Aliivibrio fischeri ES114: VF_0337
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Entry
VF_0337 CDS
T00236
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
vfi
Aliivibrio fischeri ES114
Pathway
vfi00270
Cysteine and methionine metabolism
vfi00450
Selenocompound metabolism
vfi00670
One carbon pool by folate
vfi01100
Metabolic pathways
vfi01110
Biosynthesis of secondary metabolites
vfi01230
Biosynthesis of amino acids
vfi04981
Folate transport and metabolism
Module
vfi_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
vfi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
VF_0337 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
VF_0337 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
VF_0337 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
VF_0337 (metH)
04980 Cobalamin transport and metabolism
VF_0337 (metH)
Enzymes [BR:
vfi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
VF_0337 (metH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AAW84832
UniProt:
Q5E814
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Position
I:359759..363439
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AA seq
1226 aa
AA seq
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MAGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVL
SQPQIIRDIHEAYLEAGADILETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKW
TEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYSESTRALIRGGSDLI
LIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHV
KPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEW
ASSGFLNLIGGCCGTTPEHIRQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFIN
VGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQIIDINMDEGMLDAEACMVRFLN
LCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGA
AVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNY
AVDFIEAVGDIKRTLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVN
AGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEYLERAVGKVEDKSALEWRDWP
VEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQV
VKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEII
DLGVMVSCETILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTS
KAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPSFVEKLDIDYERVREQHSRKQ
PRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLV
GKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDE
SRTKVAKVLHNLRQQTEKPKGFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYK
ANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPNETLSNDDLIREKYQGIRPAP
GYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQ
DQAESYADRKGWNMLEAEKWLGPNLN
NT seq
3681 nt
NT seq
+upstream
nt +downstream
nt
gtggcaggaagcaatataaaagtacaaatagaaaagcaactttcagagcgaattttattg
attgatggtggtatgggcaccatgattcaaggttataagtttgaagaggaagattataga
ggggaacgttttaataaatggcattgtgatcttaaaggtaacaatgatttattagttctt
tcacaaccacaaattataagagatatccacgaagcctatttagaagctggtgctgatatc
cttgagactaatacttttaatgcaacaactattgctatggctgattatgatatggaaagc
cttagtgaagagattaactttgaagcagcaaagcttgctcgtgaagttgcagataaatgg
accgagaagacaccaaataagcctcgttatgtcgcaggagtgcttggaccaacaaaccga
acttgttctatttctccagatgtaaatgatccaggctttcgtaatgtatcgtttgatgaa
ttagtggaagcttattcagagtcaactcgagcacttattagaggtggctcagatcttatt
