Vicugna pacos (alpaca): 102527204
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Entry
102527204 CDS
T08098
Symbol
EIF2AK3
Name
(RefSeq) LOW QUALITY PROTEIN: eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04137
Mitophagy - animal
vpc04140
Autophagy - animal
vpc04141
Protein processing in endoplasmic reticulum
vpc04210
Apoptosis
vpc04932
Non-alcoholic fatty liver disease
vpc05010
Alzheimer disease
vpc05012
Parkinson disease
vpc05014
Amyotrophic lateral sclerosis
vpc05020
Prion disease
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05160
Hepatitis C
vpc05162
Measles
vpc05168
Herpes simplex virus 1 infection
vpc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102527204 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102527204 (EIF2AK3)
04137 Mitophagy - animal
102527204 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
102527204 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
102527204 (EIF2AK3)
05162 Measles
102527204 (EIF2AK3)
05168 Herpes simplex virus 1 infection
102527204 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
102527204 (EIF2AK3)
05012 Parkinson disease
102527204 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
102527204 (EIF2AK3)
05020 Prion disease
102527204 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
102527204 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102527204 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102527204 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102527204 (EIF2AK3)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102527204 (EIF2AK3)
Protein kinases [BR:
vpc01001
]
Serine/threonine kinases: Other
PEK family [OT]
102527204 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
APH
Motif
Other DBs
NCBI-GeneID:
102527204
NCBI-ProteinID:
XP_006203880
UniProt:
A0A6I9I502
LinkDB
All DBs
Position
28
AA seq
1115 aa
AA seq
DB search
MERATRPGSLARALLLPLLLGIAAGTVDARLASDIPAPTAEAAFGXGAAAAPTAAARVPA
AGAVTAAEVTVEDAEALPAAAGEQEEREPEPEDEAELRPCGRSLVIISTLDGRIAALDPE
NHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESL
LESSYKFGDDVVLVGGKSLTTYGLGAYSGKVRYICSALGCRQWDSDEVEPEEGILLLQRT
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPHGNKEQSKIISDVDEQ
EAVMMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVVPISLFDDTSY
APNDGVLEDEEDIVEAARGATESSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNGEN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERSKRSTQITVRFLDNPNYSKNVRRKDPVLLLHWWKEIVGTILFCIVATTFIVR
RLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWSDIKNSGYVSRYLTDFEPVQCMGR
GGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPVDAPSVKVRRMDPFSTKERIEIIAPSPRSGRS
FSVGISCGRTSSSESQFSPLEFSGMDHRDMSESVDAVNNLPDSCLTDCDVEDGTMDGNDE
GHSFELCPSEASPNIRSRERTSSSIVFEDSGCDNASSKEEPRTNRPPLGNHYANKLTAVQ
HSNSRPSSEPTFSISPPRPTTLSLDLTTNPAEKPQPSSPKVYLYIQMQLCRKENLKDWLN
SRCTIEERERSACLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTA
MDQDEEDQMVLTPMPGYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPF
ATQMERVRILTDVRDLKFPPLFTQKYPREYAMVQDMLSPCPTERPEAANIIENAIFEDLE
FPGKTVLRQRSRSLSSSGTKHSRHSSSSHSPLPSN
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccactcgcccggggtcgctcgcgcgggcgctgctactgccgctgctgctg
gggatcgcggctgggaccgtggatgcgcggctcgcctccgacatccccgcacccaccgcg
gaggcggcgttcggcntgggggcggcggctgctcccactgcggccgcgcgggtgcccgcg
