KEGG   Ursus maritimus (polar bear): 103678069
Entry
103678069         CDS       T03271                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04012  ErbB signaling pathway
umr04014  Ras signaling pathway
umr04024  cAMP signaling pathway
umr04062  Chemokine signaling pathway
umr04360  Axon guidance
umr04392  Hippo signaling pathway - multiple species
umr04510  Focal adhesion
umr04625  C-type lectin receptor signaling pathway
umr04650  Natural killer cell mediated cytotoxicity
umr04660  T cell receptor signaling pathway
umr04666  Fc gamma R-mediated phagocytosis
umr04810  Regulation of actin cytoskeleton
umr05132  Salmonella infection
umr05170  Human immunodeficiency virus 1 infection
umr05205  Proteoglycans in cancer
umr05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103678069 (PAK1)
   04012 ErbB signaling pathway
    103678069 (PAK1)
   04014 Ras signaling pathway
    103678069 (PAK1)
   04392 Hippo signaling pathway - multiple species
    103678069 (PAK1)
   04024 cAMP signaling pathway
    103678069 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103678069 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103678069 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103678069 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    103678069 (PAK1)
   04660 T cell receptor signaling pathway
    103678069 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    103678069 (PAK1)
   04062 Chemokine signaling pathway
    103678069 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    103678069 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103678069 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    103678069 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103678069 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103678069 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103678069 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103678069 (PAK1)
   03036 Chromosome and associated proteins [BR:umr03036]
    103678069 (PAK1)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103678069 (PAK1)
Protein kinases [BR:umr01001]
 Serine/threonine kinases: STE group
  STE20 family
   103678069 (PAK1)
Membrane trafficking [BR:umr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    103678069 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    103678069 (PAK1)
Chromosome and associated proteins [BR:umr03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     103678069 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT YrbL-PhoP_reg
Other DBs
NCBI-GeneID: 103678069
NCBI-ProteinID: XP_040486829
UniProt: A0A384DEZ9
LinkDB
Position
Unknown
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDAATSPISPTENNTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAFFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacccccagcccctccgatgagaaacacc
agcactatgattggagctggcagcaaagatgctggaaccctaaaccacggttccaaacct
ctgcctccaaacccagaggagaagaaaaagaaggaccgattttaccgatccatcttacct
ggagataaaacaaataaaaagaaggagaaagaacggccagagatctctcttccttcagat
tttgagcacacgattcatgttggttttgatgctgtcacaggggagtttacagggatgcca
gagcagtgggctcgcctgcttcagacatcaaatatcactaagtcagagcagaagaagaac
ccacaggctgttctggatgtattggaattttataactcaaagaagacctccaacagccag
aagtacatgagctttacagataaatcagctgaggattataattcttctaacactttgaat
gtgaagacggtgtctgagacccctgctgtgccacccgtttcagaagacgaagatgatgat
gatgatgctaccccccctccagtgattgctccacgcccagagcacacaaaatctgtatac
acacggtctgtgatagaacctcttcctgttactccaactcgggatgcggctacatctcct
atttcacctacggagaataataccactccaccagatgctctgacccggaatactgagaag
cagaagaagaagcctaagatgtctgatgaggagatcttagagaaattacggagcatagtg
agtgtgggcgatcctaagaagaaatatacacggtttgagaagattggacaaggtgcttca
ggcactgtgtacactgcaatggatgtggccacaggacaggaggtggccattaagcagatg
aacctgcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttacctcgtgggagatgagctgtgg
gttgtcatggaatacttggctggaggttctttgacagatgtggtgacagaaacttgcatg
gatgaaggccagattgcagctgtctgccgtgagtgcctgcaggctttggagtttctgcat
tcgaaccaggtcattcacagagacatcaagagcgacaacatcctgttgggaatggatggc
tctgtcaagctaaccgattttggattctgtgcccagatcaccccagagcagagcaaacgg
agcaccatggtgggaactccatactggatggcgccagaggttgtgacacggaaggcctat
ggacccaaggttgacatctggtccctgggtatcatggccattgaaatgattgaaggagag
cccccatacctcaatgaaaatcctctgagagctttgtacctcattgccaccaatgggacc
ccagagcttcagaacccagagaagctgtcagctttcttccgggactttctgaatcgctgt
cttgagatggatgtggagaagagaggttcagctaaagagctgctgcagcatcagttcctg
aagattgccaagcccctctccagcctcactccactgattgctgcagcaaaggaggcaacc
aagaacaatcactaa

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