Vulpes lagopus (Arctic fox): 121500453 Help Entry 121500453         CDS       T07435                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg01523   Antifolate resistance vlg04010   MAPK signaling pathway vlg04060   Cytokine-cytokine receptor interaction vlg04061   Viral protein interaction with cytokine and cytokine receptor vlg04064   NF-kappa B signaling pathway vlg04071   Sphingolipid signaling pathway vlg04150   mTOR signaling pathway vlg04210   Apoptosis vlg04217   Necroptosis vlg04350   TGF-beta signaling pathway vlg04380   Osteoclast differentiation vlg04612   Antigen processing and presentation vlg04620   Toll-like receptor signaling pathway vlg04621   NOD-like receptor signaling pathway vlg04622   RIG-I-like receptor signaling pathway vlg04625   C-type lectin receptor signaling pathway vlg04640   Hematopoietic cell lineage vlg04650   Natural killer cell mediated cytotoxicity vlg04657   IL-17 signaling pathway vlg04660   T cell receptor signaling pathway vlg04664   Fc epsilon RI signaling pathway vlg04668   TNF signaling pathway vlg04920   Adipocytokine signaling pathway vlg04930   Type II diabetes mellitus vlg04931   Insulin resistance vlg04932   Non-alcoholic fatty liver disease vlg04933   AGE-RAGE signaling pathway in diabetic complications vlg04936   Alcoholic liver disease vlg04940   Type I diabetes mellitus vlg05010   Alzheimer disease vlg05014   Amyotrophic lateral sclerosis vlg05020   Prion disease vlg05022   Pathways of neurodegeneration - multiple diseases vlg05132   Salmonella infection vlg05133   Pertussis vlg05134   Legionellosis vlg05135   Yersinia infection vlg05140   Leishmaniasis vlg05142   Chagas disease vlg05143   African trypanosomiasis vlg05144   Malaria vlg05145   Toxoplasmosis vlg05146   Amoebiasis vlg05152   Tuberculosis vlg05160   Hepatitis C vlg05161   Hepatitis B vlg05163   Human cytomegalovirus infection vlg05164   Influenza A vlg05165   Human papillomavirus infection vlg05166   Human T-cell leukemia virus 1 infection vlg05168   Herpes simplex virus 1 infection vlg05169   Epstein-Barr virus infection vlg05170   Human immunodeficiency virus 1 infection vlg05171   Coronavirus disease - COVID-19 vlg05205   Proteoglycans in cancer vlg05310   Asthma vlg05321   Inflammatory bowel disease vlg05322   Systemic lupus erythematosus vlg05323   Rheumatoid arthritis vlg05330   Allograft rejection vlg05332   Graft-versus-host disease vlg05410   Hypertrophic cardiomyopathy vlg05414   Dilated cardiomyopathy vlg05417   Lipid and atherosclerosis vlg05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:vlg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     121500453 (TNF)    04350 TGF-beta signaling pathway     121500453 (TNF)    04064 NF-kappa B signaling pathway     121500453 (TNF)    04668 TNF signaling pathway     121500453 (TNF)    04071 Sphingolipid signaling pathway     121500453 (TNF)    04150 mTOR signaling pathway     121500453 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     121500453 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     121500453 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     121500453 (TNF)    04217 Necroptosis     121500453 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     121500453 (TNF)    04620 Toll-like receptor signaling pathway     121500453 (TNF)    04621 NOD-like receptor signaling pathway     121500453 (TNF)    04622 RIG-I-like receptor signaling pathway     121500453 (TNF)    04625 C-type lectin receptor signaling pathway     121500453 (TNF)    04650 Natural killer cell mediated cytotoxicity     121500453 (TNF)    04612 Antigen processing and presentation     121500453 (TNF)    04660 T cell receptor signaling pathway     121500453 (TNF)    04657 IL-17 signaling pathway     121500453 (TNF)    04664 Fc epsilon RI signaling pathway     121500453 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     121500453 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     121500453 