Vulpes lagopus (Arctic fox): 121494166 Help Entry 121494166         CDS       T07435                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg04062   Chemokine signaling pathway vlg04151   PI3K-Akt signaling pathway vlg04217   Necroptosis vlg04550   Signaling pathways regulating pluripotency of stem cells vlg04630   JAK-STAT signaling pathway vlg04658   Th1 and Th2 cell differentiation vlg04659   Th17 cell differentiation vlg05161   Hepatitis B vlg05162   Measles vlg05166   Human T-cell leukemia virus 1 infection vlg05169   Epstein-Barr virus infection vlg05200   Pathways in cancer vlg05203   Viral carcinogenesis vlg05223   Non-small cell lung cancer vlg05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:vlg00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     121494166 (JAK3)    04151 PI3K-Akt signaling pathway     121494166 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     121494166 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     121494166 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     121494166 (JAK3)    04659 Th17 cell differentiation     121494166 (JAK3)    04062 Chemokine signaling pathway     121494166 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121494166 (JAK3)    05203 Viral carcinogenesis     121494166 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     121494166 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121494166 (JAK3)    05161 Hepatitis B     121494166 (JAK3)    05162 Measles     121494166 (JAK3)    05169 Epstein-Barr virus infection     121494166 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     121494166 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:vlg01001]     121494166 (JAK3) Enzymes [BR:vlg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      121494166 (JAK3) Protein kinases [BR:vlg01001]  Non-receptor tyrosine kinases   JAK family [OT]    121494166 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl Kdo ABC1 FERM_C_FAK1 Haspin_kinase FERM_M SH2 Motif Other DBs NCBI-GeneID:  121494166 NCBI-ProteinID:  XP_041616280 LinkDB All DBs Position 7:complement(13054422..13073048) Genome browser AA seq 1106 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA SGILPVYHSLFALATEDLSCWFPPSHIFSVEDSGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQQ PEELLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRTVRRALRRVTACQADRHSLMAKYIM DLERLDPARAVETFLVSFPGAAGGQDAQGLLRVAGDLGIAWSPGGQEALQPFCDFPEIVD ISIKQAPRAGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLTACWDGGLHMDGAALNLTFCCTPRPK EKSNLIVVRRGCSLPTSSPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEVVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GIPMPISTLDPAKKLQFYEERQQLPAPKWMELAVLIQQCMVYEPGQRPSFRAIIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDAGRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYGNKSCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPNDRPTFSALGPQLDALWSGGRGVA NT seq 3321 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagcgaggagacgcccctgatcccccagcgttcctgcagcctctcgtct tcagaggctggtgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc ctatccttctcctttggggaccattcagctgaagagctctgtgtctgggctgctaaggcc agtggcatcctgcctgtgtaccactccctctttgctctggccaccgaggacctgtcctgc tggttccccccgagccacatcttctccgtggaggactccggcacccaagtcctggtctac aggctccgcttttacttccccaactggtttgggctagagaagtgccaccgattcgggcta cgaaaggacttggccagtgccatccttgacctgccagtcctggagcacctctttgcccag caccgaaatgacctggtgagcggccgcctccccgtgggcctcagtctcaaggagcaaggt gaatgtctcagcctggcggtgctggacttggcccggatggcccgcgagcaggctcagcag ccggaggagctgctgaagactgtcagctacaaggtctgcctgccccccgacctgcgcgac ctgatccagggcctgagcttcgtgacgcggaagcgcatccggaggacggtgcgccgagcc ctgcgccgcgtgaccgcctgccaggctgaccggcactcgctcatggccaagtacatcatg gacctggagaggctcgacccggccagggctgtcgagaccttcctcgtgagcttccccggg gctgctggtggtcaggatgcgcaggggctgctccgagtggccggtgacctcggcatcgcc tggagtcccggaggacaggaggccctccagcccttctgcgactttccagaaattgtggac atcagcatcaagcaggctccgcgtgctggcccggctggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcctgccgcattgtcc ttcgtagcgctcgtcgacggatacttccggctgacctcggactccaggcacttcttctgc aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggccccatc acgctggattttgccatcaacaagctcaagactggaggctcacttcctggctcttacgtt ctccgccgcagtccccaagattttgacagcttccttctcactgtctgtgtccagaccccc ttgggtcctgattacaagggctgcctaatccggtgtgaccccacgggaaccttctccctg gctgggcttggccgtccccacagcagccttcgagaactcttgacagcttgctgggatggc gggctgcacatggacggagctgcactgaacctcaccttctgctgcacccccagacccaaa gaaaagtccaacctgattgtggtgcggaggggttgcagcctacccacatcatcccctgtt cagccgcaatcccaatgccagctcagtcagatgacatttcacaagatccctgctgacagc ctggagtggcatgagaacctgggtcatgggtccttcaccaagatctaccggggttgtcgc catgaggtcgtggatggggaggcccgggagacagaggtgttgctcaaagtgatggatgcc aagcacaaaaactgcatggagtcatttctggaagcagcgagtttgatgagccaagtgtca taccagcatctcgtgttgctccatggcgtgtgcatggctggagacagtatcatggtgcag gaatttgtacacctgggagcgctggacacatacctgcgcaagtctggccacctggtgcca gccagctggaagctacaggtgataaaacagctggcatatgccctcaactacctggaagac aaaggcctcccccatggcaatgtctcagcccggaaggtactcctggctcgggagggggcc gatgggaacctgcccttcatcaagctgagtgatcctggtgtcagccccactgtgctaagc ctggagatgctcactgacaggatcccctgggtggcccctgagtgtcttcaggaggcccga acacttggcttggaagctgacaagtggggttttggtgccacagtctgggaagtgttcagc gggatcccgatgcccatcagcaccctggatccagccaagaagctccagttttatgaggaa cggcagcagctacctgctccgaagtggatggagctggctgtcctgatccaacagtgcatg gtctatgagccaggccagaggccctccttccgtgccatcatccgtgacctgaacagcctc atcacttcagattatgagcttctctcagatcccacacctggtgccttggcaccccgcgat gggctgtggaacggtgcccagctctatgcataccaggaccctaccatttttgaggagaga cacctcaagtacatctcacagctgggcaagggtaactttgggagtgtggaactgtgccgc tatgacccactgggtgacaacacgggcgccctagtggctgtgaagcagctgcagcacagc gggccagaccagcagagggacttccagagagagatccagatcctcaaagccctccacagt gacttcattgtcaagtaccgtggagtcagctatggcccaggccgccagagcctgcggctg gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggcaccgcgcgcgc ctcgacgccggccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcagcccgcaacatcctggtggagagcgag acgcacgtcaagatcgccgactttggcctcgccaagctgctgcccctcgacaaagactac tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctct gacaacatcttctcgcgccagtcggacgtctggagcttcggggttgtcctgtacgagctt ttcacctatggcaacaagagttgcagcccctcagccgagttcctgaggatgatgggatgt gagcgagatgtcccggccctctgccgcctgctggagctgctggctgagggccagaggctg cccgcgcctcctgcctgccctggtgaggttcacgagctcatgaagctgtgctgggccccc agcccgaacgaccggccaacattcagtgccctgggcccccagctggatgcactctggagt ggaggccggggggtagcatag

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