Vicugna pacos (alpaca): 102526528 Help Entry 102526528         CDS       T08098                                  Symbol ESPL1 Name (RefSeq) separin   KO K02365   separase [EC:3.4.22.49] Organism vpc  Vicugna pacos (alpaca) Pathway vpc04110   Cell cycle vpc04114   Oocyte meiosis vpc05166   Human T-cell leukemia virus 1 infection Brite KEGG Orthology (KO) [BR:vpc00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     102526528 (ESPL1)    04114 Oocyte meiosis     102526528 (ESPL1)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102526528 (ESPL1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:vpc01002]     102526528 (ESPL1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:vpc03036]     102526528 (ESPL1) Enzymes [BR:vpc01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.49  separase      102526528 (ESPL1) Peptidases and inhibitors [BR:vpc01002]  Cysteine peptidases   Family C50: separase family    102526528 (ESPL1) Chromosome and associated proteins [BR:vpc03036]  Eukaryotic type   Sister chromatid separation proteins    Separase     102526528 (ESPL1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C50 CHAT Motif Other DBs NCBI-GeneID:  102526528 NCBI-ProteinID:  XP_031538710 UniProt:  A0A6J3AVS9 LinkDB All DBs Position 12 AA seq 1968 aa AA seqDB search MRSFKGVNFGTLLSSPKEAEELLPDLKEFLSKLPAGSPCCRSDVEKRQACDAILRACNQQ LTVRLACPRHLGSLLELAELACDGYLMSTPQRPPLYLERILFIFLRNIAAQGIPEATLRL AQPLHACLVQCSRHAAPQDYEAVARGSFSLLWKAAEALVERRAAFSARLKALSFLVLLED ESTPCEVPHFSSPTACRVVAAHQLFDASGHGLNESDADFLDDLLSRQVIRALVGEGGGSP GPLSPQRALCLLELTLEHCRRLCWSHHHAKATSVVEKAHDYLRNTNLAPSLQLCHLAIKL LQVGEGGPQAVAKLLIQASTVLKNSMEASLPPLRALCDSCQFFLSVLERGTKGRCGPDAI LGLFAFLGDYCSLIRHLQDGVCGDSSKQQQALVQMYFQGLHLYTVVVYDFAQGCQVADLA PLAQLVESCKSTVVWMLEVLQGLSGRELTDSLGMTASYTSNLAYSFYSHKLYAEACAISE PLCQHLGLAKPSTYPEVPPDKLHRCFRLHVESLKKLGKQAQGCKMVTLWLAALQPCGPEH MTEPVTFWVRVKMDAARAGDKELQLKTLRDSLSGWDPETLAVLLREELQAYKAVRADTGQ ERFNVICDLLELSPEETPAGAWARATHLVELAQVLCYHDFAQQTDCSALDAIQEALQLLE SVRPEAEAKDRLLDDKAQALLWLYICTLEAKMREGIERDRRAQAPSNLEEFEVNDLNYED KLQEDRFLYSNIAFNLAADAAQSKCLDQALALWKEVLTKGQAPSVRCLQQTAASLQILAA LYQLVAKPLQALEVLLLVQIVSQRLEDHAKAAGSSCHVTQLLLTLGCPSYAQLYLKKAES SLKLLDHTTDTYLLLSLTCDLLRSQLYCDCQKVTEGASLLLSVLRDPALQRSSKAWYLLR VQALQLVAVYLSLSSDSLSASLWEQLCAQGWQTPEIALIDSHKLLRSIILLLMGSDMLST QKTAVETPFLDYGENLVQKWQVLTEVLSCSEKLVSRLGRLGSVSEAKAFCLEALKLTTKL