Vibrio cholerae O49 1154-74: VAA049_481
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Entry
VAA049_481 CDS
T03828
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
vcx
Vibrio cholerae O49 1154-74
Pathway
vcx00010
Glycolysis / Gluconeogenesis
vcx00020
Citrate cycle (TCA cycle)
vcx00620
Pyruvate metabolism
vcx00785
Lipoic acid metabolism
vcx01100
Metabolic pathways
vcx01110
Biosynthesis of secondary metabolites
vcx01120
Microbial metabolism in diverse environments
vcx01200
Carbon metabolism
vcx01210
2-Oxocarboxylic acid metabolism
Module
vcx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vcx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
VAA049_481 (aceE)
00020 Citrate cycle (TCA cycle)
VAA049_481 (aceE)
00620 Pyruvate metabolism
VAA049_481 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
VAA049_481 (aceE)
Enzymes [BR:
vcx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
VAA049_481 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AKB01658
UniProt:
A0A0E4CB86
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Position
505269..507929
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AA seq
886 aa
AA seq
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MSDMKHDVDALETQEWLAALESVVREEGVERAQYLLEQVLEKARLDGVDMPTGVTTNYIN
TIPAAQEPAYPGDTTIERRIRSIIRWNAIMIVLRASKKDLELGGHMASFQSSAAFYETCF
NHFFRAPNEKDGGDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPK
LMPEFWQFPTVSMGLGPISAIYQARFLKYLNGRGLKDTTAQRVYAFLGDGEMDEPESRGA
ISFAAREKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKL
LAKDTTGKLLQLMNETIDGDYQTFKAKDGAYVREHFFGKYPETAALVADMTDDEIFALKR
GGHESSKLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMR
NRLGLQDLISDEEVKNLPYLKLEEGSKEFEYLHARRKALHGYTPQRLPNFTGELVIPALE
EFKPLLEEQSREISSTMAYVRTLNILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYN
PHGQNYTPQDRDIVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYIYY
SMFGFQRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCISYD
PTFAYEVAVILQDGIRRMYGEQENVFYYLTLMNESYAHPAMPAGAEEGIRKGIYKLETHA
GNKAKVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNMLHPE
AEVKVPYIAQVMGTEPAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSDSRENLRRH
FEVNAGYVVVAALNELAKRGEVEKSVVAAAIKKFDIDTEKTNPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacatgaagcatgacgtagatgcactggaaactcaggagtggcttgctgccctt
gaatccgttgtccgtgaagaaggcgtagagcgtgcgcagtacctgcttgaacaagtactg
gaaaaagcgcgtttggatggggtagacatgccaacaggcgtgaccaccaactacatcaac
acgattcctgcggcgcaggagcctgcttacccaggtgacaccacgatcgaacgtcgtatc
cgttcaatcattcgctggaacgcgatcatgatcgtgctgcgtgcatcgaagaaagatctg
gaactgggtggccacatggcttctttccaatcttccgctgctttctacgaaacctgtttc
aaccacttcttccgtgctccaaacgagaaagacggtggcgacttggtttactatcaaggt
cacatctctccagggatctacgcgcgtgctttcgttgaaggccgtttgaccgaagagcaa
ctggacaacttccgtcaggaagtggatggcaaaggtcttccttcttacccacacccgaaa
ttgatgcctgaattctggcaattcccaaccgtatctatgggtctgggtccaatttctgcg
atttatcaagctcgtttcctgaagtatctgaatggtcgtggcctgaaagacaccacggca
cagcgcgtatacgccttccttggtgacggtgagatggacgagccagaatcacgcggcgcg
atctcttttgctgcgcgtgagaagctggataacctatgcttcctgatcaactgtaacctg
caacgtctggacggccctgttatgggtaacggcaagatcatccaagaactggaaggtctg
ttccgtggcgcaggctggaacgttgtgaaagtgatctggggtaatggctgggacaaacta
ctggcgaaagataccacaggtaaactgctgcaactgatgaacgaaaccatcgacggcgac
taccaaacgttcaaagcgaaagatggcgcttacgttcgtgagcacttcttcggtaagtac
ccagagactgcagcactggttgctgacatgactgacgatgagatcttcgctctgaaacgc
ggtggtcacgaatcatctaaactgtacgcggcgttcaagaacgctcaagacaccaaaggt
cgtccaaccgttatcctagcgaaaaccgttaaaggttacggcatgggtgatgcggcagaa
ggtaagaacattgcgcaccaagtgaagaagatggatatgacccatgttctggcgatgcgt
aaccgtctaggcctgcaagatctgatctctgatgaagaagtgaagaacctgccgtacctg
aaactggaagaaggctcaaaagagtttgaatacctgcacgctcgtcgtaaagcgctgcac
ggttacacgcctcagcgtctacctaacttcacgggtgagttagtgatccctgcgctggaa
gagttcaagccactgctggaagagcagagccgcgaaatttcttcaactatggcgtatgta
cgtactctgaacatcctgctgaaagataagaacattggtcaaaacatcgttcctatcatc
gcggacgaagcgcgtacgttcggtatggaaggtctgttccgtcaaatcggtatctacaac
ccgcacggtcagaactacactccacaagatcgcgatatcgtttcttactacaaagaagcg
acgtcaggtcaggtactgcaagaaggtatcaacgagctgggtgctatgtcatcttgggtt
gcggcggcaacgtcatacagcaccaacaacctgccgatgatcccgttctacatctactac
tctatgttcggtttccaacgtgttggcgacatggcgtggatggcgggtgaccaacaagcg
cgtggcttcctactgggtgctactgcaggtcgtaccacgctgaacggtgaaggtctacag
cacgaagatggtcactcgcacattctggcgggcacagtaccaaactgtatctcttacgat
ccaaccttcgcttacgaagttgcggtaatcctgcaagacggtatccgtcgtatgtacggt
gagcaagagaacgtgttctactatctgacactgatgaacgaaagctacgctcacccagca
atgcctgctggcgctgaagaaggtatccgtaaaggtatctacaagctagaaacgcacgct
ggtaacaaagcaaaagttcaactgatgagctcaggcaccatcatgaacgaagtacgtaaa
gcggcacaaattctgagtgaagagtacggcgtagcgtctgacgtttactctgtgacttca
ttcaacgagctggcgcgtgatggtcaagcgtgtgatcgtttcaacatgctgcacccagaa
gcagaagtgaaagtaccttacatcgcacaagtgatggggactgagcctgctatcgcagcg
actgactacatgaagaactacgcggatcaagtacgtgcgttcattcctgcacagtcttac
aaagtgctgggtacggatggtttcggccgctcagatagccgtgaaaacctacgtcgtcac
tttgaagtgaatgctggctacgtggtagttgcagcgctgaatgaactggcaaaacggggt
gaggttgagaagtctgtggttgcagcagcaatcaagaaattcgacatcgacactgaaaaa
accaacccgctgtacgcttaa
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