Vulpes lagopus (Arctic fox): 121472899
Help
Entry
121472899 CDS
T07435
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg01524
Platinum drug resistance
vlg03440
Homologous recombination
vlg03460
Fanconi anemia pathway
vlg04120
Ubiquitin mediated proteolysis
vlg04151
PI3K-Akt signaling pathway
vlg05206
MicroRNAs in cancer
vlg05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
121472899 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
121472899 (BRCA1)
03460 Fanconi anemia pathway
121472899 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
121472899 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
121472899 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
121472899 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
121472899 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
vlg01009
]
121472899 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
vlg04121
]
121472899 (BRCA1)
03036 Chromosome and associated proteins [BR:
vlg03036
]
121472899 (BRCA1)
03400 DNA repair and recombination proteins [BR:
vlg03400
]
121472899 (BRCA1)
Enzymes [BR:
vlg01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
121472899 (BRCA1)
Protein phosphatases and associated proteins [BR:
vlg01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
121472899 (BRCA1)
Ubiquitin system [BR:
vlg04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
121472899 (BRCA1)
Multi subunit type E3
BRCC complex
121472899 (BRCA1)
Chromosome and associated proteins [BR:
vlg03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
121472899 (BRCA1)
DNA repair and recombination proteins [BR:
vlg03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
121472899 (BRCA1)
BRCA1-A complex
121472899 (BRCA1)
BRCA1-B complex
121472899 (BRCA1)
BRCA1-C complex
121472899 (BRCA1)
BRCA complex
121472899 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
121472899 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_3
zf-RING_UBOX
zf-C3HC4_4
zf-RING_5
zf-RING_2
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
zf-rbx1
DUF5630
Baculo_IE-1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
121472899
NCBI-ProteinID:
XP_041580467
LinkDB
All DBs
Position
12:complement(41469009..41536114)
Genome browser
AA seq
1878 aa
AA seq
DB search
MDLSADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFADSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPTLETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYIE
LGSDSSEDTVNKASSCSVGDDKLEITSQGARAEASLNPAKKAACEFSEDITNIEHHQSGN
KDLTTTEKHATKKHPEKYQGISVSNLHVEPCGTNTHASSLQHENSSLLLTKHRMNVEKAE
ICNNSKQPGLARSQQSRWAESKETCNDRQTPSTEKKVVVNANLLCGRKELNKQKPPRSDS
PRDSQDVPWITLNSSIRKVNEWFSRSDEILTSDDSHDRGSELNTEVGGAEVPNEVGEYSG
SSEKIDLMASDPQDALICESERVHTKPVGSNIEDKIFGKTYRRKASLRKVSHTFRTEVLT
IGACAIEPQTMQTHPLMNKAEHKRKTTSSLHPEDFIKKVELGIVPKTPEKLIEGINQIKR
DGHVTNITNNGPENETEGDYVQKEKNPNPTESLEKESAFRTKTEPMSSRISNMELELDSS
SSKAPKKNRLRRKSSARHTCALEFVVNRNLNPPDHSELQIESCSSSEEMKKQHLDQVPVR
HNKTLQLMQDKEPAGRAKKSSKPGEQINKRLASHAFPELTLTNVSGFFANCSSSSKPQEY
INPGLRREEIEESRRMTQVSDSTRDPKELVLSGGRGLQTERSVESTSISLVLDTDYGTQD
SISLLEADTLRKAKTAPNQWANLCATIENPKEPIHGCSKDTRNDTEGFVVPLTCEDNHTQ
ETSIEMEESELDTQCLRNMFKVSKRQSFALFSYPRDPEEDCVTVCPRSGAFGKQGPKVTL
ECGQKEESQGKKESEIRHVQAVHTTAGFSAVSQKPKKPGDFAKCSIKGVSRLCLSSQFKG
KETELLIANYHGISQNPYHIPPLSPIRSCVKTLCQENLSEEKFEQHSVSPERAVGNERVI
QSTVSTISQNNIRECASKEVGSSSVNEVVSSTNEVGSSINEVGSSGENIQAELGRNRGPK
