KEGG   Varanus komodoensis (Komodo dragon): 123017589
Entry
123017589         CDS       T07701                                 
Symbol
MAP2K2
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2 isoform X1
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
vko  Varanus komodoensis (Komodo dragon)
Pathway
vko04010  MAPK signaling pathway
vko04012  ErbB signaling pathway
vko04068  FoxO signaling pathway
vko04140  Autophagy - animal
vko04148  Efferocytosis
vko04150  mTOR signaling pathway
vko04210  Apoptosis
vko04218  Cellular senescence
vko04270  Vascular smooth muscle contraction
vko04370  VEGF signaling pathway
vko04371  Apelin signaling pathway
vko04517  IgSF CAM signaling
vko04519  Cadherin signaling
vko04540  Gap junction
vko04620  Toll-like receptor signaling pathway
vko04810  Regulation of actin cytoskeleton
vko04910  Insulin signaling pathway
vko04912  GnRH signaling pathway
vko04916  Melanogenesis
vko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:vko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123017589 (MAP2K2)
   04012 ErbB signaling pathway
    123017589 (MAP2K2)
   04370 VEGF signaling pathway
    123017589 (MAP2K2)
   04371 Apelin signaling pathway
    123017589 (MAP2K2)
   04068 FoxO signaling pathway
    123017589 (MAP2K2)
   04150 mTOR signaling pathway
    123017589 (MAP2K2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123017589 (MAP2K2)
   04519 Cadherin signaling
    123017589 (MAP2K2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123017589 (MAP2K2)
   04148 Efferocytosis
    123017589 (MAP2K2)
  09143 Cell growth and death
   04210 Apoptosis
    123017589 (MAP2K2)
   04218 Cellular senescence
    123017589 (MAP2K2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    123017589 (MAP2K2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123017589 (MAP2K2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123017589 (MAP2K2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123017589 (MAP2K2)
   04912 GnRH signaling pathway
    123017589 (MAP2K2)
   04916 Melanogenesis
    123017589 (MAP2K2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    123017589 (MAP2K2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123017589 (MAP2K2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vko01001]
    123017589 (MAP2K2)
Enzymes [BR:vko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123017589 (MAP2K2)
Protein kinases [BR:vko01001]
 Serine/threonine kinases: STE group
  STE7 family
   123017589 (MAP2K2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 APH
Other DBs
NCBI-GeneID: 123017589
NCBI-ProteinID: XP_044274965
Ensembl: ENSVKKG00000007904
UniProt: A0A8D2KW12
LinkDB
Position
Unknown
AA seq 402 aa
MPAKRKLVPPALNITPTIAEGPSPTGGEGDGSEAHLVDLQKKLEELELDEQQRKRLEAFL
TQKAKVGELKDDDFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRE
LQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVL
RGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPER
LQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEAIFGRPMVDGAEGEPHSISPRP
RPPGRPISGHGIDSRPAMAIFELLDYIVNEPPPKLPTGVFTQDFQEFVNKCLIKNPAERA
DLKMLMNHAFIKRSEVEDVDFAGWLCKTLRLNQPGTPTRTAM
NT seq 1209 nt   +upstreamnt  +downstreamnt
atgccggccaaaaggaagctggtgccgccggccctcaacattacccccaccatagcggag
gggcccagccccactggcggggagggcgacggctccgaagcacatctagttgacctccag
aagaaactggaagagctggagctggatgagcagcaaaggaagcggttggaggctttcctc
actcagaaagccaaagttggagagctgaaagatgatgactttgagaggatttcggaactg
ggtgctgggaacggcggagtggtcaccaaagtacaacacaaaccctcagggctaatcatg
gcacggaagctgattcacttggagatcaaacctgccatccggaaccagatcatccgagag
ctccaggtgcttcatgagtgcaactccccgtacattgtgggtttctatggcgccttttac
agtgatggggagatcagcatctgcatggaacatatggacggaggctccctagaccaggtt
ctgaaagaagccaagagaattcctgaggaaatcttggggaaagtcagcattgcggttttg
cgagggttggcttatcttcgagagaagcaccagatcatgcacagagatgtgaagccttct
aatatcttggtgaattctcggggagagatcaaactctgtgattttggggtcagcggccag
ctcattgactccatggctaattccttcgtgggcacgcgatcctatatgtctcctgagcgt
ttacaaggcactcactactcggtgcagtctgatatctggagcatgggcctctccctggtg
gagctgtcgatcggaaggtaccccatccccccgccagatgccaaggaactggaagcgata
tttggccgccccatggtcgatggggcagaaggggaaccccacagcatttcgccacggccc
aggccccctggacggcccattagcggacatggcatagatagtcgacctgcaatggccatc
tttgaattgctggactacattgttaatgagccacctccaaagctgccgacaggggtattc
actcaagatttccaggagtttgtaaataaatgcttgatcaaaaaccctgctgaaagggca
gacctaaagatgctgatgaatcacgcctttatcaaacgttctgaggtggaagatgtggat
ttcgcaggctggctatgtaagacgctgcggttgaaccagcctggcacgcccacccgcact
gccatgtga

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