Ursus maritimus (polar bear): 103673473 Help Entry 103673473         CDS       T03271                                  Symbol THBS1 Name (RefSeq) thrombospondin-1   KO K16857   thrombospondin 1 Organism umr  Ursus maritimus (polar bear) Pathway umr04015   Rap1 signaling pathway umr04115   p53 signaling pathway umr04145   Phagosome umr04148   Efferocytosis umr04151   PI3K-Akt signaling pathway umr04350   TGF-beta signaling pathway umr04510   Focal adhesion umr04512   ECM-receptor interaction umr04820   Cytoskeleton in muscle cells umr05144   Malaria umr05165   Human papillomavirus infection umr05205   Proteoglycans in cancer umr05206   MicroRNAs in cancer umr05219   Bladder cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103673473 (THBS1)    04350 TGF-beta signaling pathway     103673473 (THBS1)    04151 PI3K-Akt signaling pathway     103673473 (THBS1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     103673473 (THBS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     103673473 (THBS1)    04148 Efferocytosis     103673473 (THBS1)   09143 Cell growth and death    04115 p53 signaling pathway     103673473 (THBS1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103673473 (THBS1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     103673473 (THBS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     103673473 (THBS1)    05205 Proteoglycans in cancer     103673473 (THBS1)   09162 Cancer: specific types    05219 Bladder cancer     103673473 (THBS1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     103673473 (THBS1)   09174 Infectious disease: parasitic    05144 Malaria     103673473 (THBS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103673473 (THBS1)   09183 Protein families: signaling and cellular processes    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103673473 (THBS1) Membrane trafficking [BR:umr04131]  Endocytosis   Phagocytosis    Opsonins     103673473 (THBS1) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Extracellular matrix molecules    103673473 (THBS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TSP_C TSP_3 TSP_1 TSP1_spondin VWC TSP1_CFP_C EGF_3 cEGF EGF_CA TSP1_ADAMTS Laminin_G_3 TSP1_CCN Laminin_G_2 EGF Motif Other DBs NCBI-GeneID:  103673473 NCBI-ProteinID:  XP_008700482 UniProt:  A0A384D075 LinkDB All DBs Position Unknown AA seq 1170 aa AA seqDB search MGLAWGLSVLFLLHACGSSRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAIERKDHSGQVFSVV SNGKAGTLDLSLTVQGMQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSIFTRDLASVARLRVAKGGVNDHFQGVLQNVRFVFGTTPEAILRNKGCSSSTNVLL TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELAIELRRPPLCYHNGVQYRNNEEWTVDSCTECRCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE TKACKKDACPINGGWGPWSLWDLCSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDATEKQI CNKQDCPIDGCLSNPCFAGVKCTSYADGSWKCGACPPGYSGNGVQCEDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGPQPFGRGVDYATANKQVCKPRNPCTDGTHDCNKN AKCSYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLVCVANATYHCKKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENIDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDS NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt atggggctggcctggggactcagtgtcctattcctgttgcatgcgtgtggttccagccgc attccagagtctgggggagacaacagcgtgttcgacatctttgaactcaccggggctgcc cgtaagggctctgggcgccgactggtgaagggtcctgacccttccagcccagctttccgc atcgaggatgccaacctgattccccctgtgcctgatgacaagttccaagacctagtggat