Ursus maritimus (polar bear): 103675706
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Entry
103675706 CDS
T03271
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04020
Calcium signaling pathway
umr04022
cGMP-PKG signaling pathway
umr04024
cAMP signaling pathway
umr04260
Cardiac muscle contraction
umr04261
Adrenergic signaling in cardiomyocytes
umr04270
Vascular smooth muscle contraction
umr04713
Circadian entrainment
umr04720
Long-term potentiation
umr04723
Retrograde endocannabinoid signaling
umr04724
Glutamatergic synapse
umr04725
Cholinergic synapse
umr04726
Serotonergic synapse
umr04727
GABAergic synapse
umr04728
Dopaminergic synapse
umr04742
Taste transduction
umr04911
Insulin secretion
umr04912
GnRH signaling pathway
umr04921
Oxytocin signaling pathway
umr04924
Renin secretion
umr04925
Aldosterone synthesis and secretion
umr04927
Cortisol synthesis and secretion
umr04929
GnRH secretion
umr04930
Type II diabetes mellitus
umr04934
Cushing syndrome
umr04935
Growth hormone synthesis, secretion and action
umr05010
Alzheimer disease
umr05020
Prion disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05031
Amphetamine addiction
umr05207
Chemical carcinogenesis - receptor activation
umr05410
Hypertrophic cardiomyopathy
umr05412
Arrhythmogenic right ventricular cardiomyopathy
umr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103675706 (CACNA1C)
04020 Calcium signaling pathway
103675706 (CACNA1C)
04024 cAMP signaling pathway
103675706 (CACNA1C)
04022 cGMP-PKG signaling pathway
103675706 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103675706 (CACNA1C)
04929 GnRH secretion
103675706 (CACNA1C)
04912 GnRH signaling pathway
103675706 (CACNA1C)
04921 Oxytocin signaling pathway
103675706 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
103675706 (CACNA1C)
04924 Renin secretion
103675706 (CACNA1C)
04925 Aldosterone synthesis and secretion
103675706 (CACNA1C)
04927 Cortisol synthesis and secretion
103675706 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
103675706 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
103675706 (CACNA1C)
04270 Vascular smooth muscle contraction
103675706 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
103675706 (CACNA1C)
04727 GABAergic synapse
103675706 (CACNA1C)
04725 Cholinergic synapse
103675706 (CACNA1C)
04728 Dopaminergic synapse
103675706 (CACNA1C)
04726 Serotonergic synapse
103675706 (CACNA1C)
04720 Long-term potentiation
103675706 (CACNA1C)
04723 Retrograde endocannabinoid signaling
103675706 (CACNA1C)
09157 Sensory system
04742 Taste transduction
103675706 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
103675706 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103675706 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
103675706 (CACNA1C)
05020 Prion disease
103675706 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
103675706 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
103675706 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103675706 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
103675706 (CACNA1C)
05414 Dilated cardiomyopathy
103675706 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103675706 (CACNA1C)
04934 Cushing syndrome
103675706 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
umr04040
]
103675706 (CACNA1C)
Ion channels [BR:
umr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103675706 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Etmic-2
Motif
Other DBs
NCBI-GeneID:
103675706
NCBI-ProteinID:
XP_040497917
UniProt:
A0A8M1GT01
LinkDB
All DBs
Position
Unknown
AA seq
2191 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTE
NVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLN
TLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVC
GGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLL
LFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM
AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKK
LARTASPEKKQEVVEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKCPY
PNPENTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIV
NDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNAD
YVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKIL
RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYT
CSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGW
PELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEY
KNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLA
MQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIID
VILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFR
LFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALND
TTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGS
SFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAK
GRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTA
LRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFR
KFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSA
ASEDDIFRRAGGLFGNHVTYYQSDGRSAFPQTFTTQRPLHINKAANSQGDTESPSHEKLV
DSTFTPSSYSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHGPPLSPAVRVQEAAW
KLSSKRCHSRESQIAMVCQEEVSQDETYDVKMSEDTEYCSEPSLISTEMLSYQDDENRQL
TPPEEDKRDVRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQA
LAVAGLSPLLQRSHSPSTFPRPCATPPATPGSRGWPPQPIPTLRLEGAESSEKLNSSFPS
IHCSSWSGEPTPCGAGSSAIRRARPVSLTVPSQAGARGRQFHGSASSLVEAVLISEGLGQ
FAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRA
GGQEGETCAAALACRKSEEELQDSRAHAGGL
NT seq
6576 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaacacgaggatgtacattccagaggaaaatcatcaaggttctaactat
gggagcccgcgcccagctcatgccaacatgaatgccaatgccgctgcggggctcgcccct
gagcacatccctacgccgggggcagccctgtcctggcaggcggctatcgacgcggcccgg
caggccaagctgatgggcagcgccggcaacgcgaccatctccacggtcagctccacgcag
cggaagcggcagcagtatgggaaacccaagaagcagggcagcacgactgccacgcgcccg
ccccgcgccctgctctgcctgactctgaagaaccccatccggagggcatgcatcagcatc
gtcgaatggaaatatcctttaccatttgaaataattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccctttccagaagacgactccaacgccaccaattcc
aacctggaacgagtggaatatctctttctcataatttttactgtggaagcatttttaaaa
gtaatagcctatggacttctctttcatcccaacgcttacctccgcaatggttggaattta
ctagattttataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaa
gctgacggggcaaatgctctgggagggaaaggagctggatttgacgtgaaggcactgagg
gcattccgcgtgctgcgccccttgcgcctggtatctggagtcccaagtctccaggtggtt
ctgaattccattatcaaggccatggtgcccctgctgcatattgctctgttagtgctgttt
gtaatcatcatctatgccatcattggcctggagctcttcatggggaagatgcataagacc
tgctacaaccaggagggcatagcagatgttccagcagaagatgatccttccccttgtgct
ctggagacaggccatgggcgtcagtgtcagaacggcactgtgtgcaagcctgggtgggac
gggcccaagcacggcatcaccaacttcgacaattttgccttcgccatgttgacagtgttc
cagtgcatcaccatggagggctggacagacgtcctgtactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacactaatcatcatagggtcattttttgtactt
aacttggttctcggtgttcttagcggagagttctccaaagagagggagaaggccaaggct
cggggagatttccagaaacttcgagagaagcagcagctggaagaggatctgaagggctac
ctggactggatcacccaggcagaggacattgaccctgagaatgaggatgaaggcatggat
gaggagaagccccgaaacatgagtatgcccacaagcgagaccgagtctgtcaacaccgaa
aacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccaccggatt
tccaaatcaaagttcagccgctactggcgccgctggaatcggttctgcagaagaaagtgt
cgtgccgcagtcaagtctaatgtcttctactggcttgtgatcttcctggtgttcctcaac
actctcaccattgcctcggaacactacaaccagccccactggctcacggaggtgcaagac
acggccaacaaggcgctgctggcccttttcactgcagagatgctgctgaagatgtacagc
ctgggcctgcaggcctacttcgtgtccctcttcaaccgcttcgactgtttcatcgtgtgt
ggtggcatcctggagaccatcctggtggagaccaagatcatgtctcccttgggcatctct
gtgttgagatgtgtccggctactgcggatatttaaaatcacaaggtactggaactcctta
agcaacctggtggcatccttgctgaattctgtgcgctccattgcctccctactgctgctc
ctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggaggaaagttc
aactttgatgaaatgcagacccggaggagcacatttgataactttccccagtccctcctc
accgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctggct
gatgctgagagcctcacatctgcccaaaaggaggaagaagaagagaaggagagaaagaag
ctggccaggactgccagcccagagaagaaacaagaggtggtggagaagccagcagtagag
gagaccaaggaggagaaaattgaactgaaatccattacagctgatggagagtccccaccc
accaccaagatcaacatggatgacctccagcccaatgaaaatgaggataagtgcccctac
cccaacccagaaaatacaggagaagaggatgaggaggagcctgagatgcctgtgggcccc
cgcccacgaccactctctgagctgcaccttaaggaaaaggcagtgcccatgccagaagcc
agtgcgtttttcatcttcagccccaacaacagatttcgcctccagtgtcaccgcattgtc
