KEGG   Varanus komodoensis (Komodo dragon): 123033249
Entry
123033249         CDS       T07701                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like isoform X1
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
vko  Varanus komodoensis (Komodo dragon)
Pathway
vko00140  Steroid hormone biosynthesis
vko01100  Metabolic pathways
Module
vko_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
vko_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
vko_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:vko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    123033249
Enzymes [BR:vko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     123033249
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     123033249
SSDB
Motif
Pfam: 3Beta_HSD Epimerase GDP_Man_Dehyd NAD_binding_4 Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 NmrA KR adh_short
Other DBs
NCBI-GeneID: 123033249
NCBI-ProteinID: XP_044305695
Ensembl: ENSVKKG00000002367
UniProt: A0A8D2KRN3
LinkDB
Position
Unknown
AA seq 410 aa
MSLDQEHIKRLICLIDSTVKQRRKGYPCKELSLSTMSLAGMRCLVTGAGGFLGERIVCQL
LEEDSLAEVRGLDKAVSSEALQNFGKVKTKTLLTLMQGDIRDEALLQKAVQDITLVIHAA
CILDPMGAVDTHTLWDVNVRGTQLLLDTCLHNDVPYFIYTSSLEVTGPNTRGDPIYDGDE
DTVYQNTKGFLYAESKKEAEKCVLAMNNQVLKDGKSFVTCSLRPMYIYGEGSPFLLQHLD
ESIRNNNVFLRLSRKEALVNPVYVGNAAWAHIQMAKAMVDPQKVKQVQGCFYYISDDTPH
LSYSDLNYELTKELGFRIESRLPMPLMMLYCYALLLETIRFLLQPFVRYVPHINHHLLTL
LNTPFSFSYRKAQRDFGYVPRYKWKEAKQHTSQWYAEVIPQRTAFLKGNH
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgagcttagaccaggaacacatcaaaagactcatttgcttaattgactccacagtaaag
cagagaaggaagggctacccttgcaaggaactctcgctttctaccatgtccttagcagga
atgaggtgtctggtgacaggagctggtgggtttcttggtgaaaggatagtttgccagctg
ctggaagaagacagcctagctgaggtccgaggtttggacaaagcagtcagctctgaggca
ctgcagaattttggaaaagtgaagactaagactctcctgacgctcatgcaaggggatatc
cgtgatgaggcacttcttcaaaaagctgtccaggatatcaccctcgtcatccatgcagct
tgcatccttgaccctatgggagctgtagacacacacacactctgggacgtcaatgtcaga
ggtacacagctgctgctagacacctgccttcacaacgatgtcccgtattttatctatacc
agcagccttgaagtgacaggtccaaacacaagaggtgaccccatctatgatggtgatgaa
gacacagtctatcagaacaccaaaggatttctttatgctgagagtaagaaagaggcagag
aaatgtgtattagcaatgaataaccaagtgctgaaggatggcaagagctttgtgacatgt
tctttgaggcccatgtacatttacggagaggggagtccttttcttctgcagcatctggat
gaaagcatccgaaacaataacgtctttttgaggctctccaggaaggaggctcttgtaaat
ccagtctatgtagggaatgctgcttgggctcacattcaaatggctaaagccatggtggac
ccccaaaaggtcaaacaggtccaagggtgcttctattacatcagcgatgatactccccac
ctgagttactcagatcttaattatgagctaaccaaggagctgggctttcgtattgaatcc
aggttgcccatgcctctgatgatgctctattgctatgctctgttgctggagacgatacgc
ttcttactccagccttttgtgcggtatgttccccacatcaatcatcaccttctgactttg
ctcaacaccccattcagcttttcttacaggaaagcccaaagggattttggctacgtgccc
cggtacaaatggaaggaagccaagcagcataccagccagtggtatgctgaagtaattcca
cagagaacagctttcctgaaaggcaaccactga

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