Vicugna pacos (alpaca): 102527039
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Entry
102527039 CDS
T08098
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04120
Ubiquitin mediated proteolysis
vpc04144
Endocytosis
vpc04330
Notch signaling pathway
vpc04668
TNF signaling pathway
vpc04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102527039 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102527039 (ITCH)
04668 TNF signaling pathway
102527039 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102527039 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102527039 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vpc04131
]
102527039 (ITCH)
04121 Ubiquitin system [BR:
vpc04121
]
102527039 (ITCH)
Enzymes [BR:
vpc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102527039 (ITCH)
Membrane trafficking [BR:
vpc04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102527039 (ITCH)
Ubiquitin system [BR:
vpc04121
]
Ubiquitin ligases (E3)
HECT type E3
102527039 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102527039
NCBI-ProteinID:
XP_031543841
LinkDB
All DBs
Position
19
AA seq
915 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKFEEVVVTL
QLVGDKEPTETIGDLSICLDGLQLDSEVVTNGETTCSQSASQNDDGSRPKDETRMNTNGS
DEPEDAGSGENRRVNGNNSPSLSNGSFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQATLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWGKSHEFLKLNSVILMIR
CLWVDGTLCSCLSEILGSFLGLQNTGLNGFLEVSTAFMAIFTFCTWQTSKSSTFTCYVFS
YVLYSQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDF
KAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSAQDLRRRLWVIFSGEEGLD
YGGIAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMA
LFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVD
KEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQ
YLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQILWFWQFVKEIDNEKRMRLL
QFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKE
KLLFAIEETEGFGQE
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagattactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccgtatgtggaagtcactgtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctcttacagttattgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaatttgaggaagtagttgtgacttta
cagctggtaggtgacaaagaaccaacagagacaataggagatttgtcgatttgtcttgat
ggactgcagttagattcagaagttgttactaacggtgaaactacgtgttcacaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaatgaacacaaatggatct
gacgaacctgaggatgcagggtctggtgaaaataggagagtcaatgggaacaattctcca
tcactctcaaatggcagttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctaccacttctgaaagtgat
ggctctagtacgggctctctgccaccaacgaatacaaattcaaatacatctgaaggagca
acatccggattaataattcctcttactatatctggaggctcaggccctagaccattaaat
cctgtacctcaagctaccctcccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacatgggatagaccagaacctctacct
cctggttgggaacggcgggttgacaacatgggacgtatttattacgttgaccatttcaca
agaacaacgacgtggcagaggccaacattggaatctgtccggaactatgaacaatggcag
ctccaacgaagtcagcttcaaggagctatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctcggtcccctgcca
cctggatggggtaagtcacatgaatttttaaaattgaattcagttattttaatgatcagg
tgtttatgggtagatggtacactctgctcttgcttgagtgaaattctaggaagctttttg
ggtttacaaaatactggactaaatggttttctggaagtttctactgcatttatggctatt
tttactttttgtacttggcaaacaagcaagtcttcaacatttacttgttatgtattttcc
tatgttttatatagtcaattaaatgaaaagcccttacctgaaggctgggaaatgagattt
acagtggatggaattccatattttgtggaccacaatagaagaacaaccacttatatagat
ccccgcactggaaaatctgccttagacaatggaccccagatagcctatgtacgggacttc
aaggcaaaggttcagtatttccggttctggtgtcagcaactggccatgccacagcatata
aagattaccgtgacaagaaaaacattgtttgaggattcttttcagcagataatgagcttc
agtgcccaagatctgcgaagacgtttgtgggtgattttttcaggagaagaaggtttagat
tatggaggtatagcaagagaatggttctttcttttgtcacatgaggtgttgaacccaatg
tattgcctgtttgaatatgcagggaaggataactactgcctgcagataaatcctgcttct
tacatcaatccggatcacctgaaatattttcgttttattggcaggtttattgctatggct
ctgttccatgggaaattcatagacacaggtttttctttgccattctataagcgtatcttg
aacaaaccagttgggctcaaggatttagaatctattgatccagaattttacaattctctc
atctgggtaaaagaaaacaatattgaggagtgtggtttggaaatgtatttttccgtcgat
aaagaaattttgggtgaaatcaagagtcatgatttgaaacccaatggcggcaatattctt
gtaacagaagaaaataaagaggaatatatcagaatggtagctgaatggaggttgtctcgt
ggtgttgaagaacagacacaagctttctttgagggctttaacgaaattcttccccagcag
tatttgcaatattttgatgcaaaggaattagaggtccttctgtgtggaatgcaagagatt
gatttgaatgactggcaaagacatgccatctaccgtcattacactaggacaagcaaacaa
atcttgtggttttggcagtttgttaaagaaatcgataatgagaagagaatgagacttttg
cagtttgttactggaacctgccgattaccagtcggaggatttgctgacctcatggggagc
aatggaccacagaaattctgcattgaaaaagttgggaaagaaaactggttacccagaagt
catacctgttttaaccgcctggatctgccaccctataagagctatgagcaactgaaggaa
aagctgttatttgccattgaagaaacagaaggatttggacaagagtga
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