gccgtccgggcagagaaaggcttccttctcttggcctccctgaggcagatgaagaagacc cgaggcactctgctggccatagaacggaaagaccactcgggccaggtcttcagtgtggtc tccaatggcaaagcgggcaccctggacctgagcctcaccgtgcaggggatgcagcatgtg gtgtcggtggaggaggcgctcctggccaccggccagtggaagagcatcaccctgttcgtg caggaggaccgggcgcagctgtacatcgactgtgagaagatggagaacgcagagctggat gtccccatccagagcatcttcaccagggacctggccagtgtggccagactccgcgttgcc aaaggaggggtcaatgaccatttccagggggtgctgcagaacgtgaggtttgtcttcgga accacaccagaagccatcctcaggaacaaaggctgctccagctcgaccaatgtccttctc accctggacaacaatgtggtaaacggctccagccctgccatccgcactaactacattggc cacaagacgaaggatctgcaagccatctgcggcatctcttgtgacgagctgtccagcatg gtcctggagttgagaggcctgcgcaccattgtcaccacactccaggacagcattcgcaaa gtgactgaagagaacaaagagttggccattgagctgaggaggcctccgctctgctaccac aacggagttcagtacaggaataatgaggaatggactgttgatagctgcacggagtgccgc tgtcagaactccgttaccatctgtaagaaagtgtcctgccccatcatgccctgctccaac gccacagtccccgatggagaatgctgcccacggtgttggcccagcgactctgcggatgat ggctggtccccgtggtccgagtggacctcctgctctgcaacctgtggcaatggaatccag cagcgcggtcgctcctgtgacagtctcaacaaccgatgcgagggctcctccgtccagacg cggacctgccacattcaggaatgcgataagagatttaaacaggatggtggctggagccac tggtccccgtggtcatcttgttccgtgacctgcggcgatggtgtgatcacaagaattcga ctctgcaattctccgagcccccagatgaacgggaaaccatgtgaaggcgaagcccgcgag accaaagcctgcaagaaagacgcctgccccatcaacggaggctggggtccctggtcgctg tgggacctctgctctgtcacctgcggaggaggggtgcagagacgtagccggctctgcaac aaccccacaccccagtttggaggcaaggactgtgtcggtgacgcgacagaaaaacagatc tgcaacaagcaggactgtccaattgacggatgcctgtccaatccctgctttgctggggtc aagtgtacgagttacgcagatggcagctggaaatgcggtgcctgtcccccgggctacagc ggaaacggcgtccagtgcgaagacgtggatgagtgcaaagaagtacccgacgcctgcttc aaccacaacggcgagcacaggtgtgagaacaccgaccccggctacaactgcctgccctgc ccgcctcgcttcacgggcccgcagcccttcggccggggtgtggactacgccactgccaac aaacaggtgtgcaagccgcgcaacccctgcacggacgggacgcacgactgcaacaagaac gccaagtgcagctacctgggccactacagcgaccccatgtaccgctgcgagtgcaagccc ggctacgcgggcaacggcatcatctgcggggaggacacagacctggatggatggcccaac gaggacctggtgtgcgtggccaatgccacctaccactgcaaaaaggataactgtcccaac ctgccaaactccgggcaggaggactacgacaaggatggaatcggcgacgcctgtgatgac gacgatgacaacgataaaatcccggacgacagggacaactgcccattccattacaaccca gcccagtatgactacgaccgagatgatgtgggagaccgctgtgacaactgcccctacaac cacaaccccgatcaggctgacacggacaacaacggggaaggagacgcctgcgccgcagac atcgatggggacggtatcctcaatgaacgagacaactgccaatatgtctacaacgtggac cagagggacacagatatggatggggttggagatcagtgtgacaactgccccctggaacac aatccagatcagctcgactctgactcagaccgcattggagacacgtgtgacaacaatcag gatattgatgaagacggccaccagaacaacctggacaactgtccctatgtgcccaatgcc aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccatgatgatgacaat gacggcattcctgatgacagggacaactgccgactcgtgcccaaccctgaccagaaggat tctgatggtgatggtcgaggtgatgcctgcaaagacgattttgaccatgacaatgtgcca gacattgatgacatctgtcctgaaaacattgatatcagcgagactgatttccgccgattc cagatgattcctctagatcccaaagggacatcccagaatgaccctaactgggtcgtacgc catcagggtaaagaactcgtccagaccgtcaactgtgatcctggacttgctgtaggttac gatgagtttaatgccgtggacttcagtggcaccttcttcatcaacacggaaagggatgac gactatgctggatttgtgttcggctaccagtctagcagccgcttttatgttgttatgtgg aagcaagtcacccaatcctactgggacaccaaccccactagggctcagggatactcaggc ctttctgtgaaagttgtgaactcaaccaccgggccaggcgagcacctgcggaatgccctg tggcacacgggaaacacccctggccaggttcgtactctgtggcatgaccctcgtcacata ggttggaaagatttcactgcctacagatggcgtctcagccaccggcccaagacgggtttc attagagtggtgatgtacgaagggaagaaaatcatggctgactcaggacccatctatgac aaaacctatgctggtggtaggctagggttgtttgtcttctcgcaagaaatggtgttcttc tccgacctgaaatacgaatgcagagattcctaa

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