| Entry |
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| Symbol |
metL
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| Name |
(GenBank) methionine-sensitive aspartokinase II/homoserine dehydrogenase
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| KO |
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| Organism |
vcm Vibrio cholerae O1 M66-2
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| Pathway |
| vcm00260 | Glycine, serine and threonine metabolism |
| vcm00270 | Cysteine and methionine metabolism |
| vcm01110 | Biosynthesis of secondary metabolites |
| vcm01120 | Microbial metabolism in diverse environments |
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| Module |
| vcm_M00016 | Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine |
| vcm_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
| vcm_M00018 | Threonine biosynthesis, aspartate => homoserine => threonine |
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| Brite |
KEGG Orthology (KO) [BR:vcm00001]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VCM66_2604 (metL)
00270 Cysteine and methionine metabolism
VCM66_2604 (metL)
00300 Lysine biosynthesis
VCM66_2604 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VCM66_2604 (metL)
Enzymes [BR:vcm01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VCM66_2604 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VCM66_2604 (metL)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
I:2788613..2791024
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| AA seq |
803 aa
MTHPRQLHKFGGSSLADPECYQRVAKILKSYSKSDDLVVVSAAGKTTNRLISFVEALSKD
GRVAHETLHALRQYQSELITKLLSNEAAEPLLSQLQQEISVLGELTAPLSNAQYAWVLGH
GELWSARLLAALLNQQDLPAVAQDARTFLRAEAGTQPEVDRARSYPLLKAVLAQHTQRRV
VITGFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSADPRIVSDACL
LPLLRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPESGSTRIERVLASGRGA
KIITSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQPDQYRLRLAYTAEI
APGAFAALQDAAFEAEIKLKEGYDLIAAVGAGVTKNPNHCYGFYQQLNALPVEFISASES
SLSLVAVLRQTPIHSLVNAIHKQLFQAQKHVAIALCGKGNIGSSWLKLFAEQKEKLEQRH
GMNFELVAVVDSQTYWFNEQGINPNQVATHFQDEALPNQEQSWLKKLGALEGYDEAVVID
VTASEELAEQYLDIAEHGLHLISANKVAGSAAGNYYYQVKDAFHKIGRHWLYNATVGAGL
PINHTVRDLRESGDDIMALSGIFSGTLSWLFQQYDGSLPFSELVDLAWQQGLTEPDPRCD
LDGSDVMRKLVILARESGLEIEPQNVKVESLVPAELRSVSLDDFLDNSKLLNEQLAERLA
RAQKQGKVLRYVARLEKNGKASVGVEALEQDHPLANLLPCDNIFAIESKWYRDNPLVIRG
PGAGREVTAGAIQSDLNLLASLL |
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| NT seq |
2412 nt +upstreamnt +downstreamnt
atgacccatccccgtcaattgcataaatttggtggtagtagccttgccgaccctgagtgt
tatcaacgtgtcgcgaaaattcttaaaagttattccaaaagtgatgatctggtggtggtt
tctgcggctggcaaaaccactaaccgtttgatcagttttgtcgaagcactcagtaaagat
ggtcgcgttgcccatgaaaccttacatgcgctgcgccaatatcagtctgaattgattact
aagctactcagcaacgaagcagccgaaccactacttagccaactgcaacaagagatcagc
gtgttaggcgagctcacagctcctcttagtaacgcacaatacgcttgggttttaggacat
ggtgagctctggtcggcacgcctgctcgccgcgttactgaaccagcaagatttaccagcg
gtcgcacaagatgcgcgaacatttttacgtgccgaagcaggcacacagccggaagtcgat
cgcgcgcgctcttacccactactgaaagccgtgttggcacaacatacccagcgccgcgtg
gtgatcaccggttttatggcgcaaaacgaacagggcgatactgtcctgctcggtcgtaac
ggttccgattattctgcgaccgtgattggcgcactggctgaagtctcacgcgtgaccatt
tggagtgatgtggctggcgtgtacagtgccgatccacgcattgtcagcgatgcctgtttg
ctgccactgctaagactcgatgaagccaatgagctggcacgcttagctgcgccagttctg
cacagccgtacactccaacctgtcgcgcagagcaccatggagcttcacttacgttgcagc
caccaaccggaatcgggctctacccgtattgaacgggtactggcttctggtcgcggcgcg
aaaatcattacttcgctcgatgatgtgctgctgattgagctgagctttgctcatcaccat
gatttccaacgtgtgcaagaagatgtgttacagcacttgcagcgcgtgcaactgcaaccg
ctgacttacgaagcacaacctgaccaataccgtttgcgtttagcctacacagcagaaatt
gcgcctggcgcgtttgcggcgctgcaagatgccgcgttcgaggcggaaatcaaactcaaa
gaaggctatgacctgattgctgcggtcggtgcgggcgtcactaaaaacccgaaccactgt
tatggcttctaccaacagctgaatgccttaccggtcgagtttatcagcgcgtcagaatca
agcctcagtttggttgccgtactgcgtcaaacgccgattcattcattggttaacgccatt
cacaaacagctcttccaagctcaaaaacacgtcgcgattgcgctgtgtggcaaaggcaat
attggctccagctggctcaagttgtttgccgaacaaaaagagaaattggaacaacgccac
ggcatgaattttgagttggttgcggtagtcgatagccaaacctactggtttaatgagcaa
ggcattaatccaaaccaagtggccacgcatttccaagatgaagcactgcccaaccaagag
caaagctggctgaaaaaactcggcgcattagaagggtacgatgaagccgtcgtgattgat
gtcaccgccagcgaagagttagctgagcagtatctcgatattgccgaacacggtttgcac
ctgatttccgccaacaaagtggcaggctctgctgcggggaattattactatcaagttaaa
gatgcctttcacaaaattggccgccactggctgtataacgccacggtaggcgcgggctta
ccaattaaccacacggtgcgtgacctacgtgaaagcggcgatgacatcatggcgttatcc
gggattttctccggcacactctcatggctgttccagcaatacgacggcagcttgccattc
agtgaactggtggatttagcatggcaacaaggcttaacagagcccgatccgcgctgcgat
ctcgacggttctgatgtcatgcgtaaattggtgatcttggcgcgtgaatctggccttgag
attgagccgcagaatgtcaaagtggaatcattggtacctgccgagctgcgctctgtatca
ctggatgattttctcgataacagcaaactgctcaacgagcagctcgccgaacgcctcgcc
cgtgcgcagaagcaaggcaaggtgctgcgctacgtcgcaaggctagagaaaaatggcaaa
gccagcgtgggtgtagaagcgcttgagcaagatcatccactggctaacttactgccgtgt
gacaacatctttgccatcgagagcaaatggtatcgcgataatccattggtgatccgaggt
cccggcgctggacgtgaagtcaccgctggcgcgattcagtcggatttgaatctgctcgcg
agcctactctaa |
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