KEGG   Vicugna pacos (alpaca): 102528555
Entry
102528555         CDS       T08098                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X2
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc00670  One carbon pool by folate
vpc00790  Folate biosynthesis
vpc01100  Metabolic pathways
vpc01240  Biosynthesis of cofactors
vpc01523  Antifolate resistance
vpc04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    102528555 (DHFR)
   00670 One carbon pool by folate
    102528555 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    102528555 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102528555 (DHFR)
Enzymes [BR:vpc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     102528555 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 102528555
NCBI-ProteinID: XP_006197675
UniProt: A0A6I9HWQ5
LinkDB
Position
3
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTASSAEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRELKEPPQGAHFLANSLDDALKVIEQPELTNKVDMVWIVGGSS
VYKEAMDKPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLSEYPGVPSDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctgaactgcatcgttgctgtgtcccagaacatgggtatcggcaagaac
ggggacctcccctggcccccgctcaggaatgaattcaagtatttccagagaatgaccaca
gcctcttcagcagaaggtaaacagaatttggtgattatgggtagaaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaatttagttctcagtagagaactc
aaggaaccaccacaaggagctcattttcttgccaacagtctggatgatgccttaaaagtt
attgagcaaccagaattaacaaataaagtggacatggtttggatagtgggggggagttct
gtttataaggaagctatggacaagccaggccatcttagattatttgtgacaaggatcatg
caggaatttgagagtgacacattttttccagaaattgatctggaaaaatataaacttctt
tcagaatatccaggtgttccttctgatgtccaggaggagaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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