Ursus maritimus (polar bear): 103678344
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Entry
103678344 CDS
T03271
Symbol
ACACB
Name
(RefSeq) LOW QUALITY PROTEIN: acetyl-CoA carboxylase 2
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00061
Fatty acid biosynthesis
umr00620
Pyruvate metabolism
umr00640
Propanoate metabolism
umr01100
Metabolic pathways
umr04152
AMPK signaling pathway
umr04910
Insulin signaling pathway
umr04920
Adipocytokine signaling pathway
umr04922
Glucagon signaling pathway
umr04931
Insulin resistance
umr04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
103678344 (ACACB)
00640 Propanoate metabolism
103678344 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
103678344 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
103678344 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
103678344 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103678344 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
103678344 (ACACB)
04931 Insulin resistance
103678344 (ACACB)
Enzymes [BR:
umr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
103678344 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
103678344 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
103678344 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
103678344
NCBI-ProteinID:
XP_040475746
UniProt:
A0A8M1EY00
LinkDB
All DBs
Position
Unknown
AA seq
2456 aa
AA seq
DB search
MILLLFLSCLIFSCLTFSWLKIWGKMMDSKQVTKSKSEGSCIPSQEPFPASDCSGEPPQK
NGDRSPLPETPNQAEPASHKGPKDACGQRTSRPPPHQNAPGNPCSSDDAPAALQANGTGT
EGLRTPDTNGLSSPARPQGQRTRPLSKEDEKQEHLKRQLMTNFVLGSFDDNSSDEDPGAG
LFRESSRKSSRASLGTLSLEAALAVGESESPVPAMRPSMSGLHLVKRGRELKKVDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWAEEDLQWGKRI
TVPEDVYNQGCVKDIDEGLQMAEKIGFPLMIKASEGGGGKGIRKAESPEDFPILFRQVQS
EIPGSPVFLMKLAEHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAIPV
VFEIMEQCAVRLAKTVGYVSTGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFDTPANPPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETERFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNV
ADAMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYGGVKYILKVARQSLTMFVLIMND
CHIEIDAHRLSDGGLLLSYNGNSYTTYMKEEFDSYRITIGNKTCVFEKENDPTVLRAPSA
GKLLQYTVEDGGHVEAGSSYADMEVMKMIMTLSVQESGRVKYMKRPGAMLEAGCVVARLE
LDDPSKVHPAKPFTGELPSQQTLPIVGEKLHQVFHNVLENLTNVMSGYCLPEPIFSTKLK
EWVQKLMMTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRRAEREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEH
HFQQAHYDKCVINLRERLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVE
FQFMLPSSHPNRMAVPISVTNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFIRNF
DEVISCFANVPREAPLFGKACTSLYCEEDSKNPREEPIHILNVALQYADHLEDEELVPIF
RKFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLVTKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPELFRQALFKLWGTPDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRDVIVISNDITFRIGSF
GMGEDLLYLRASEMARAEGIPKIYLAANSGACIGLAEEIKHIFQVAWVDPGDPHKGLKYL
YLTPQDYTTISSLNSVHCRHIEEDGESRYVITDIIGKDSGVGIENLRGSGMIAGESSLAY
DEIVTISLVTCRAVGIGAYLVRLGQRVIQVENSHIILTGVSALNKVLGREVYTSNNQLGG
VQIMHYNGISHITVPDDFEGVCTILEWLSYMPKDNHSPVPIITPTDPIDREIGFFPTRAP
YDPRWLLAGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVVPADPANLDSEAKIIQQAGQVWLPDSAYKTAQAIKDFNRERLPLMIFANWRGFSG
GMKDMYDQMLKFGAYIVDSLRQYKQPVLIYIPPSAELRGGSWVVVDSSINPLCIEMYADK
ESRANILEPEGTVEIKYRKKDLIKTMRRIDPAYKKLVEQLGMSGLSDKDRKDLEGQLKAR
EDLLLPIYHQVAVQFADLHDSPTCLLEKGAISDILEWKTARSFXYWRLRRLLLEDQVKQE
ILRASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQGEDSLRSTVREN
IRCLKRDSVLKAIRGLVQDNPEVAVDCIVYMSQHISPAERAQVIHLLSTMDSAAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgatattgcttctttttctatcttgtttgattttctcctgcttgaccttttcctggtta
aaaatctgggggaaaatgatggactctaagcaagtcaccaagagtaaatcagaagggagc
tgtatcccaagccaggagccctttccagcctcagactgctcaggggagccaccacaaaaa
aatggtgaccgcagccctctgccagagactcctaaccaggctgagccagcctcccacaaa
ggtcccaaagatgcctgtgggcaaagaacttccaggccacccccacaccagaatgcccca
ggaaacccctgttcctctgatgacgcccccgcagcgctccaagccaatgggacggggacc
gaaggcctgaggaccccggataccaatggcctgtcatctccagccaggcctcagggccag
cgaaccagaccgctctccaaagaagacgagaagcaggagcacctcaagaggcagctgatg
accaacttcgtcttgggctcctttgatgacaactcgtccgatgaggaccctggtgcgggc
ttgttccgagagtcctcccggaagagcagccgggccagcctggggaccctgtccctggag
gccgctctggctgtaggcgagtctgagagccccgtccccgctatgagacctagcatgtcg
ggactccacctggtgaagaggggccgagaactgaagaaggtggacctgcacagagacttt
accgtggcctccccagctgagtttgtcacgcgctttgggggggaccgggtcattgagaag
gtgctcatcgccaacaatggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgg
gcctatgagatgttccgcaacgagcgggccatccggtttgtagtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtatgtccctgtcccagga
gggcccaacaacaacaattatgccaacgtggagctggttgtggacattgccaagaggatc
cccgtgcaggcggtgtgggctggctggggccatgcttctgaaaaccccaaactgccggag
ctcctgtgcaagcatgagattgctttcttaggccctcccagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtagcccagacgctgcagatcccaacactgccctgg
agtggaagcggtctgacggtggaatgggcagaagaggatctgcagtgggggaagaggatc
actgtcccggaagatgtttacaaccagggttgtgtgaaagatatagatgagggcttacag
atggcagaaaaaattggttttcccttgatgatcaaagcatctgaaggcggcggagggaaa
ggaatccggaaggcagagagtcccgaggacttcccaatccttttcagacaagtgcagagt
gagatccctggctcccccgtcttcctcatgaagctggccgagcatgcccgacacctggag
gtccagatcctcgccgaccagtatgggaacgccgtgtccctgttcgggcgtgactgctcc
atccagcggcggcatcagaagatcattgaggaggcgccggccaccatcgccataccggtt
gtgttcgagatcatggagcagtgtgccgtccgcctggccaagacggtgggctacgtgagc
acggggacggtggagtatctctacagccaggatggcagcttccacttcttggagctgaat
ccccgtctgcaggtggagcacccctgcacagagatgatcgccgacgtcaacctgcctgcc
gcccagttacagattgccatgggggtgcccctgcaccgcctgaaggatatccggcttctg
tatggagagtcgccgtggggggtgacacccatttcgttcgacactcctgccaaccctcca
ctcgcccgaggccatgtcattgcggctagaatcaccagtgagaaccccgatgaggggttt
