Vibrio cholerae O1 O395: VC395_2529
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Entry
VC395_2529 CDS
T02099
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase, E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
vcr
Vibrio cholerae O1 O395
Pathway
vcr00010
Glycolysis / Gluconeogenesis
vcr00020
Citrate cycle (TCA cycle)
vcr00620
Pyruvate metabolism
vcr00785
Lipoic acid metabolism
vcr01100
Metabolic pathways
vcr01110
Biosynthesis of secondary metabolites
vcr01120
Microbial metabolism in diverse environments
vcr01200
Carbon metabolism
vcr01210
2-Oxocarboxylic acid metabolism
Module
vcr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vcr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
VC395_2529 (aceE)
00020 Citrate cycle (TCA cycle)
VC395_2529 (aceE)
00620 Pyruvate metabolism
VC395_2529 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
VC395_2529 (aceE)
Enzymes [BR:
vcr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
VC395_2529 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ACP10516
UniProt:
A0A0H3AMI2
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Position
I:complement(2669553..2672213)
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AA seq
886 aa
AA seq
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MSDMKHDVDALETQEWLAALESVVREEGVERAQYLLEQVLEKARLDGVDMPTGVTTNYIN
TIPAAQEPAYPGDTTIERRIRSIIRWNAIMIVLRASKKDLELGGHMASFQSSAAFYETCF
NHFFRAPNEKDGGDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPK
LMPEFWQFPTVSMGLGPISAIYQARFLKYLNGRGLKDTTAQRVYAFLGDGEMDEPESRGA
ISFAAREKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKL
LAKDTTGKLLQLMNETIDGDYQTFKAKDGAYVREHFFGKYPETAALVADMTDDEIFALKR
GGHESSKLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMR
NRLGLQDLISDEEVKNLPYLKLEEGSKEFEYLHARRKALHGYTPQRLPNFTGELVIPALE
EFKPLLEEQSREISSTMAYVRTLNILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYN
PHGQNYTPQDRDIVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYIYY
SMFGFQRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCISYD
PTFAYEVAVILQDGIRRMYGEQENVFYYLTLMNESYAHPAMPAGAEEGIRKGIYKLETHA
GNKAKVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNMLHPE
AEVKVPYIAQVMGTEPAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSDSRENLRRH
FEVNAGYVVVAALNELAKRGEVEKSVVAAAIKKFDIDTEKTNPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacatgaagcatgacgtagatgcactggaaactcaggagtggcttgctgccctt
gaatccgttgtccgtgaagaaggcgtagagcgtgcgcagtacctgcttgaacaagtactg
gaaaaagcgcgtttggatggggtagacatgccaacaggcgtgaccaccaactacatcaac
acgattcctgcggcgcaggagcctgcttacccaggtgacaccacgatcgaacgtcgtatc
cgttcaatcattcgctggaacgcgatcatgatcgtgctgcgtgcatcgaagaaagatctg
gaactgggtggccacatggcttctttccaatcttccgctgctttctacgaaacctgtttc
aaccacttcttccgtgctccaaacgagaaagacggtggcgacttggtttactatcaaggt
cacatctctccagggatctacgcgcgtgctttcgttgaaggccgtttgaccgaagagcaa
ctggacaacttccgtcaggaagtggatggcaaaggtcttccttcttacccacacccgaaa
ttgatgcctgaattctggcaattcccaaccgtatctatgggtctgggtccaatttctgcg
atttatcaagctcgtttcctgaagtatctgaatggtcgtggcctgaaagacaccacggca
cagcgcgtatacgccttccttggtgacggtgagatggacgagccagaatcacgcggcgcg
atctcttttgctgcgcgtgagaagctggataacctgtgcttcctgatcaactgtaacctg
caacgtctggacggccctgttatgggtaacggcaagatcatccaagaactggaaggtctg
ttccgtggcgcaggctggaacgttgtgaaagtaatctggggtaatggctgggacaaacta
ctggcgaaagataccacaggtaaactgctgcaactgatgaacgaaaccatcgacggcgac
taccaaacgttcaaagcgaaagatggcgcttacgttcgtgagcacttcttcggtaagtac
ccagagactgcagcactggttgctgacatgactgacgatgagatcttcgctctgaaacgc
ggtggtcacgaatcatctaaactgtacgcggcgttcaagaacgctcaagacaccaaaggt
cgtccaaccgttatcctagcgaaaaccgttaaaggttacggcatgggtgatgcggcagaa
ggtaagaacattgcgcaccaagtgaagaagatggatatgacccatgttctggcgatgcgt
aaccgtctaggcctgcaagatctgatctctgatgaagaagtgaagaacctgccgtacctg
aaactggaagaaggctcaaaagagtttgaatacctgcacgctcgtcgtaaagcactgcat
ggttacacacctcagcgtctacctaacttcacgggtgagttagtgatccctgcgctggaa
gagttcaagccactgctggaagagcagagtcgcgaaatttcttcaactatggcgtatgta
cgtactctgaacatcctgctgaaagataagaacattggtcaaaacatcgttcctatcatc
gcggacgaagcgcgtacgttcggtatggaaggtctgttccgtcaaatcggtatctacaac
ccgcatggtcagaactacactccacaagatcgcgatatcgtttcttactacaaagaagcg
acgtcaggtcaggtactgcaagaaggtatcaacgagctgggtgccatgtcatcttgggtt
gcggcggcaacgtcatacagcaccaacaacctgccgatgatcccgttctacatctactac
tctatgttcggtttccaacgtgttggcgacatggcgtggatggcgggcgaccaacaagcg
cgtggcttcctactgggtgctactgcgggtcgtaccacgctgaacggtgaaggtctacag
cacgaagatggtcactcgcacattctggcgggcacagtaccaaactgtatctcttacgat
ccaaccttcgcttacgaagttgcggtaatcctgcaagatggtatccgtcgcatgtacggt
gagcaagagaacgtgttctactacctgacactgatgaacgaaagctacgctcacccagca
atgcctgctggcgctgaagaaggtatccgtaaaggtatctacaagctagaaacgcacgct
ggtaacaaagcaaaagttcaactgatgagctcaggcaccatcatgaacgaagtacgtaaa
gcggcacaaattctgagtgaagagtacggcgtagcgtctgacgtttactctgtgacttca
ttcaacgagctggcgcgtgatggccaagcgtgtgatcgtttcaacatgctgcacccagaa
gcagaggtgaaagtaccttacatcgcacaagtgatgggtactgagcctgctatcgcagcg
actgactacatgaagaactacgcggatcaagtacgtgcgttcattcctgcacagtcttac
aaagtgctgggtacggatggtttcggccgctcagacagccgtgaaaacctacgtcgtcac
tttgaagtgaatgctggctacgtggtagttgcagcgctgaatgaactggcaaaacgtggt
gaagttgagaagtctgtggttgcagcagcaatcaagaaattcgacatcgatactgaaaaa
accaacccgctgtacgcttaa
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