtcctcc
ggcagagccgtgaagaagcccgcggcggccgagccgtctgttcgaggcgcgcgggcgccg
gccgtggaaggaggacacgtgaacatggcgttctcccagtccaacccgccttcagagctg
cacaaggtccagggatccaggaacaagccgaccagcctgtggaaccccacgtacggctcg
tggtttacggagaaacccgccagaaagaccaatcctccagccaagaaggagcgccacgag
aggggcaccccggggcgggaggggagctgtgctgtcgcccctcccgcggcgggcggcccg
ctgccgggagcgtctgtgctgctggagccgtcctcgctgacggccagcgtgaaggaggtg
cccctgttccggctgcgccacttcccgtgcggcaccgtcaactacggctaccagcagcag
ggcctgccgctggaggccgccgccggggccgggcgctacggggacagcctgctgaagagc
cggcccgcgccctga
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integrated database retrieval system