aagccaagctctggaacggttcaggagctgaatttccggagcaacaagaacgtgtggggt
tacttcagcgtagcggctgccggcggcttacacgagtttgctgattcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gaactgtccatccggggcgacttcagaaccaccgtggagtatctcattaacctgctggag
actgagcgcttccagaacaatgacatcgacacaggctggttggattacctcatcgccgag
aaagtgcaggcggagaagccggatatcatgctcggggtggtgtgcggagccttgaacgtg
gccgatgcgatgttcagaacttgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgcagcttctctgctgaacatcgtggatgtggaactaatttatggaggtgtt
aagtacattctcaaggtggcccggcaatctctgaccatgttcgtcctcatcatgaacgac
tgtcacatcgagatcgacgcccaccggctaagcgacggggggttgctgctgtcctataat
ggtaacagctataccacctacatgaaagaagagtttgacagttaccgtattaccatcggc
aacaagacgtgtgtgtttgagaaagagaacgatcccacggtcctgagagccccttcggct
gggaagctgctgcagtacacggtggaggacgggggccacgttgaggctgggagcagctac
gctgacatggaggtgatgaagatgatcatgaccttgagcgtgcaggaaagtggccgggtg
aagtacatgaagcgcccgggggccatgctggaggcaggctgtgtggtggccaggctggag
ctcgatgacccttccaaagtgcacccggccaagccattcacaggagagctcccttcccag
caaactctgcccatcgtgggagagaaactgcaccaggttttccacaatgtcctggaaaac
ctgaccaacgtcatgagtggctactgtctgccggagcctatttttagcacaaagctgaag
gagtgggtgcaaaagctcatgatgaccctccggcacccatcactgccgctgctggagctg
caggaaatcatgaccagtgtgtccggccgtatccccgcccccgtggagaagtcggtccgc
agggtgatggctcagtacgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccaccatcctggactgccacgcggccaccctgcagcggagggccgaacgggag
gtcttcttcatgaacacccagagcattgtgcagctggtccagaggtaccgcagcgggacc
cgcggctacatgaaggcggtggtgttggacctcctgcggagatacttgcgggtggagcat
catttccagcaagctcactacgacaagtgcgtgataaacctcagggagcggctgaagcca
gacatgtcccaggtgctggactgcatcttctcccacgcgcaggtggccaagaagaaccag
ctggtgatcatgttgattgatgagctctgtggcccagacccttccctgtcggaagagctg
acctccatcctcaatgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc
agagccagacaggtcctgattgcctcccacctcccgtcctacgagctgaggcacaaccag
gtggagtccattttcctgtctgccatcgacatgtacggccaccagttctgcccagaaaac
ctcaagaaattaatactctcagaaacaaccatatttgatgtcctgcccactttcttctac
cacgctaacaaagtcgtctgcatggcatccttggaggtttacgtgcggaggggctatatc
gcctatgagttaaacagcttgcagcaccggcagctcccggacggcacctgcgtggtggaa
ttccagttcatgctgccctcctcccacccaaacaggatggccgtgcccatcagcgtcacc
aaccccgacctgctgaggcacagcaccgagctcttcatggacagcggcttctccccactg
tgccagcggatgggggccatggtcgccttcaggagattcgaggacttcataaggaacttc
gacgaggtcatctcctgctttgccaacgtgccccgggaagcccccctcttcggcaaggcc
tgcacttccctgtactgtgaggaagacagcaagaaccccagagaagagccgatccacatc
ctgaatgtggccctccagtacgcggaccacctggaagatgaggagctggtgccgattttc
cggaagttcgtacagtccaagaaaaacatccttgtggattacggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttcccaagtttttcacgttcagagcaagagacgag
ttcgcggaagatcgcatttaccgtcatctggagcccgccctggccttccagctggagctc
agccgcatgcgcagctttgacctgaccgccgtgccctgcgccaaccacaagatgcacctg
tacctgggcgccgccaaagtgaaggagggcgcggaagtgacggaccaccgcttcttcatc
cgcgccatcatccgccactcagacctcgttacaaaggaagcctcctttgagtacctgcag
