Ursus maritimus (polar bear): 103679407 Help Entry 103679407         CDS       T03271                                  Symbol TPH1 Name (RefSeq) tryptophan 5-hydroxylase 1   KO K00502   tryptophan 5-monooxygenase [EC:1.14.16.4] Organism umr  Ursus maritimus (polar bear) Pathway umr00380   Tryptophan metabolism umr00790   Folate biosynthesis umr01100   Metabolic pathways umr04726   Serotonergic synapse Module umr_M00037   Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     103679407 (TPH1)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     103679407 (TPH1)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     103679407 (TPH1) Enzymes [BR:umr01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.4  tryptophan 5-monooxygenase      103679407 (TPH1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Biopterin_H ACT TH_ACT ACT_4 zf-C2HE GmrSD_N Motif Other DBs NCBI-GeneID:  103679407 NCBI-ProteinID:  XP_008707155 UniProt:  A0A384DK33 A0A452VGJ8 LinkDB All DBs Position Unknown AA seq 444 aa AA seqDB search MIEDNKENKDHSLERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTVKEDGMETVPWFPKKISDLDHCAN RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHSLSGHAKVKPFDPKVTC KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA MNELQHDLDVVSDALAKVSREPSI NT seq 1335 nt NT seq  +upstreamnt  +downstreamnt atgattgaagacaataaggaaaataaagaccattccttggaaagaggaagagcaacgctc attttttccttgaagaatgaagttggtggacttataaaagcactaaaaatcttccaggag aagcatgtgaacctgttacatatcgagtcccgaaaatcaaagagaagaaactcagaattt gagatttttgttgactgtgatatcaacagagaacaactgaatgatatttttcatctgttg aagtcccatactaatgttctctctgtgaatccaccagataattttactgtgaaggaagat ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccattgtgccaac agagttctgatgtatggatctgaactggatgcagatcatcctggcttcaaagacaatgtc taccgtaaaagacggaagtattttgcagacttggctatgaactataaacatggagacccc attcccaaggttgaattcactgaagaggagattaagacctggggaaccgtgtttcaagag ctcaacaaactttacccaacccatgcctgcagagagtacctcaaaaacttacctttgctt tctaagtattgtggatatcgggaagataatatcccacaattggaagatgtctcaaacttt ttaaaagagcgcacgggtttttccatccgtcccgtggctggttacttatcaccaagagat ttcttatcaggtttagccttccgggttttccactgcacacagtacgtgagacacagttcc gaccctctctataccccagagccagatacttgccatgaactcttaggtcatgtccccctt ttggcggaacctagttttgctcaattctcccaagaaattggcctggcttcccttggagct tcagaggaggctgttcaaaaactggcaacgtgctactttttcactgtggagtttggtctc tgtaaacaagatgggcagttgcgagtctttggggctggattactttcttctatcagtgaa cttaagcattcactttctggacatgccaaagtaaagccctttgatcccaaggttacctgc aaacaggagtgtctcatcacaacttttcaggatgtctactttgtatctgaaagctttgaa gatgcaaaggaaaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag tataatccatacacacggagtattcagatcttgaaagacaccaagagcataaccagcgcc atgaacgagctgcagcatgatctcgatgttgtcagtgatgcccttgcaaaggtcagcaga gagccaagcatctga

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