KEGG   Vibrio cholerae O1 MJ-1236: VCD_001233
Entry
VCD_001233        CDS       T00903                                 
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
vcj  Vibrio cholerae O1 MJ-1236
Pathway
vcj00270  Cysteine and methionine metabolism
vcj00450  Selenocompound metabolism
vcj00670  One carbon pool by folate
vcj01100  Metabolic pathways
vcj01110  Biosynthesis of secondary metabolites
vcj01230  Biosynthesis of amino acids
vcj04981  Folate transport and metabolism
Module
vcj_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:vcj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    VCD_001233
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    VCD_001233
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    VCD_001233
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    VCD_001233
   04980 Cobalamin transport and metabolism
    VCD_001233
Enzymes [BR:vcj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     VCD_001233
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ACQ59406
LinkDB
Position
1:complement(227349..231029)
AA seq 1226 aa
MGKEVRQQLEQQLKQRILLIDGGMGTMIQSYKLQEEDYRGARFVDWHCDLKGNNDLLVLT
QPQIIKEIHSAYLEAGADILETNTFNSTTIAMADYDMQSLSAEINFAAAKLAREVADEWT
AKDPSRPRYVAGVLGPTNRTCSISPDVNDPGFRNVTFDGLVEAYSESTRALIKGGSDLIL
IETIFDTLNAKACAFAVDSVFEELGISLPVMISGTITDASGRTLSGQTTEAFYNALRHVR
PISFGLNCALGPDELRQYVEELSRISECYVSAHPNAGLPNAFGEYDLSAEEMAEHIAEWA
QAGFLNLVGGCCGTTPEHIAAIAKAVEGVKPRALPDLKVECRLSGLEPLNIGPETLFVNV
GERTNVTGSARFKRLIKEEQYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNL
CASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFIAQAKLVRRYGAA
VIVMAFDEVGQADTRERKLEICRRAYHILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYA
LDFINAVADIKRELPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKHGMDMGIVNA
GQLEIYDNVPLKLREAVEDVILNRRSDGTERLLEIAEAYRENSVGKEEDASALEWRAWPV
AKRLEHALVKGITEFIVQDTEEARQQASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVV
KSARVMKQAVAYLEPFINAQKSGSTSNGKILLATVKGDVHDIGKNIVGVVLQCNNFEIID
LGVMVPCEQILKVAREQNVDIIGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSK
AHTAVKIEQNYHAPVVYVNNASRAVGVCTSLLSDEQRPGFIERLDLDYERTRDQHARKTP
KSRPVTLEQARANKAALDWANYTPPAPAKPGVHVFENIALATLRPYIDWTPFFMTWSLMG
KYPAILEHEEVGEEAKRLFHDANALLDKVEREGLLKASGMCALFPAASVGDDIEVYSDES
RTQVAHVLYNLRQQTEKPKGANYCLSDYVAPKESGKRDWIGAFAVTGGIGERALADAYKA
QGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYASDENLSNDDLIRERYQGIRPAPG
YPACPEHTEKATLWQMLNVEETIGMSLTTSYAMWPGASVSGWYFSHPDSRYFAVAQIQPD
QLHSYAERKGWRLEEAEKWLAPNLDA
NT seq 3681 nt   +upstreamnt  +downstreamnt
gtgggaaaagaagtaagacaacaactcgaacagcaattgaaacaacgtatcctactgatt
gatggtggtatgggtaccatgattcagagttataagttacaagaggaagactatcgcggt
gcacgatttgtcgattggcactgtgatttgaaaggaaataacgacctcttagtgcttact
cagccgcaaattattaaagagattcactccgcttaccttgaagcgggggcggatattctt
gagaccaacacctttaactcaaccacgattgccatggcagactatgacatgcaatcgctc
agtgctgaaattaactttgccgcggctaagcttgcacgtgaagtcgcggatgagtggacg
gctaaagatccaagtcggccacgctatgtggctggtgtgcttgggccaaccaaccgtact
tgctctatttcgccagatgtgaacgatccaggatttcgtaacgtcacttttgatgggctt
gttgaagcctattccgaatcgacgcgcgctttgatcaaaggtggcagcgatctgatcctc
attgaaaccatcttcgatacacttaacgccaaagcctgtgcgtttgcggtcgatagcgta
tttgaagagctgggcatcagcttacctgtgatgatttccggcacgattaccgatgcctct
