KEGG   Ursus maritimus (polar bear): 103675245
Entry
103675245         CDS       T03271                                 
Symbol
TRAF2
Name
(RefSeq) TNF receptor-associated factor 2 isoform X1
  KO
K03173  TNF receptor-associated factor 2 [EC:2.3.2.27]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04064  NF-kappa B signaling pathway
umr04071  Sphingolipid signaling pathway
umr04137  Mitophagy - animal
umr04141  Protein processing in endoplasmic reticulum
umr04210  Apoptosis
umr04217  Necroptosis
umr04380  Osteoclast differentiation
umr04621  NOD-like receptor signaling pathway
umr04622  RIG-I-like receptor signaling pathway
umr04657  IL-17 signaling pathway
umr04668  TNF signaling pathway
umr04920  Adipocytokine signaling pathway
umr04932  Non-alcoholic fatty liver disease
umr05010  Alzheimer disease
umr05014  Amyotrophic lateral sclerosis
umr05016  Huntington disease
umr05017  Spinocerebellar ataxia
umr05022  Pathways of neurodegeneration - multiple diseases
umr05132  Salmonella infection
umr05135  Yersinia infection
umr05160  Hepatitis C
umr05163  Human cytomegalovirus infection
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05168  Herpes simplex virus 1 infection
umr05169  Epstein-Barr virus infection
umr05170  Human immunodeficiency virus 1 infection
umr05200  Pathways in cancer
umr05203  Viral carcinogenesis
umr05222  Small cell lung cancer
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    103675245 (TRAF2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103675245 (TRAF2)
   04064 NF-kappa B signaling pathway
    103675245 (TRAF2)
   04668 TNF signaling pathway
    103675245 (TRAF2)
   04071 Sphingolipid signaling pathway
    103675245 (TRAF2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    103675245 (TRAF2)
  09143 Cell growth and death
   04210 Apoptosis
    103675245 (TRAF2)
   04217 Necroptosis
    103675245 (TRAF2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    103675245 (TRAF2)
   04622 RIG-I-like receptor signaling pathway
    103675245 (TRAF2)
   04657 IL-17 signaling pathway
    103675245 (TRAF2)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    103675245 (TRAF2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103675245 (TRAF2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103675245 (TRAF2)
   05203 Viral carcinogenesis
    103675245 (TRAF2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    103675245 (TRAF2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103675245 (TRAF2)
   05160 Hepatitis C
    103675245 (TRAF2)
   05168 Herpes simplex virus 1 infection
    103675245 (TRAF2)
   05163 Human cytomegalovirus infection
    103675245 (TRAF2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103675245 (TRAF2)
   05169 Epstein-Barr virus infection
    103675245 (TRAF2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103675245 (TRAF2)
   05135 Yersinia infection
    103675245 (TRAF2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103675245 (TRAF2)
   05014 Amyotrophic lateral sclerosis
    103675245 (TRAF2)
   05016 Huntington disease
    103675245 (TRAF2)
   05017 Spinocerebellar ataxia
    103675245 (TRAF2)
