KEGG   Vicugna pacos (alpaca): 102532580
Entry
102532580         CDS       T08098                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc01522  Endocrine resistance
vpc04110  Cell cycle
vpc04115  p53 signaling pathway
vpc04151  PI3K-Akt signaling pathway
vpc04218  Cellular senescence
vpc04530  Tight junction
vpc04660  T cell receptor signaling pathway
vpc04933  AGE-RAGE signaling pathway in diabetic complications
vpc04934  Cushing syndrome
vpc05160  Hepatitis C
vpc05162  Measles
vpc05163  Human cytomegalovirus infection
vpc05164  Influenza A
vpc05165  Human papillomavirus infection
vpc05166  Human T-cell leukemia virus 1 infection
vpc05167  Kaposi sarcoma-associated herpesvirus infection
vpc05169  Epstein-Barr virus infection
vpc05200  Pathways in cancer
vpc05203  Viral carcinogenesis
vpc05212  Pancreatic cancer
vpc05214  Glioma
vpc05218  Melanoma
vpc05219  Bladder cancer
vpc05220  Chronic myeloid leukemia
vpc05222  Small cell lung cancer
vpc05223  Non-small cell lung cancer
vpc05224  Breast cancer
vpc05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    102532580 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    102532580 (CDK4)
   04115 p53 signaling pathway
    102532580 (CDK4)
   04218 Cellular senescence
    102532580 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    102532580 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    102532580 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102532580 (CDK4)
   05203 Viral carcinogenesis
    102532580 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102532580 (CDK4)
   05225 Hepatocellular carcinoma
    102532580 (CDK4)
   05214 Glioma
    102532580 (CDK4)
   05220 Chronic myeloid leukemia
    102532580 (CDK4)
   05218 Melanoma
    102532580 (CDK4)
   05219 Bladder cancer
    102532580 (CDK4)
   05224 Breast cancer
    102532580 (CDK4)
   05222 Small cell lung cancer
    102532580 (CDK4)
   05223 Non-small cell lung cancer
    102532580 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102532580 (CDK4)
   05160 Hepatitis C
    102532580 (CDK4)
   05164 Influenza A
    102532580 (CDK4)
   05162 Measles
    102532580 (CDK4)
   05163 Human cytomegalovirus infection
    102532580 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102532580 (CDK4)
   05169 Epstein-Barr virus infection
    102532580 (CDK4)
   05165 Human papillomavirus infection
    102532580 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102532580 (CDK4)
   04934 Cushing syndrome
    102532580 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102532580 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102532580 (CDK4)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     102532580 (CDK4)
Protein kinases [BR:vpc01001]
 Serine/threonine kinases: CMGC group
  CDK family
   102532580 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 102532580
NCBI-ProteinID: XP_006218037
UniProt: A0A6J3AD92
LinkDB
Position
Unknown
AA seq 303 aa
MTTPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGSGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atgactacccctcgatatgagccagtggctgagattggtgttggtgcctatgggactgtg
tacaaagcccgtgatccccacagtggccactttgtggccctcaagagcgtgagagttccc
aatggaggaggctctggagggggcctgcccatcagcacagttcgtgaggtggccttattg
cggcgcctggaggcttttgagcatcccaatgttgtaaggctgatggacgtctgtgccaca
gcccgaactgaccgggagaccaaagtgaccctggtatttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccaccaggcttgccagtggagaccatcaaggatctg
atgcgccagttcctaagaggcctagatttccttcatgccaactgcattgttcaccgagac
ctgaagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggc
ctggccaggatctacagctaccagatggcacttacacctgtggtggttacactctggtac
cgtgctccggaagttcttctgcagtctacgtatgcaacacctgtggacatgtggagcgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctgttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgattgggctgcccccagaggatgactggccccga
gatgtgtctctgccccgaggagccttttcccccagaggaccgcgcccagtgcagtcagtg
gttcctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacataaggcagaaggt
aacccagagtga

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