KEGG   Ursus maritimus (polar bear): 103680014
Entry
103680014         CDS       T03271                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1
  KO
K14381  sequestosome 1
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04137  Mitophagy - animal
umr04140  Autophagy - animal
umr04217  Necroptosis
umr04218  Cellular senescence
umr04380  Osteoclast differentiation
umr05014  Amyotrophic lateral sclerosis
umr05022  Pathways of neurodegeneration - multiple diseases
umr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103680014 (SQSTM1)
   04137 Mitophagy - animal
    103680014 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    103680014 (SQSTM1)
   04218 Cellular senescence
    103680014 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103680014 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103680014 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    103680014 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103680014 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103680014 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:umr03029]
    103680014 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103680014 (SQSTM1)
Membrane trafficking [BR:umr04131]
 Autophagy
  Mitophagy
   Cargo receptors
    103680014 (SQSTM1)
  Pexophagy
    103680014 (SQSTM1)
  Aggrephagy
    103680014 (SQSTM1)
  Xenophagy
    103680014 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    103680014 (SQSTM1)
Mitochondrial biogenesis [BR:umr03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    103680014 (SQSTM1)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   103680014 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 ZZ PB1
Other DBs
NCBI-GeneID: 103680014
NCBI-ProteinID: XP_040478565
UniProt: A0A8M1F8N9
LinkDB
Position
Unknown
AA seq 442 aa
MASLTVKAYLLGKEDAAREIRRFSFCFSPEAEAEAEAEAEAAAGPGPCERLLSRVAALFP
VLRPGGFQAHYRDEDGDLVAFSSDEELSMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQE
APRGLVHPNVICDGCNGPVVGTRYKCSVCPDYDLCAACEGKGLHREHSKLVFPAAFGPFS
EGFSHSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPRAGDARPGPAAESAAGPSEDPSVNF
LKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPGSSSTEEKCGSQPSSCSSDPSKP
DGDPEGSGRSLAGRCRRLVCSQVVLFQEQMESDNCSGGDEDWTHLSSKEVDPSTGELQSL
QMPESEGPGSLDSSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRL
LQTKNYDIGAALDTIQYSKHPL
NT seq 1329 nt   +upstreamnt  +downstreamnt
atggcgtcgctcaccgtgaaggcctatcttctgggcaaggaggacgcggcccgcgagatc
cgccgcttcagtttctgcttcagccccgaggccgaggcggaggccgaggctgaggcggag
gccgcggccgggcccgggccctgcgagcggctgctgagccgggtggccgccctgttcccg
gtgctgcggcccggcggcttccaggcgcactaccgcgatgaggacggagacttggtggcc
ttttccagtgacgaggaactgagcatggcgatgtcctatgtgaaggatgatatctttcgg
atttacatcaaagagaagaaggagtgtcggcgggaccaccgccccccgtgtgcccaggag
gcaccccgcggcctggtgcaccccaacgtgatctgtgacggttgcaatgggccagtggtg
gggacccgctacaagtgcagcgtgtgcccggactacgacctgtgcgccgcctgcgagggg
aagggccttcaccgggagcacagcaagctcgtcttccccgccgcctttgggcccttctcc
gagggcttctctcacagccgctggctccggaagctgaagcacgggcacttcgggtggccc
ggctgggagatgggcccaccggggaactggagcccgcgtcctccccgagcaggggatgcc
cgccccggccctgcagcagaatcagctgctggcccgtcggaggatcccagtgtgaatttc
ctcaagaacgtaggggagagtgtggcggctgccctgagccctctgggcatcgaagtggat
atcgacgtggaacacggagggaagagaagccgcctcacccccgtctctcccggcagctcc
agcaccgaggagaagtgcggctctcagcccagcagctgctcttcggaccccagcaaaccg
gatggggaccctgagggcagcggacgcagtctcgccggcagatgtcggaggctggtgtgc
tcacaggtggttctgttccaggaacagatggagtctgataactgctcgggaggagacgaa
gactggactcatctgtcttcaaaagaagtggacccatctacaggggagctccagtctctg
cagatgcccgaatccgaggggccgggctctctcgactcttctcaggaagggcccacgggc
ctgaaggaagctgcgttgtacccacatctgccaccagaagctgacccccggctcatcgag
tcgctctcccagatgctgtccatgggcttctcggatgagggcggctggctcaccaggctc
ctgcagaccaagaactacgacatcggggccgcactggacaccatccagtattccaagcac
ccgttgtga

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