QIPRQCALFLALKGELELARSDVDLCQSDLQQVLFLLESCTEFVGLAQHPGSVKKIHLRK GQQQARAPRPPQLPEEELVLRGPALELVATVAKEPGPMAPSTNSSPILKTKPQPSPGFLT HLPTCDCSLCASPVLSAVCLRWALVTAGVRLAMGHRAQGVDLLQVVLKGCPAATKRLTQA LQASLNHKAAPSPVPGLFDEILAQAYTQLALEELSQPSNKSLGKVLESGLKASVMVNFSD DSDLEDPVSVEAWLAEGPKRRGTASRGRGRARKGPSVKTSAVAAPGSAPGHPGLSGRSLR AKKVASGHCEELGPEMMRTIPEEELNDNQMERSFEILRGSDGEDSASGGKTPVPGPDTAM GECEVLRRDVSKEELPVPCPDKDLGPQLQTPSAFGAVSLSTLDSICDSLSVALRGVSHCP PSGLYAHLCRVLALCLGHRDPCATACLVTESVSITCRHQLLIHLHRQLSKAQKRQGSLKI ADQLQGLSLQERPGDVPLARIQRLFSFRTLGSGHFPQPEKESFQERLALIPSGMTVCVLA LATLQPGTVGDTLLLTRLEKDNPPVTVQIPTAQNQLSLSSALKEFDAIQKEQKENSSCTD KREWWTGRLELDRRMEVLTTSLEKYVLGCWRGLLLPSSEDPGPAQEASCLQELLRECGWK YPDPTLLKVLLSSASTLTPQDIQALAYGLCPAWPERAQELLSEAVGRLQGQMGPSSKHLV LVLDKDLQKLPWESMPSLRALPVTRLPSFRFLLSYSIIKQSGASSVLSQGVDPRSTFYVL NPHNNLSNTEEQFRAHFSSEAGWKGVVGEVPSPEQVQAALTEHDLYIYAGHGAGARFLDG QAVLRLSCRAVALLFGCSSAALAVHGNLEGAGIVLKYIMAGCPLFLGNLWDVTDRDIDRY TEALLQSWLGAGPGAPLLYYVNQARQAPRLKYLIGAAPVAYGLPVSLR NT seq 5907 nt NT seq  +upstreamnt  +downstreamnt atgaggagcttcaaaggagtcaactttggaactctgctaagcagtccaaaggaggctgaa gagttgctgcctgacttgaaggagttcctgtccaagcttccagctggttctccctgctgc cggtctgatgtggagaagagacaagcttgtgatgccatactaagggcttgcaaccagcag ttgactgtcaggctggcttgccctagacacctggggagcctgctggagctggcagagctg gcttgcgatggctacttgatgtctaccccccagcgcccacccctctacctggaaagaatt ctcttcatctttctgcgaaacattgctgcacagggaatcccagaggctacactccgactt gctcagcccctccatgcctgcttggtgcagtgctctcgccatgctgctccccaggactac gaggctgtggctcggggtagcttttctctgctttggaaggcagcagaagccctggtggag cggcgagctgcattctcagctcggctgaaggccttgagttttctagtactcttggaggat gaaagtaccccttgtgaggttccccacttctcttctccaacagcctgtcgagtggtagct gcccatcagctatttgatgccagtgggcatggtctgaatgagtcagatgctgatttccta gatgacctgctctccaggcaggtgatcagagccttggtgggtgagggagggggctctcct ggtcctctttcccctcagagggccctctgcctcttggagcttaccctggaacattgccgt cgcctctgctggagccaccaccatgccaaggccaccagcgtagtggagaaggcccacgat tacctaaggaacaccaatctggcccccagcctccagctatgccacctggccatcaaactg ctgcaggttggggagggaggaccccaggcagtggccaagcttctgatccaggcgtcaact gtcctgaagaacagtatggaggcatcgttgcccccactgcgagcattgtgtgacagctgc cagttcttcctctcagtcctggagcgagggaccaaggggcgctgtggacctgatgctatc ctgggcctctttgcttttcttggcgactactgttcccttatccggcatctgcaggatggc gtctgtggggactcctccaagcagcagcaggctttggttcagatgtactttcagggactt catctctacactgtggtggtttatgactttgcccaaggctgtcaggtagctgacttggct cccctggcccagctagtggaaagttgcaaatctactgttgtctggatgctggaggtctta