KEGG   Ursus maritimus (polar bear): 103681471
Entry
103681471         CDS       T03271                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00670  One carbon pool by folate
umr00790  Folate biosynthesis
umr01100  Metabolic pathways
umr01240  Biosynthesis of cofactors
umr01523  Antifolate resistance
umr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    103681471 (DHFR)
   00670 One carbon pool by folate
    103681471 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    103681471 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103681471 (DHFR)
Enzymes [BR:umr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     103681471 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 103681471
NCBI-ProteinID: XP_008709257
UniProt: A0A384DQC1
LinkDB
Position
Unknown
AA seq 187 aa
MVRTLNCIAAVSQNMGIGKNGDLPWPPLRNEFKFFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRDLKEPPQGAHFLGKSLDDALKLIEQPELANKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDLDKYKLLPEYPGVPSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtacgctaaactgcatagccgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggcccccgctcaggaatgaattcaagtttttccaaagaatgaccaca
acctcctcagtagaagggaaacagaatttggtgattatgggtaggaagacatggttctct
attcctgagaagaatcgacctttaaaggacagaattaatttagttctcagcagagacctc
aaggaacctccacaaggagctcattttcttggcaaaagtctggatgatgccttaaaactt
attgagcaaccagaattagcaaataaagtggacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaaaccaggccatcttagactatttgtgacaaggattatg
caggaatttgaaagtgacacattttttccagaaattgatttggacaaatacaaacttctg
ccagaatacccaggtgttccttctgatgtccaggaggagaaaggcattaagtacaaattt
gaagtatatgagaagaacgattaa

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