gcgggcgctgtgactgcagctgaggtgactgtggaggatgcagaggcgctgccggcagcc
gcgggcgagcaggaggagcgggagcccgaacccgaggacgaggccgagcttcggccgtgc
ggcagatcattagtgattatcagcactttagatggccgaatcgctgccttggatcctgag
aatcatggtaaaaagcagtgggatttggacgtgggatccggttccttggtgtcatccagc
cttagcaaaccagaggtatttgggaacaagatgatcatcccttccctggatggagacctc
ttccagtgggaccgagaccgcgagagcatggaaacagttccgtttacagttgaatcactt
cttgaatcgtcttataagtttggagatgatgtcgtcttggttggaggaaagtccctcact
acgtatggacttggtgcatatagtgggaaggtgaggtacatctgttcagctctgggctgt
cgccagtgggacagtgatgaagtggaaccagaagagggcatcctgcttctgcagcgcacc
cagaaaaccgtgagagcggtcggacctcgcagtggcaatgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagc
actttaaaaccccatggaaacaaagaacagtctaaaattatttcagatgtggatgaacag
gaagctgtcatgatggacacagtgataaaggtctccgtagccgactggaaagttatggcg
tttagtaagaagggaggacatctcgaatgggaataccagttttgtacgcccattgcctct
gcctggttggtgaaggatggcaaagtcgttcccatcagtctttttgatgatacgagttac
gcccctaatgatggagttttagaagatgaagaagacattgtagaggctgcgcgaggagcc
acggagagcagcgtctacctgggaatgtacagaggccagctgtatctgcagtcatcagtc
agaatttcagaaaaatttcctacgagtcccaaggccttggaatctgtcaatggtgaaaat
gccattattcctttgccaacaatcaaatggaaacccttaattcattctccttccagaact
cctgtcttggtagggtctgatgaattcgacaaatgtctaagtaacgataagttttctcat
gaagagtacagcaatggtgccctttcaatcttacagtatccgtatgataatggatattac
ctgccctactacaagagggaaaggagcaaacggagcacgcagatcacggtcaggtttctg
gacaatccgaattacagcaagaatgtccgcaggaaggaccctgtcctcctcttacactgg
tggaaggaaatcgttggaactatcctgttttgtatcgtagcaacaactttcattgtgcgc
cgacttttccatcctcaccctcacagacaaaggaaggagtctgaaactcagtgtcaaact
gaaaataaatatgattctgtaagtggagaagctaatgacagtagctggagtgacataaaa
aattctggatatgtatcacgatatctaacagattttgaaccggttcagtgcatgggtcgc
ggggggtttggagttgtcttcgaagctagaaacaaagtagatgactgcaattatgctatc
aagagaatccgtctccccaacagggaactggctcgggagaaggtaatgcgagaagtgaaa
gctttggccaagcttgagcacccaggaattgtcaggtatttcaatgcttggttggaagca
ccaccagagaagtggcaagaaaaaatggatgaaatctggctgaaagatgaaagcacagac
tggccgctcagctctcccagtccggtggatgccccctccgttaaagtacgcagaatggat
cctttctctacgaaggaacgtatcgaaatcatagctccttcgccacgaagtggcagatct
ttttcagtagggatctcctgtggccggacaagttcgtctgagagccagttctctccactg
gaattttccggaatggaccacagagacatgagtgagtcggtggatgctgtgaacaacctc
ccggacagttgccttacggactgcgatgtggaagatggtactatggatggcaatgatgag
gggcactcctttgaactttgtccctctgaagcttctcctaatataaggtcaagggagcga
acatcctcttccatagtatttgaagactccggctgtgataacgcgtccagcaaagaagag
cccagaacgaaccgaccgcctctgggcaaccattatgctaataaactaactgctgtccag
cattccaacagcaggccttcttcagaacccaccttttctatttctcctccgaggccaacc
actttaagtttagatctcactacaaaccctgcggaaaaaccgcagcccagttcaccgaag
gtgtatctttacatccagatgcagctgtgcagaaaggaaaacctcaaagactggctgaac
agccgctgcaccatagaggagagagagaggagtgcgtgtctgcacatcttcctgcagatc
gccgaggcggtggagtttctgcacagcaaagggctcatgcacagggacctcaagccttcc
aacatattctttacaatggacgacgtggtcaaggttggagattttggcttagtgactgcg
atggaccaggatgaggaggaccagatggttctgaccccaatgccggggtacgccagacac
accggacaagtggggaccaagctgtatatgagcccagagcagattcatggaaacaactac
tctcataaagtggacatcttttctttgggcctcattctgtttgaattgctctacccattc
gccacgcagatggagagggtcaggatcttaactgatgtcagagatctcaaatttccacca
ctgtttactcagaaatatcctcgtgagtacgcgatggtacaagacatgctctccccatgc
cccacggaacggcctgaagctgccaacatcattgaaaatgctatatttgaggacttggag
tttccaggaaagacggtgctcagacagaggtctcgctccctgagctcatcaggaacgaaa
cattcaagacactccagcagctcccacagccctttgccaagcaattag
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