cagggcctgtcaggccgagagctgactgactccctggggatgaccgcctcctacaccagt aacttggcctacagcttctatagtcacaagctctacgccgaggcctgtgccatctctgag cccctctgtcagcacttaggcttggcgaagcccagcacctatcctgaggtgcctcctgac aagttgcacaggtgcttccggctgcatgtagagagtttgaagaaactgggtaaacaggcc cagggctgcaagatggtgactttgtggctggcagccctgcagccctgcggccccgaacac atgactgagccagtcaccttctgggtccgggtcaagatggatgcagccagagccggagac aaggagctccagctgaagacgctgcgagacagcctgagtggctgggacccggagaccctg gccgtcctgctcagggaggagctgcaggcctacaaggcagtgcgggctgacacggggcag gaacggttcaacgtcatctgtgacctgctggagctgagccctgaggagacaccggctggg gcctgggctcgagccacccacctggtggaactggcccaggtgctctgctaccacgacttt gcccagcagactgactgctctgccctggatgccatccaggaagctctgcagcttctggag tctgtgaggcccgaagccgaggccaaggatcggcttctggatgataaagcacaggccctg ctgtggctctacatctgcaccctggaggccaaaatgcgggagggtattgagcgggatcgg agagcccaggcccctagtaacctggaggagtttgaagtcaatgacctgaactatgaagac aaactccaggaagatcgtttcctatacagtaacattgccttcaacctggctgcagatgct gctcagtccaaatgcctggaccaagccctggccctgtggaaggaggtgcttacaaagggg caggccccctctgtgcggtgtctccagcagacagcagcctccctgcagatcctggcggcc ctctatcagctggtggccaagcccctgcaggctctggaggtcctcctgcttgtgcagatc gtctctcagagactggaggaccacgccaaggcagctggctcctcctgccacgtcacccag ctgctcctgacactcggctgtcccagctatgctcagctgtacctgaaaaaggcagaatca agtctgaagcttctggatcacaccactgacacgtatttgctcctttccctgacctgtgac ctactgcgaagtcaactctactgcgattgccagaaggtgactgagggcgcctctctgctg ctgtctgtgcttcgggaccctgccctccagaggtcatccaaggcctggtacttgctccgc gtgcaggccctgcagctggtggccgtctaccttagcctctcatcagatagcctctcagcc tcgctgtgggagcagctctgtgcccaaggctggcagacacctgagatagcgctcatcgac tcccataagctcctccgaagcatcatcctcctgctcatgggcagcgacatgctctcgact cagaaaacagctgtggagacaccgtttctggactatggtgaaaatctggtacagaaatgg caggttcttactgaggtgctaagctgctcagagaagctggtctcgcgcctgggccgcctg ggtagtgtgagtgaagccaaggccttttgcttagaggccctgaaactcacaacgaagctg cagataccacgccagtgtgccttgttcctggcgctgaagggggagctggagctggcgcgc agtgacgtcgacctctgtcagtcggacctgcagcaggttctgttcttgctggagtcctgc acagagtttgtcggactagcgcagcacccaggctctgtgaagaagatccacttgcggaag gggcagcagcaggcccgggcgccccgccctccacagctcccagaggaagagctcgtcctg agaggccctgccctggaactggtggccactgtggccaaagagcctggccccatggcacct tctacaaactcttccccaatcctgaaaacgaagccccagcccagccctggcttcctgacc catttgcccacctgtgactgctcactctgtgccagccctgtcctctcggcagtctgtctg cgctgggcgttggtcacagcaggggtgaggctggccatgggccatcgggcccagggtgtg gatctgctgcaagttgtgctaaagggttgccctgcagccactaagcgcctcacacaagct ctgcaagcttccctgaatcacaaagcagccccttcccctgtcccaggcctctttgatgag