aacgagggcgagcgtctgctcctggaggccatggacgagctggaggtggcattcaacaac
acgagcgtacgcaccgactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatg
gacccctccaagatcgaggagtccgtgcgttccatggttatgcgctatggcagccggctg
tggaaactgcgcgtgctgcaggctgaggtcaagatcaacatccgccagaccaccactggc
agcgctgttcccatccgcctgttcatcaccaatgagtcgggctactacctggacatcagc
ctctacaaagaagtcaccgaccccagatccggaaacatcatgtttcactcctttggcaac
aagcagggaccccagcacgggatgctgatcaacaccccgtatgtcaccaaggatctgctt
caggccaagcggttccaggcccagtccctgggcaccacctatgtctacgacttcccggag
ctgttcagacaggctctctttaaactgtggggcaccccggacaagtaccccaaagacatc
ctgacatataccgaactcgtgctggaccctcagggccagctcgtggagatgaaccgcctt
cctggaggaaatgaggtgggcatggtggccttcaaaatgaggttcaagaccccagaatat
ccggaaggacgggacgtgatcgtaatcagcaatgacatcacgttccgcatcggatccttc
ggcatgggagaagacctcttgtacctgcgggcctccgagatggcccgggcagagggtatc
cccaaaatctacctcgcagccaacagcggggcctgtatcggccttgcagaggagatcaag
cacatattccaggtggcttgggtggacccaggagacccccacaaaggacttaagtacttg
tacctgacgccccaagactacaccacaatcagctccctgaactctgtccattgtaggcac
atcgaagaagacggggaatccaggtatgtcatcacggatatcatcgggaaggacagtggt
gtgggcatagagaatctcaggggctccggcatgatcgcgggggagtcctccctggcttac
gacgagattgtcaccatcagcttggtgacttgccgagccgtggggatcggggcctacttg
gtgaggctgggtcagcgagtgatccaggtggagaactctcacatcatcctgacgggagtc
agcgctctcaacaaggtgctgggcagagaggtctacacgtccaacaaccagctgggcggc
gtgcagatcatgcattacaatggcatctcccacatcactgtgccagatgacttcgagggc
gtttgtaccatcctggagtggctgtcctatatgccaaaggataatcacagcccagtcccc
atcatcacacccacggaccccattgacagagaaattggattcttcccgacccgggctccc
tatgacccccggtggctgctggcaggaaggcctcacccgactctgaagggatcctggcag
agtggattctttgaccatggcagtttcaaggaaatcatggcgccctgggcccagaccgtg
gtgacaggacgagcaaggctaggggggatccctgttggcgtgatcgccgtggagacacgg
accgtggaggtggtggtgcctgcggaccctgccaacctggactcagaggccaagataatc
cagcaggcaggccaggtgtggctcccagactccgcctacaagacggcccaggccatcaag
gatttcaaccgagagaggttgcccctgatgatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccagatgctaaagttcggagcctacatcgtggacagtctc
aggcagtacaagcagcccgtcctgatctacatcccaccctccgcggagctccgggggggc
tcctgggtggtcgtggactcctccatcaaccccctgtgcatagaaatgtacgcggacaag
gagagcagggcgaatattctggagccggagggcacggtggagattaagtaccgaaagaaa
gatctgataaagaccatgagaaggattgacccagcttacaagaagctcgtggaacagcta
ggaatgtcggggctctccgacaaggaccgcaaggacctggagggccagctgaaggcccgg
gaggacctgctgctgcccatctaccaccaggtggcggtgcagttcgccgacctccacgac
agccccacctgcctgctggagaagggcgccatctccgacatcctggagtggaagaccgcg
cgctccttcnngtactggcgcctgcgccgcctcctgctggaggaccaggtcaagcaggag
atcctgcgggccagcggcgagctgagccacgtgcacatccagtccatgctgcgccgctgg
ttcgtggagacggagggcgccgtcaaggcctacctgtgggacaacaaccagatggtggtg
cagtggctggaacagcactggcagggggaggacagcctgcgctccactgtccgcgagaac
atcaggtgcttgaagcgagactccgtcctcaaggccatcagaggcctggttcaggacaac
cctgaagtggccgtggactgcatcgtgtacatgagccagcacatcagcccggccgagcgg
gcccaagtcattcacctcctgtccaccatggacagcgcagcctccacctga
DBGET
integrated database retrieval system