   05022 Pathways of neurodegeneration - multiple diseases
    103675245 (TRAF2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103675245 (TRAF2)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103675245 (TRAF2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:umr03019]
    103675245 (TRAF2)
   04121 Ubiquitin system [BR:umr04121]
    103675245 (TRAF2)
Enzymes [BR:umr01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     103675245 (TRAF2)
Messenger RNA biogenesis [BR:umr03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     103675245 (TRAF2)
Ubiquitin system [BR:umr04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    103675245 (TRAF2)
SSDB
Motif
Pfam: TRAF-mep_MATH MATH_2 TRAF_BIRC3_bd zf-TRAF TRAF2_zf zf-C3HC4 TRAF3_RING zf-C3HC4_2 zf-RING_6 zf-C3HC4_4 SlyX
Other DBs
NCBI-GeneID: 103675245
NCBI-ProteinID: XP_040488160
UniProt: A0A8M1G094
LinkDB
Position
Unknown
AA seq 535 aa
MPRARAWRFAALMAAASVTPPGSLDLLQPGFSKTLLGTKPEDKYLCSACKNVLRRPFQAQ
CGHRYCSYCLTSILSSGPQNCAACVQEGIYEEGVSILESGSAFPDNAARREVESLPAVCP
SDGCTWKGTLKEYESCHEGHCPFMLTECPACKGLVRLGEKERHSEQECPERSLSCRHCRA
PCCWADLKAHHEVCPKFPLTCDGCGKKKISREKFQDHVRACGKCRVPCRFHIVGCPEMVE
SEKQQQHEAQWLREHLGMLLGGLLETKPLSGAGGRFLGQSEVGGWEASTLHPEAELSKAA
ELRQRCEALERKTATFENIVCVLNREVERVAMTAEACGRQHRLDQDRIEALSNKVQQLER
SIGLKDLAMAELEQKVHEMEATTFDGVFIWKISDFARKRQEAVAGRTPAIFSPAFYTSRY
GYKMCLRIYLNGDGTGRGTHLSLFFVVMRGPNDALLRWPFNQKVTLMLLDQNNREHVIDA
FRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
NT seq 1608 nt   +upstreamnt  +downstreamnt
atgcccagggcaagggcgtggcggttcgcagctctcatggctgcagccagtgtgacccct
cccggctccctagatctgttgcagcctggcttctcgaagaccctcctggggaccaagccg
gaggacaagtatctgtgctcggcctgcaagaacgtcctgcgcaggcctttccaggctcag
tgtggccaccgctactgctcctactgtctgaccagcatcctgagctccgggcctcagaac
tgtgctgcctgtgttcaggagggcatatatgaggaaggcgtctcgattttggaaagtggt
tcggctttcccagacaacgctgcacgcagggaggtggagagcctgccagccgtctgtccc
agcgacggctgcacctggaaggggacccttaaagagtatgagagctgccatgaaggacac
tgcccgttcatgctgaccgagtgcccggcgtgcaaaggcctggttcgcctcggggagaag
gagcgtcactcggagcaggaatgcccggagagaagcctcagctgcaggcactgccgggcg
ccctgctgttgggcggacctgaaggcgcaccatgaggtctgccccaagttccccttgact
tgcgatggctgtggcaagaagaagatctcacgggagaaattccaggaccacgtcagggcg
tgcggcaagtgccgagtcccgtgcaggttccacattgtcggctgccccgagatggtggag
agcgagaagcagcagcagcatgaggcccagtggctccgggagcacttgggcatgctgctg
ggcggcctcctggagaccaagccactctcaggagcaggtggccgcttcctgggccagagc
gaagtggggggctgggaagccagcacgctgcaccctgaggcggagctctccaaggctgca
gagctccggcaacggtgtgaggccctggagaggaagacggccaccttcgagaacatcgtc
tgcgtcctgaaccgggaggtagagagggtggccatgaccgctgaggcctgcggccggcag
caccggctggaccaggacaggatcgaggccctgagtaacaaggtgcagcagctggagagg
agcatcggtctgaaggacctggcgatggctgagctggagcagaaggtccacgagatggag
gcgaccaccttcgatggtgtgttcatctggaagatatccgacttcgccaggaagcgtcag
gaagcggtggctggccgcacgcccgccatcttctccccagccttctacacgagcaggtac
ggctacaagatgtgtctgcgcatctacctgaacggggacggcaccggccgggggacacac
ctgtctctcttctttgtggtgatgaggggccccaacgacgcgctgctgcggtggcccttc
aaccagaaggtgaccttaatgctgcttgaccagaacaaccgggagcacgtgattgacgcc
ttcagacccgacgtgacctcgtcctctttccagaggccggtcagtgacatgaacatcgcc
agtggctgccccctcttttgccccgtctccaagatggaggccaagaattcctacgtgcgt
gacgacgccatcttcatcaaggccatagtggacctgacggggctctag

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