atcttggctcaggcatacacacagctggcactggaggagctgagccagccatcaaacaag agcctagggaaggtcctggagtcggggctgaaggcctctgtgatggtgaacttcagtgat gacagtgacttggaagaccctgtctcagttgaggcatggcttgcggagggacccaagaga cgaggcactgcttcccgcggccggggccgagctaggaagggcccgagcgtgaagactagt gcagtggctgccccaggtagtgcccctgggcaccctggccttagtggcagaagcctgagg gccaagaaggtggcatcgggacattgtgaggaactgggccccgagatgatgaggaccatc cctgaggaggaactgaatgacaaccagatggaaaggagctttgagatcctcaggggctct gatggggaagactctgcctcaggtgggaagacaccagttccagggcctgatacagccatg ggggaatgtgaggtgctgagacgggatgtcagcaaagaggagctgcccgtcccttgccca gacaaggatctcggtcctcagctccaaaccccctcagccttcggggctgtcagtctgtcc accctggattccatctgtgactcactgagcgttgctttgcgtggggtcagtcactgccct cctagtgggctctatgctcacctgtgccgcgtcctggctttgtgcctgggccaccgggat ccctgtgccactgcctgccttgtcaccgaatctgtctccatcacctgtcgccaccagctg ctcatccacctccacaggcagctcagcaaggcccagaagcgccaaggatcactcaaaata gcagaccagctgcaggggctgagcctgcaggagaggcctggagacgtccccctggcccgc attcagcgcctcttttccttcaggactttgggatctggtcacttcccccagccagagaag gagagtttccaggagcgcctggctctgatccccagtgggatgactgtgtgtgtgttggcc ctggccacccttcagcctggaactgtaggcgacaccctcctgctgactcgactggaaaaa gacaatcccccagtcactgtgcagatccccactgcccagaaccagctatctctgagttcg gctctgaaagagtttgacgccatccaaaaggaacagaaagagaacagcagctgtactgac aaacgagaatggtggacgggacggctggagctggaccgtaggatggaggttctcaccact tccctagagaagtacgtgctgggctgctggagggggctgctgctgccgtccagtgaggac cctggccctgcccaggaggcctcctgtctacaggagttgctgcgggaatgtggctggaaa tatcctgaccccactctgctgaaagtcctgctcagcagtgccagtaccctcaccccgcag gacattcaggccctggcctatgggctgtgcccagcctggccagaacgagcccaagagctc ctgagtgaggcagtaggacgtctacagggtcagatgggaccaagcagtaagcatcttgtc ttagtgctggacaaggacctgcagaagctgccgtgggaaagcatgcccagcctccgggcc ctgcctgtcaccaggctgccctctttccgattcctcctcagctactccatcatcaaacag tccggggcatcgtcggtgctgagccaaggggtggatcctcgcagtaccttctacgtcctg aaccctcacaataatctgtccaacacagaggagcaattccgagcccattttagcagtgaa gctggctggaaaggggtggtcggggaggtgccgagcccagaacaggtgcaagcggccctg acagagcatgacttatacatttatgcagggcacggggccggcgcccgcttcctcgatggg caggctgtcctgcggctgagctgccgggcagtggccctgctgtttggctgcagcagtgcg gccctggctgtgcacggaaacctagagggggctggcatcgtgctcaagtatatcatggct ggctgccccctgtttctaggtaacctctgggatgtgactgaccgtgacattgaccgctat acggaggctctactgcagagctggcttggagcaggcccaggagccccgctcctgtactat gtcaaccaggcccgccaggctccccgactcaagtatcttattggggcagcaccagtagcc tatggcttgcctgtgtccctgcggtga

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