cttatcgaaactatttttgatacattaaatgctaaagcgtgttcttttgctgtcgagtct
gtttttgaagagcttgatattactctgcccgttatgatttcagggacaattactgacgca
tcaggaagaaccttatcgggacaaacaacagaagctttttataatgcattaagacatgta
aaacctatttcttttggtcttaattgtgcgcttggtcctgatgaattacgtgaatatgta
agcgatctttcacgtatttctgaatgttatgtttctgctcacccaaacgctggtttacct
aatgcatttggtgagtatgatttatcccctgaagatatggctgagcatgttgcggaatgg
gcaagtagcggatttttaaatctcattggtggatgttgtggcaccactcctgaacatatt
cgtcaaatggctttagttgttgaaggtgtgaaacctcgacaattacctgaattacccgtc
gcttgtcgtctttccggattagagcctttaacaatagaaaaagattctttgtttattaat
gttggtgaacgtacaaatgttactggatctgctcgttttaaacgcttaattaaagaagag
ctttatgatgaagcactaagtgttgctcaagagcaagttgaaaacggtgctcaaattatc
gatatcaacatggatgaaggcatgcttgatgctgaagcatgtatggttcgttttttaaat
ctttgtgcatcagagcctgaaatatctaaagttccagtgatggttgattcttctaaatgg
gaagtaattgaagctggattaaagtgtattcaaggtaaggggatagttaattcaatctct
ttaaaggaaggcaaagaaaagtttgtacatcaagccaagttaatacgtcgctatggtgct
gcagtgatcgttatggcttttgatgaagtcggccaagcggacactcgtgagcgtaaaatt
gaaatttgtaccaatgcctacaatattttagttgatgaagttggtttcccacctgaagat
attatttttgatcctaatatttttgcggttgctacaggtatcgatgagcataataactat
gcagtagactttattgaagctgttggtgatataaagcgaactcttcctcatgcaatgatt
tcaggtggtgtttctaacgtctctttttctttccgtggaaataactacgttcgtgaagct
atccatgccgtatttttatatcactgttttaaaaatggtatggatatgggtatcgtaaat
gcaggacagttggaaatatacgataacgtaccagaagatttgcgtgaagcggttgaagat
gtagttctgaatcgtagagatgattctacggaacgtttacttgatattgcaactgagtat
ttagaacgagctgttggtaaagttgaagataaatcagctttagagtggcgtgattggcct
gttgaaaaacgtcttgaacattctctagtgaaggggataacagagtttattgtcgaagat
acagaagaagctcgaatcaatgcagaaaaaccaatagaagtaattgaagggccattgatg
gacggaatgaacgtcgtcggtgatctttttggtgaaggaaaaatgttccttcctcaagta
gtaaagtctgctcgtgtaatgaaacaagcagttgctcatttagaaccgtttattaatgcg
tccaaagaagttggagcaacaaatggaaaaatacttttagcaacggtaaaaggggatgtt
catgatattggtaagaatatcgttggcgttgttttacagtgtaataattatgagataatt
gatcttggtgtcatggtctcttgtgaaactatcttaaaagtagccaaagaagaaaatgta
gacatcattggtttatctggattgataacaccatcattagatgaaatggtccatgttgct
aaagagatggaacgacaagggttcgatttaccactattgattggtggggcaacaacttca
aaagcacatacagcggtaaaaattgaacaaaactattctcaacctgttgtgtatgtcaac
aatgcttctcgagctgtaggtgtctgtacgtcactactttccgatgaactaaaaccttct
ttcgttgagaagctagatattgattacgaacgagttagagagcagcatagtcgtaaacaa
ccgcgaactaagcctgtgactttagaggttgctcgagcgaataaagttgctattgactgg
gcttcttatacacctcctgtcccactgaagcctggtgtacatatatttgataattttgat
gtttcaacattgcgtaattatattgattggaccccattttttatgacttggtctcttgtt
gggaaatacccaaagatcttagatcatgaagaagtaggtgaagaagccaaacgattattt
aaagatgcaaatgatctattagatcgagttgaaaaagaagggttacttaaagcccgtgga
atgtgtgcgctatttccagcttctagtgttggtgatgatattgaagtttatactgatgaa
tcacgcactaaagttgcaaaagtacttcacaatttgcgacaacaaacggagaaaccgaaa
ggttttaactactgtttatctgattatatagcccccaaagaatcgggtaaaaatgattgg
atcggtggttttgctgtaactggtggtattggtgagcgtgaactagccgatgaatataaa
gcaaatggtgatgattataacgctatcatgattcaagcggtggctgatcgtctagctgaa
gcctttgctgaatatttacatgaaaaagtacgtaaagaaatttggggttactctcctaat
gagacactttcaaatgacgatttaatccgtgagaaataccaaggtattcgtcctgctcct
ggttacccagcttgtcctgaacatacagaaaaaggggctttatgggagctaatgaatgtt
gaagaatctattggaatgtctttaacatcaagctatgcaatgtggcccggtgcatctgtg
tcaggaatgtatttttcacatccggattctcgttattttgcgattgctcagattcagcaa
gatcaagccgaaagctatgccgatcgtaaaggttggaatatgcttgaagctgagaagtgg
ttaggtccaaatttgaattaa
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