aatgacacgatcttcaccaacctgatcctcttcttcattctgcttagcagcatttccctg
gcagctgaggaccccgtccagcacacctccttcaggaaccatattctgttttattttgac
attgttttcactaccattttcaccattgaaattgctctgaagatcctaggcaatgcagac
tatgtcttcactagtatctttacattagaaattatccttaagatgactgcttatggggct
ttcctacacaagggctctttttgccgaaactacttcaacatcttggacctgctggtggtc
agcgtgtccctcatttcctttggcatccagtcaagtgcaatcaacgtggtgaagatctta
cgagtcctgcgagtcctcagacccctaagggccatcaacagggccaaggggctgaagcac
gtggttcagtgcgtgttcgtcgccatccggaccatcgggaacatcgtcattgtcaccacg
ctactccagttcatgttcgcctgcatcggggtccagcttttcaagggaaagctctacacc
tgctcagatagttccaaacagactgaggcggaatgcaagggtaactacatcacatacaag
gacggggaggtcgaccaccccatcatccaaccccgcagctgggagaacagcaagtttgac
tttgacaatgttctggcagccatgatggccctctttaccgtctctacctttgaggggtgg
ccagagctgctgtaccgctccatcgactcccacacagaagacaagggccccatctacaac
taccgtgtggagatctccatctttttcatcatctacatcatcatcattgccttcttcatg
atgaacatcttcgtgggtttcgtcatcgtcaccttccaagagcagggggagcaggaatac
aagaactgtgagctggacaagaaccagcgacagtgcgtggaatatgccctcaaggcccgg
cccctacggaggtacatccccaagaaccagcaccagtacaaagtgtggtacgtggtcaac
tccacctactttgaatacctgatgttcgtcctcatcctgctcaacaccatctgcttggcc
atgcagcactatggccagagctgcctcttcaaaattgccatgaacatcctcaacatgctc
ttcactggcctcttcaccgtggagatgattctgaagctcattgccttcaaacccaagggt
tactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagcataattgac
gtcattctcagtgaaactaatcactatttctgtgatgcatggaatacatttgacgccttg
attgttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacc
caatgctctccctttatgaacgcagaggagaactcccgcatctccatcaccttcttccgc
ctcttccgggtcatgcgcctggtcaagctgctgagccgcggagagggcatccggaccctg
ctgtggaccttcatcaaatccttccaggccctgccctatgtggcccttctgatagtgatg
ctgttcttcatctatgcggtgattgggatgcaggtgtttgggaaaattgccctgaatgac
accacagagatcaaccggaacaacaacttccagaccttcccccaagctgtgctgcttctc
ttcaggtgtgccaccggggaggcatggcaggacatcatgctggcctgcatgccagggaag
aagtgtgcccccgaatcggagcccagcaacagcacagaaggcgaaacaccctgtggcagc
agcttcgcggtcttctacttcatcagcttctacatgctttgtgccttcctgatcatcaac
ctctttgtagctgtcatcatggacaactttgactacctgacaagggactggtcaattctt
ggtccccatcatctggatgaatttaaaagaatctgggcagagtatgatcctgaagccaag
ggtcgtatcaagcacctagatgtggtgaccctgcttcgacggatccagcccccactgggt
tttgggaagctgtgccctcaccgcgtggcttgcaaacgcctggtctccatgaacatgcct
ctgaacagtgatgggacagtcatgttcaatgccaccctgtttgccctggtccggacagcc
ctgcgaatcaaaacagaagggaacctagaacaagccaatgaggagctgcgggccataatc
aagaagatatggaagcggaccagcatgaagctgttggaccaagtggtgcccccagcaggt
gatgacgaggtcacagttggcaagttttatgctactttcctgatccaagagtatttccgg
aaattcaagaagcgcaaagagcagggcctagtgggcaagccctcccagaggaacgccctg
tccctacaggccggcttgcgcacgctgcatgacatcgggcctgagatccgacgggccatc
tctggggatctgacggctgaggaggagctggacaaggccatgaaggaggctgtgtctgct
gcctccgaagacgacatcttcaggagggccggtggcctgttcggcaaccacgtcacctac
taccaaagcgacggccggagcgccttcccccagaccttcaccacccagcgcccactgcac
atcaacaaggcggctaacagccaaggcgacaccgagtcgccatcccacgagaaactggtg
gactccactttcacccccagcagctactcgtccactggctccaacgccaacatcaacaat
gccaacaacactgccctgggccgcttcccccgccccgctggttaccccagcgcggtcagc
accgtggagggccatgggccccccttgtctcctgccgtccgggtacaggaggcagcatgg
aagctcagctccaagaggtgccactcccgggagagccagatagccatggtgtgtcaggag
gaggtctctcaggacgagacctatgacgtgaagatgagcgaagacaccgagtactgcagc
gagcccagcctgatctccacagagatgctctcctaccaggatgatgaaaatcggcaatta
acaccacctgaggaggacaagagagacgtccggcaatctccaaagaggggtttcctccgc
tctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacagaagaat
caagggggagacatctctcagaagacagtcctgcccttgcatctggttcaccatcaggca
ttggcagtggcgggcctgagccccctcctccagagaagccattcccccagcacgttcccc
aggccatgtgccacccccccagccacgccgggcagccgaggctggcccccacagccgatc
cccaccctgcggctggagggggccgagtccagcgagaaactcaacagcagcttcccgtcc
atccactgcagctcttggtctggggagcccacgccctgcggtgcgggcagcagcgccatc
cggagagcccggccggtgtccctcactgtgcccagccaggctggggcccggggcaggcag
ttccacggcagcgccagcagcctggtggaagcggtcttgatttcagaaggactggggcag
tttgctcaagatcccaagtttatcgaggtcacaacccaggagctggctgacgcctgtgac
atgaccatagaagagatggagaacgccgccgacaacatcctcagtgggggcgcccagcag
agccccaacggcaccctactaccttttgttaactgcagggacccagggcaggacagagcg
gggggccaagagggcgagacctgcgccgcggctctggcgtgtcggaaaagcgaggaggag
ctccaggacagcagagcccacgccggcggcctgtag
DBGET
integrated database retrieval system