LNAMLRLGLMQPEVCKQSLSLSNCKHPEMKWQGQSEGAVLSVSADFSPCLISDNPEQPMG
SSRSSQVCSETPDDLLNGDKIKGKVSFAESDIKERSAVFSKSVQSGEFSRSPSPSDHTRL
AQGYQRGAKKLESSEENMSSEEEELPCFQHLLFGKVTNMPSQSTSHNAVAAEGLSNKTEE
NLDSLKNSLSDVSNQVPSAKASQEHHLSEEARCSGSLFSSQCSALEDLTVNTNNQDPFSM
FDPPSKQVRHQSENLDVLNDKELVSDDDDEREPGLEEESPQEEQSVDSDLGEVASGYESE
TSLSEDCSRLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPSLIAD
SCSPEDLLNPEQSASERVLTSEKSSDSPISQNPESLSTDKFQVFLDSSTSKNGEPGMIRS
SPSQSRSLDSRWYVHSCPRSLQDTNCPSQKELTKVVCMEEQQPTESEARDLMEQSYLSRP
DLEGAPYLESGISLFSDDPESDPSSHRASELVHVSSMPTSTSALKLRQFQVKESGKSTAV
HIASTAGYNKSEYSVGREKPEVMSSTRGVNKRISMVASGLTPKEFMLVHKFARKHHITLT
NLISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKILDEHDFEVR
GDVVNGRNHQGPKRARESQDRESQDRKIFRGLEICCYGPFTNMPTDQLEWMVHLCGASVV
KEPSLFTLSKGTHPVVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQKLDT
YLIPQIPRAAADSSQPCV
NT seq
5637 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcggatcgtgttgaggaagtacaaaatgttcttaatgctatgcagaaa
atcttagagtgtccaatatgtctggagttgatcaaagagcctgtttctacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaggaaggggccttcacag
tgtcctttgtgtaagaacgatataaccaaaaggagcctacaagaaagtacaagatttagt
caacttgttgaagagttgttgaaaatcattcatgcttttgagctggacacaggattgcag
tttgcagacagctataacttttccaaaaaggaaaataactctcctgagcatctaaaggag
gaagtttctattatccaaagtatgggctatcgaaaccgtgccaaaagacttcgacagagt
gaacctgaaaaccctaccttggaaaccagtcttagtgtccaactctctaaccttggaatt
gtgcgatctctgagaacaaagcagcagatacagcctcagaataagtctgtctacattgaa
ttggggtctgattcttctgaagatacagttaataaggcaagttcttgcagtgtgggagat
gacaagttagaaatcacctctcaaggagccagggctgaagccagtttgaatcctgcaaaa
aaggctgcttgtgaattttctgaggacataacaaatattgaacatcatcaatccggtaat
aaagatttgaccaccactgagaagcatgcaactaagaagcatccagaaaagtatcagggt
atttctgtttcaaacttgcatgtggagccatgtggcacaaatactcatgccagctcatta
cagcatgagaacagcagtttattactcactaaacacagaatgaatgtagaaaaggctgaa
atctgtaataacagcaaacagcctggcttagcaaggagccaacagagcagatgggctgaa
agtaaggaaacatgtaatgataggcagactcccagcacagagaaaaaggtagttgtgaat
gctaatctcctgtgtgggagaaaagaactgaataaacagaaacctccacgctctgacagt
cctagagattcccaagatgttccttggataacactgaatagtagcatacggaaagttaat
gagtggttttccagaagtgatgaaatattaacttctgatgattcacatgacagaggatct
gaattgaatactgaagtaggtggtgcagaagttccaaatgaagtgggtgaatattctggt
tcttctgagaaaatagacttaatggccagtgatcctcaggatgctttgatatgtgaaagt
gaaagagtccacaccaagccagtaggaagtaatatcgaagataaaatatttggaaaaacc
tatcggaggaaggcaagcctccgtaaggtgagccacacctttagaactgaagttctaact
ataggagcgtgtgctatagaacctcagacaatgcaaacccatcccctcatgaataaagca
gagcataaaaggaaaactacatctagccttcatcctgaggattttatcaagaaagtagag
ttaggcattgttccaaagactcctgaaaagctaattgagggaatcaaccaaatcaagcga
gatggtcatgtgacaaatattacaaataatggtcctgagaatgaaacagaaggtgattat
gttcagaaagagaaaaatcctaacccaacagaatcattggaaaaagaatctgcttttaga
accaaaactgaaccaatgagcagcaggataagcaatatggaactggaattagatagctcc
agttcaaaagcacctaagaagaacaggctgaggaggaagtcctctgccaggcacacttgt
gcccttgaattcgtagtcaatagaaatctaaacccacctgatcatagtgaactacagatt
gaaagttgttctagcagtgaagagatgaaaaaacagcatttggaccaagtaccagtcaga
cacaacaaaacacttcagctcatgcaagataaagaacctgcaggtagagctaagaaaagt
agtaagccaggagaacaaataaataagagactcgccagtcatgcttttccagagctaact
ttaacaaacgtatctggtttttttgctaactgttcaagttctagtaagcctcaagagtac
atcaaccctggccttcgaagagaagaaatagaagagagccgaagaatgactcaagtgtct
gatagtaccagagatcccaaagagctggtattgagtggaggaagaggtttgcaaactgag
agatctgtagagagtaccagtatctcattggtacttgatactgattatggtacacaggac
agtatctcattactggaagctgacaccctgaggaaggcaaaaacagcaccaaatcaatgg