gggcgaactctgtcaggacagacaacggaagctttctacaacgccttgcgtcatgtacgg
ccgatttcgtttggcttgaactgtgcgttaggtcctgatgagctgcgccagtacgtggaa
gagctttcacgcatttcagaatgctatgtttccgcgcacccaaatgccggactgcccaat
gcgtttggtgaatacgatctctctgccgaggaaatggcagaacatattgcggaatgggca
caagctggctttttgaatttggtcggtggttgctgtggaactacacctgagcatatcgcc
gccattgccaaagccgtcgagggtgtaaaaccaagggctctgccagatctgaaagtagaa
tgtcgtctctcgggtttagagccgctcaatattggtcctgaaaccttgtttgttaacgtg
ggcgaacgtactaacgtcaccggttctgcgcgttttaagcgtttaattaaagaagagcaa
tacgacgaagcgctcgatgtggcgcgtgagcaagtcgaaaacggcgcgcagatcattgat
atcaacatggatgaaggcatgttggacgccgaggcgtgtatggtgcgctttttgaatcta
tgcgcctctgaaccagaaatatccaaagttccggtgatggtcgactcctctaaatgggaa
gtcattgaagcgggtctgaaatgcattcagggtaaaggcatcgtcaactctatctctcta
aaagaagggaaagagaagtttattgcccaagccaaattggtgcgccgctacggtgccgcg
gtgattgtgatggcatttgacgaagtgggccaagccgatacccgtgagcgcaaattagag
atctgtcgtcgggcttaccatattttggtcgatgaggtgggcttcccaccggaagatatt
atttttgacccgaacatctttgctgttgcgaccggaattgatgagcacaataactacgca
ctggatttcattaatgcagtggcggacattaagcgtgagctgccgcatgcgatgatttct
ggcggtgtttctaacgtttccttctctttccgcggcaacaactatgtgcgtgaagcgatc
catgctgttttcctttatcactgcttcaaacacggcatggacatggggattgtcaacgca
gggcagcttgaaatctacgataacgttccgctgaaactgcgtgaggcagtggaagatgtg
atcctcaatcgacgtagcgatggcacggaaagactgcttgagatcgccgaagcgtatcgc
gaaaacagtgttggtaaagaagaggatgcttctgcattagagtggcgcgcatggcctgtg
gctaagcgcctagagcacgctttagtcaaaggcatcaccgaatttatcgtccaagacact
gaagaagcacgtcagcaagccagtaaaccactggaagtgattgaagggccgctgatggat
ggtatgaacgtggtcggtgacttgttcggggaagggaaaatgttcctaccgcaagtcgta
aaatcagcgcgtgtcatgaaacaagccgttgcgtatcttgagcctttcattaatgcgcaa
aaaagtggtagcacttcaaatggtaagattttgctggcgaccgtaaaaggcgatgtgcat
gacattggtaagaacattgttggcgtcgtgctgcagtgtaataacttcgagatcatcgat
cttggtgtgatggtgccttgcgagcagatcctcaaagtcgcacgcgagcaaaatgtcgat
atcatcggtctctctgggcttatcacgccgtctttggatgagatggtacacgtggcgaaa
gagatggagcgacaagggtttgaactgccacttttgattggtggggcaacaacgtctaaa
gcgcatactgcggtgaagattgaacagaattatcatgcgcctgtagtgtacgtgaataac
gcgtcgcgcgcggtaggggtgtgcacatcattattgtctgatgaacagcgccccggattt
atcgaacgtttggatctcgattatgagcgcacgcgtgatcagcatgctcgtaaaacgccc
aaatcgcgcccagtcacgttagagcaggcacgtgctaataaagcggcgctggattgggca
aattacacgccgcccgctcctgcgaaaccgggtgtgcatgtgtttgaaaacattgcgtta
gccacactacgtccttatatcgattggacgcctttttttatgacttggtcgcttatgggc
aaataccctgccattttggagcatgaagaggtcggtgaagaggccaaacgtctgtttcat
gatgccaatgccttacttgataaagtagagcgagaaggactactgaaagccagtggtatg
tgtgcactgtttccagcagccagcgtgggcgatgacattgaggtgtacagtgatgaatcg
cgtacgcaagtcgcgcatgtgctgtacaacttgcgtcagcagactgagaaaccgaaaggg
gccaactactgtttgtcggactatgttgctccgaaagagagcggtaaacgtgattggatt
ggcgcgtttgcagtaactggtggcattggtgagcgagccttggccgatgcttataaagct
cagggtgatgattacaatgcgatcatgatccaagcggtagccgatcgtttggcggaagcc
tttgcggaatatctgcatgaaaaagtgcgtaaagagatttggggttatgcgagcgatgaa
aatctctccaatgatgacctgatccgtgagcgttatcagggcattcgacccgcgccgggg
tatcccgcgtgtcctgagcataccgagaaagcgactttgtggcagatgctaaatgtcgaa
gagaccataggtatgtcactgaccacaagctatgcgatgtggccgggcgcttcggtatcc
ggttggtatttctcgcatcccgattctcgctattttgcggtagcgcagatccaaccagat
caactgcacagctacgctgagcgtaaaggttggcgtttggaagaagctgaaaagtggcta
gcgcctaaccttgatgcttaa

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