Vicugna pacos (alpaca): 102528174
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Entry
102528174 CDS
T08098
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc01524
Platinum drug resistance
vpc03320
PPAR signaling pathway
vpc04068
FoxO signaling pathway
vpc04071
Sphingolipid signaling pathway
vpc04140
Autophagy - animal
vpc04150
mTOR signaling pathway
vpc04151
PI3K-Akt signaling pathway
vpc04152
AMPK signaling pathway
vpc04210
Apoptosis
vpc04360
Axon guidance
vpc04510
Focal adhesion
vpc04660
T cell receptor signaling pathway
vpc04664
Fc epsilon RI signaling pathway
vpc04722
Neurotrophin signaling pathway
vpc04910
Insulin signaling pathway
vpc04919
Thyroid hormone signaling pathway
vpc04931
Insulin resistance
vpc04960
Aldosterone-regulated sodium reabsorption
vpc05145
Toxoplasmosis
vpc05205
Proteoglycans in cancer
vpc05208
Chemical carcinogenesis - reactive oxygen species
vpc05213
Endometrial cancer
vpc05215
Prostate cancer
vpc05223
Non-small cell lung cancer
vpc05231
Choline metabolism in cancer
vpc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
102528174 (PDPK1)
04071 Sphingolipid signaling pathway
102528174 (PDPK1)
04151 PI3K-Akt signaling pathway
102528174 (PDPK1)
04152 AMPK signaling pathway
102528174 (PDPK1)
04150 mTOR signaling pathway
102528174 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102528174 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
102528174 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102528174 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
102528174 (PDPK1)
04664 Fc epsilon RI signaling pathway
102528174 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
102528174 (PDPK1)
03320 PPAR signaling pathway
102528174 (PDPK1)
04919 Thyroid hormone signaling pathway
102528174 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
102528174 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
102528174 (PDPK1)
09158 Development and regeneration
04360 Axon guidance
102528174 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102528174 (PDPK1)
05208 Chemical carcinogenesis - reactive oxygen species
102528174 (PDPK1)
05231 Choline metabolism in cancer
102528174 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
102528174 (PDPK1)
05213 Endometrial cancer
102528174 (PDPK1)
05223 Non-small cell lung cancer
102528174 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102528174 (PDPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102528174 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102528174 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102528174 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102528174 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vpc04131
]
102528174 (PDPK1)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102528174 (PDPK1)
Protein kinases [BR:
vpc01001
]
Serine/threonine kinases: AGC group
PDK1 family
102528174 (PDPK1)
Membrane trafficking [BR:
vpc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
102528174 (PDPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
ABC1
Haspin_kinase
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
102528174
NCBI-ProteinID:
XP_031542903
UniProt:
A0A6J3BAW8
LinkDB
All DBs
Position
18
AA seq
588 aa
AA seq
DB search
MRSPLSELFSHFFKYIPPTGGAVGIGKSGNGLAQFDIKYDTVPIQSSVVLCSCPSPSMVR
TQTESSTAPGVPSGGSRQGPTMDSTAAESRPSANTLQHTTQPPPQPRKKRPEDFKFGKIL
GEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFT
FQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEMVSALEYLHGKGIIHRDLKP
ENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWAL
GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCE
EMEGYSPLKAHPFFESITWENLHHQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQV
SSSSSSHSLSAADAGLPQRAGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQASGNPW
HQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEA
KNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQEVWRHRYQSHPDAAVQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgagaagccctctgtctgagttgttttcccatttctttaagtatataccaccaacaggg
ggagcggtaggaattgggaagtctggaaatggcctggctcaatttgacattaagtatgac
accgttcctattcagtccagcgtggtgttatgttcctgcccatccccatcaatggtgagg
acccagactgagtccagcacggcccctggcgttcccagcggtggtagcaggcagggcccc
accatggacagcaccgcagctgaatcccggcccagtgccaacacgctacaacacaccaca
caaccgccaccacagcctcggaagaaacggccagaagactttaaatttgggaaaattctt
ggtgaaggctctttttcaacagttgtcctggcccgagaactggcaacctcaagggaatat
gccattaaaattctagagaaacgtcacattatcaaagagaacaaggtcccgtatgtaacc
cgagagagagacgtgatgtcacggctggatcaccccttctttgttaaactttacttcacg
tttcaggatgatgaaaagctgtattttggccttagttatgccaaaaatggagaacttctt
aaatacattcgcaaaattggttcattcgatgagacatgcacgcgattttacacagccgag
atggtgtccgccctagagtacttgcatggcaagggcatcattcacagggacctgaaacca
gagaacattttgttaaatgaagatatgcacatccagattacagattttggaacagcaaaa
gtattatccccagagagtaaacaagccagggccaactcgtttgtaggaacagcccagtat
gtttctccagagctgctcacagagaaatcggcctgtaaaagttcagacctttgggctctt
ggatgcattatataccagctcgtggcaggcctaccaccattccgagccggaaatgaatat
ctaatatttcagaagatcattaagttggaatatgactttcctgaaaaattctttcctaag
gcaagagaccttgtggaaaaactgctggttttagatgctacaaagcgattaggctgtgaa
gaaatggaagggtacagccctctgaaagctcatccgttcttcgagtccatcacatgggag
aatctgcatcaccagacgcctccgaagctcacagcttacttgccagccatgtcagaagac
gacgaagactgctatggaaactacgacaatctcctgagccagtttggctgcatgcaggtg
tcctcatcatcctcctcccactccctgtcagctgcggatgcagggcttccacagagggca
ggcagcaacatcgagcagtatatccacgacctggacactaactcttttgagctggactta
cagttttctgaagatgagaagaggttgttattggagaagcaggccagtggaaacccttgg
caccagtttgtagaaaataatttaatactaaaaatgggtccagtagataagcgaaagggt
ttatttgcacggcgacgacagttactgctcacagaagggccacacttatattatgtggat
cctgtcaacaaagtcttgaaaggtgaaattccatggtcgcaagaactccgaccagaggcc
aaaaattttaaaaccttctttgtccacacgccgaataggacgtattacctgatggacccg
agtgggaatgctcacaaatggtgcaaaaagatccaggaggtgtggaggcacagatatcag
agccacccagacgccgctgtgcagtga
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