KEGG Orthology (KO) [BR:vko00001]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
123032045
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:vko00199]
123032045
Enzymes [BR:vko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.25 cholesterol 24-hydroxylase
123032045
Cytochrome P450 [BR:vko00199]
Cytochrome P450, animal type
CYP46 family
123032045
362 aa
MDPAFSRSYLIGLMGTFNEQAEELMMELEKKADGETAVDVMDLLRRVTLDIIAKAAFGLE
LNTLHDDRTAFPQAVTMIMKGIGAARRPFFRYLPWNRKVVKEVQESVRLLRRIGKECIEQ
RHKAIRNGEEVPLDILTQILKGAAQEKDCDDENMLDNFVTFFVAGHETTANQLSFTVMEL
TRHPDIITKLQAEVDEVIGVKRDITYEDLGKLEYLSQVLKEILRLYPPVPGTVRWTGKEN
VIEGVYIPANSTIIFNTYLMGHMERYFKDPEVFNPDRFRKDQPRPYFSYFPFSLGSRSCI
GQVFSQMEAKVVMAKFLQRFEFELVPPQSFKILETGTLRPLDAVVCRLKLRHQLGCNSEM
KY
