Vicugna pacos (alpaca): 102533840 Help Entry 102533840         CDS       T08098                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism vpc  Vicugna pacos (alpaca) Pathway vpc04022   cGMP-PKG signaling pathway vpc04068   FoxO signaling pathway vpc04081   Hormone signaling vpc04140   Autophagy - animal vpc04150   mTOR signaling pathway vpc04151   PI3K-Akt signaling pathway vpc04152   AMPK signaling pathway vpc04211   Longevity regulating pathway vpc04213   Longevity regulating pathway - multiple species vpc04722   Neurotrophin signaling pathway vpc04910   Insulin signaling pathway vpc04920   Adipocytokine signaling pathway vpc04923   Regulation of lipolysis in adipocytes vpc04930   Type II diabetes mellitus vpc04931   Insulin resistance vpc04932   Non-alcoholic fatty liver disease vpc04935   Growth hormone synthesis, secretion and action vpc04960   Aldosterone-regulated sodium reabsorption vpc05010   Alzheimer disease vpc05206   MicroRNAs in cancer vpc05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:vpc00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102533840 (IRS1)    04022 cGMP-PKG signaling pathway     102533840 (IRS1)    04151 PI3K-Akt signaling pathway     102533840 (IRS1)    04152 AMPK signaling pathway     102533840 (IRS1)    04150 mTOR signaling pathway     102533840 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102533840 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102533840 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102533840 (IRS1)    04923 Regulation of lipolysis in adipocytes     102533840 (IRS1)    04920 Adipocytokine signaling pathway     102533840 (IRS1)    04935 Growth hormone synthesis, secretion and action     102533840 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102533840 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     102533840 (IRS1)   09149 Aging    04211 Longevity regulating pathway     102533840 (IRS1)    04213 Longevity regulating pathway - multiple species     102533840 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102533840 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     102533840 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102533840 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102533840 (IRS1)    04932 Non-alcoholic fatty liver disease     102533840 (IRS1)    04931 Insulin resistance     102533840 (IRS1) SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  102533840 NCBI-ProteinID:  XP_031533796 UniProt:  A0A6J3AMF2 LinkDB All DBs Position 5 AA seq 1241 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLAAPN GHYILPRGGNGHRYIPGAGLGTSPALTGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRVPSYRHSAFVPTHSYPEEGLEMHPLERRGGHHR PDTSSLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDLGGGPGSGGSGSGAAPSGSSYGKMWTNGVGGHHSHALPHPKLPVES SSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EESARHQHLRLSSSSGRLLYATAAEDSSSSTSSDSLGGGYCGARLEPSLPHLHHQVLQPH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQQPPPPLLHPPEPKSPGEYVNIEF GSDQPGYLSGPVAPHSSPSVRCPSQLQPAPREEEAGAEEYMNMDLGPGRRATWQESAGVQ PGRVGPAPPGAASMCRPTRAVPSSRGDYMTMQMGCPHQSYVDTSPVAPISYADMRTGIVV EEASLPGATAAAPSSSSTTSAPPAAPQGAGELAACSSLLGGPQGPGGPSAFTRVNLSPSR NQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTLPFGGGAAVGGSGGGSSSAEDVKRH SSASFENVWLRPGELGGAPKELAQVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQP PPPPTPHQPLGSGESSSTSRSSEDLSAYASISFQKQPEDLQ NT seq 3726 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctcccgagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc ccggcgcgtctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtagccctctacacccgggacgagcactttgccatcgcggcggacagcgag gcggagcaggacagctggtaccaggccctcctgcagctgcacaaccgagccaagggccac cacgacggggccgcggcccccggggcgggaggcggcgggggcagctgcagtggcagctct ggcctcggcgaggctggggaggacttgagctacggggacgtgcccccaggacccgccttc aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagctttgtgaagctgaactcggag gcggcggctgtggtgctgcagctgatgaacatcaggcgctgtgggcactccgagaacttc ttcttcatcgaggtgggccgttccgcagtgacgggacccggggagttctggatgcaggtg gatgactctgtggtggcccagaacatgcacgagacaatcctggaggccatgcgggccatg agcgatgagtttcgacctcgaagcaagagccagtcctcctccaactgctccaaccccatc agtgtccccctgcgcaggcaccacctcaacaaccctccacccagccaggtagggctgacc cgccgctctcgcaccgagagcatcactgccacctcccctgccagtttggtgggcgggaag cagggctccttccgcgtccgtgcctccagtgatggcgaaggcaccatgtctcgccccgcc tctgtggacggtagtcctgtaagtcctagcaccaacaggacccacgcccaccggcatcga ggcagctcccggctgcacccgcctctcaaccacagccgctctatccccatgccttcttct cgctgctcaccttccgccaccagcccggtcagtctgtcgtctagcagcaccagtggccac ggatccacctcggactgtctcttcccgcggcggtccagtgcttctgtgtccggttccccc agcgatggcggtttcatctcctcagatgagtatggctccagtccctgcgatttccgaagt tcctttcgtagtgtcactccggattccctgggccacaccccaccggcccgcggtgaggag gagctgagcaactacatctgcatgggaggcaaggggccctccaccctcgctgcccccaac ggtcactacattttgcctcggggtggcaacggtcaccgctacatcccaggagctggtttg gggacgagcccagccctgactggagatgaagcagccagtgccgcggatctggataatcgg ttccgaaagcgaactcactctgctggcacatccccaactatttcccaccagaagacccca tcccagtcctctgtggcttccattgaggaatatacagagatgatgcctgcctacccgcca ggaggtggcagtggaggccgagtgcccagctaccggcactccgccttcgtgcccacccat tcctaccctgaggagggtctagaaatgcaccccctggagcggcgtgggggccaccaccgc ccagacacctccagcctccacactgatgacggctacatgcccatgtccccaggggtggct ccagtgcccggcagccgaaagggcagtggagactacatgcccatgagccccaagagcgtg tctgccccacaacagatcatcaaccccatcagacgccatcctcagagagtggaccccaat ggctacatgatgatgtccccaagcggcagctgctctcctgaccttggaggtgggcctggc agtggcggcagcggcagcggtgcagccccttctgggagcagctatggcaaaatgtggaca aacggggtaggaggccaccactctcacgccctgccacaccccaaactccccgtggagagc agtagtggcaagctcttgtcttgtacaggtgactacatgaacatgtcgccagtgggggat tccaacaccagcagcccttccgactgctactatggccctgaggatccccagcacaagcca gtcctctcctactactccttgccaaggtcctttaagcacacccagcgcccgggagagctg gaggagagcgcccggcaccagcacctccgcctctcctccagctctggtcgactcctctat gccacagcggcagaagattcctcctcctccaccagcagcgacagcctgggcgggggatac tgtggggctaggctggagcccagcctcccgcatctccaccatcaggtcctgcagccccat ctgcctcgaaaggtggacacagctgcccagaccaacaaccgcctggcccggcccacgagg ctgtccctgggggatcccaaggccagcaccttacctcgggccagagagcagcagccgccg ccacccttgctgcaccctccggagcccaagagcccaggggaatatgtgaatattgaattc gggagcgatcagcccggctacttatctggcccggtggctccccacagctcgccttctgtc aggtgcccatcccagctccagccagctcccagagaggaagaggctggcgcggaagagtac atgaacatggacctggggcccggcaggagggccacctggcaggagagcgcaggggtccag cccgggagggtgggccccgccccccccggagctgctagcatgtgccggccgacccgggca gtgcctagcagccggggtgactatatgaccatgcagatgggctgcccccatcagagctac gtggacacctcgccggttgcccccatcagctacgccgatatgcggaccggcatcgttgtg gaggaggccagccttcccggggccacagcggccgcgccctcctcatcctccacgacctct gctccccctgcagcgcctcaaggagcaggggagctggcggcctgctcgtccctgctgggg ggcccgcagggacctgggggcccgagcgccttcacgcgggtgaacctcagtcccagccgt aaccagagtgccaaagtgatccgtgccgacccgcaagggtgcaggaggaggcacagctcc gagaccttctcctcaacgcccagtgccactcgggcgggcaacaccctgcccttcggaggc ggggctgcagtcgggggcagtggtggtggcagcagcagcgctgaggatgtgaagcgccac agctctgcttcctttgagaacgtatggctgaggcctggggagctggggggagcccccaag gagctggctcaagtgtgcggggcagccgggggtttggagaatggtcttaactacatagac ctggatctggtcaaggacttcaaacagcgccctcaggagagaccccctcaaccgcagcct cctccacccccgaccccccatcagcctctgggcagcggcgagagcagctccaccagccgc tccagcgaggatttaagcgcctatgccagcatcagtttccagaagcagccagaggacctc cagtag

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