gcgaatctgtgtgcaacaattgagaaccccaaggaacctatccatggttgttctaaggac
actagaaatgacacagagggttttgtagttccattgacgtgcgaagataaccacactcag
gagacaagcatagaaatggaagagagtgaacttgacacgcagtgcttacgcaatatgttc
aaggtttcaaagcgtcagtcatttgctctgttttcatatccaagagatccggaagaggac
tgtgtaacagtctgtccccgctctggggcctttggaaaacaaggtccaaaagtcactcta
gaatgtggacagaaggaagaaagtcagggaaagaaagagtctgaaatcagacatgtgcag
gcagttcatacaactgcaggcttttctgcagttagtcagaaacctaagaagccaggcgat
tttgccaaatgtagcataaagggagtctctcggctttgtctgtcatctcagttcaaaggc
aaggaaactgaactccttattgcaaattaccatggaatttcccaaaacccttatcatata
ccaccactttctcccatcagatcatgtgttaaaactctatgtcaggaaaacctgtcagag
gaaaagtttgagcaacattcagtgtcacccgaaagagcagtgggaaatgagagagtcatt
caaagtacagtgagcacaattagccaaaataacattagagaatgtgcttctaaagaagtc
ggctcaagcagtgttaatgaagtagtttccagtactaatgaagtaggctctagtattaat
gaagtgggttccagtggtgaaaacattcaagcagaactaggtagaaaccgaggacctaaa
ttaaatgctatgctcagattaggtcttatgcaacctgaagtctgtaagcaaagcctttct
ttaagtaattgtaaacatccagaaatgaaatggcaaggacaaagtgaaggagcagttctg
tctgttagtgcagatttctctccatgtctgatttcagataacccagaacaacctatggga
agtagtcggtcttctcaggtttgttctgagacacctgatgacctattaaatggtgacaaa
ataaagggaaaagtcagctttgctgaaagtgacattaaggaaagatctgctgtgtttagc
aaaagtgtccagagtggagagttcagcagaagccctagcccttcagaccatacacgtttg
gcccagggttaccagagaggggccaagaaattagagtcctcagaagagaacatgtctagt
gaggaggaagagcttccctgcttccaacacttactatttggtaaagtaaccaacatgcct
tctcagtctaccagtcacaatgcagttgccgcagagggtctatctaacaaaacagaggag
aacctagactcattgaagaatagtttaagtgatgtcagtaaccaggtaccgtcagcaaag
gcatcccaggaacatcaccttagtgaggaagcaagatgttctggcagcttattttcttca
cagtgcagtgctttggaagacttgactgtaaatacaaataaccaggatcctttctcgatg
tttgatcctccttccaaacaagtgaggcatcaatctgaaaatctggacgttctgaatgac
aaggaattggtttcagatgatgatgatgaaagggaacctggcctggaagaggaaagtcct
caagaagagcagagtgtggattcagacttaggtgaagtggcatctggatatgagagtgaa
acgagcctctctgaagactgttccaggttgtcctctcagagtgatattttaaccactcag
cagagagataccatgcaagataacctgataaagctccagcaggaaatggctgaactggaa
gctgtgttagagcagcatgagagccagccctctaacagctccccttcccttatagcagat
tcttgttcgcctgaggatctgctgaatccggaacaaagcgcatcagaaagagtattaact
tcagagaaaagtagtgactctcctataagccaaaatcccgaaagcctttctactgacaaa
tttcaagtatttctggatagttccaccagtaaaaatggagaaccaggaatgatacggtct
tccccttcacagtcccggtcgttagatagtaggtggtatgtacacagctgcccaaggagt
cttcaggacactaactgcccatctcagaaggagctcactaaggttgtctgtatggaggag
caacaaccaactgagtcagaagcaagagatctcatggagcaatcttatttgtcaagacca
gatctggagggagccccttacctcgaatctggaatcagccttttctctgatgaccctgag
tctgatccctcgtcacacagagcctcagagctggttcatgttagcagcatgccaacttca
acctctgcgttgaaattacgccaatttcaggtcaaagaatcaggcaagagtacagctgtc
catattgctagtactgctgggtataataagagcgaatacagtgtgggcagagaaaagcca
gaagtgatgtcttcaacaagaggagtcaacaaaagaatatctatggtggcatcaggcttg
accccaaaagaatttatgcttgtgcacaagtttgccagaaaacaccacatcactttaact
aatctaatatctgaagagacaacacatgtcattatgaaaacagatgctgagtttgtgtgc
gaacgaacactgaaatattttctgggtattgcaggaggaaaatgggtagttagctatttc
tgggtaacccagtctattaaagaaagaaagatactagatgagcatgattttgaagtcaga
ggagatgttgtgaatggaagaaatcaccagggtccgaagcgagcaagagaatcccaggac
agagaatcccaagacagaaagatcttcaggggcctagaaatctgttgctatggacccttt
accaacatgcccacagatcaattagagtggatggtgcacctctgtggggcttctgtggtg
aaggagccttcgttattcaccctcagcaagggcactcatccagtggtagtcgtgcagccg
gatgcctggacagaggacagtggcttccatgcgattgggcagatgtgtgaggcacctgtg
gtgacccgagagtgggtactggacagtgtagccctctaccagtgccagaagctggacacc
tacctgatcccacagattcccagagctgctgcagactccagccagccatgcgtgtaa
DBGET
integrated database retrieval system