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     121500453 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121500453 (TNF)    05170 Human immunodeficiency virus 1 infection     121500453 (TNF)    05161 Hepatitis B     121500453 (TNF)    05160 Hepatitis C     121500453 (TNF)    05171 Coronavirus disease - COVID-19     121500453 (TNF)    05164 Influenza A     121500453 (TNF)    05168 Herpes simplex virus 1 infection     121500453 (TNF)    05163 Human cytomegalovirus infection     121500453 (TNF)    05169 Epstein-Barr virus infection     121500453 (TNF)    05165 Human papillomavirus infection     121500453 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     121500453 (TNF)    05135 Yersinia infection     121500453 (TNF)    05133 Pertussis     121500453 (TNF)    05134 Legionellosis     121500453 (TNF)    05152 Tuberculosis     121500453 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     121500453 (TNF)    05144 Malaria     121500453 (TNF)    05145 Toxoplasmosis     121500453 (TNF)    05140 Leishmaniasis     121500453 (TNF)    05142 Chagas disease     121500453 (TNF)    05143 African trypanosomiasis     121500453 (TNF)   09163 Immune disease    05310 Asthma     121500453 (TNF)    05322 Systemic lupus erythematosus     121500453 (TNF)    05323 Rheumatoid arthritis     121500453 (TNF)    05321 Inflammatory bowel disease     121500453 (TNF)    05330 Allograft rejection     121500453 (TNF)    05332 Graft-versus-host disease     121500453 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     121500453 (TNF)    05014 Amyotrophic lateral sclerosis     121500453 (TNF)    05020 Prion disease     121500453 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     121500453 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     121500453 (TNF)    05418 Fluid shear stress and atherosclerosis     121500453 (TNF)    05410 Hypertrophic cardiomyopathy     121500453 (TNF)    05414 Dilated cardiomyopathy     121500453 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     121500453 (TNF)    04940 Type I diabetes mellitus     121500453 (TNF)    04936 Alcoholic liver disease     121500453 (TNF)    04932 Non-alcoholic fatty liver disease     121500453 (TNF)    04931 Insulin resistance     121500453 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     121500453 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     121500453 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:vlg04052]     121500453 (TNF)    00536 Glycosaminoglycan binding proteins [BR:vlg00536]     121500453 (TNF) Cytokines and neuropeptides [BR:vlg04052]  Cytokines   Tumor necrosis fators    121500453 (TNF) Glycosaminoglycan binding proteins [BR:vlg00536]  Heparan sulfate / Heparin   Cytokines    121500453 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  121500453 NCBI-ProteinID:  XP_041628106 LinkDB All DBs Position 1:complement(72016353..72019086) Genome browser AA seq 233 aa AA seqDB search MSTESMIRDVELAEEPLPKKAGGPPGSRRCFCLSLFSFLLVAGATTLFCLLHFGVIGPQR EELPNGLQLISPLAQTVKSSSRTPSDKPVAHVVANPEAEGQLQWLSRRANALLANGVELK DNQLIVPSDGLYLIYSQVLFKGQGCPSTHVLLTHTISRFAVSYQTKVNLLSAIKSPCQRE TPEGTEAKPWYEPIYLGGVFQLEKGDRLSAEINLPNYLDFAESGQVYFGIIAL NT seq 702 nt NT seq  +upstreamnt  +downstreamnt atgagcactgaaagcatgatccgggacgtggagctggccgaggagccgctccccaagaag gcagggggccccccgggctccagaaggtgcttctgcctcagcctcttctccttcctcctc gtcgcaggagccaccacactcttctgcctgctgcactttggagtgatcggcccccagagg gaagagctcccaaatggcctccaactaatcagccctcttgcccagacagtcaaatcatct tctcgaaccccaagtgacaagccagtagctcatgttgtagcaaaccccgaagctgagggg cagctccagtggctgagccgacgtgccaatgccctcctggccaacggcgtggagctgaaa gacaaccagctgatagtgccgtcagatgggttgtacctcatctactcccaggtcctcttc aagggccaaggatgcccttccacccatgtgctcctcacccacaccatcagccgctttgcc gtctcctaccagacaaaggtcaacctactctctgccatcaagagcccttgccaaagggag accccagaggggaccgaggccaagccttggtacgagcccatctacctgggaggggtcttc caactggagaagggtgatcgactcagtgctgagatcaatctgcctaactatctggacttt gccgagtccgggcaggtgtactttggaatcattgccctgtaa

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