KEGG   Vicugna pacos (alpaca): 102539136
Entry
102539136         CDS       T08098                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein precursor
  KO
K13375  transforming growth factor beta-1
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04010  MAPK signaling pathway
vpc04060  Cytokine-cytokine receptor interaction
vpc04068  FoxO signaling pathway
vpc04110  Cell cycle
vpc04148  Efferocytosis
vpc04218  Cellular senescence
vpc04350  TGF-beta signaling pathway
vpc04380  Osteoclast differentiation
vpc04390  Hippo signaling pathway
vpc04518  Integrin signaling
vpc04659  Th17 cell differentiation
vpc04672  Intestinal immune network for IgA production
vpc04926  Relaxin signaling pathway
vpc04932  Non-alcoholic fatty liver disease
vpc04933  AGE-RAGE signaling pathway in diabetic complications
vpc05140  Leishmaniasis
vpc05142  Chagas disease
vpc05144  Malaria
vpc05145  Toxoplasmosis
vpc05146  Amoebiasis
vpc05152  Tuberculosis
vpc05161  Hepatitis B
vpc05166  Human T-cell leukemia virus 1 infection
vpc05200  Pathways in cancer
vpc05205  Proteoglycans in cancer
vpc05210  Colorectal cancer
vpc05211  Renal cell carcinoma
vpc05212  Pancreatic cancer
vpc05220  Chronic myeloid leukemia
vpc05225  Hepatocellular carcinoma
vpc05226  Gastric cancer
vpc05321  Inflammatory bowel disease
vpc05323  Rheumatoid arthritis
vpc05410  Hypertrophic cardiomyopathy
vpc05414  Dilated cardiomyopathy
vpc05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102539136 (TGFB1)
   04350 TGF-beta signaling pathway
    102539136 (TGFB1)
   04390 Hippo signaling pathway
    102539136 (TGFB1)
   04068 FoxO signaling pathway
    102539136 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102539136 (TGFB1)
   04518 Integrin signaling
    102539136 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102539136 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    102539136 (TGFB1)
   04218 Cellular senescence
    102539136 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102539136 (TGFB1)
   04672 Intestinal immune network for IgA production
    102539136 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102539136 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102539136 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102539136 (TGFB1)
   05205 Proteoglycans in cancer
    102539136 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102539136 (TGFB1)
   05212 Pancreatic cancer
    102539136 (TGFB1)
   05225 Hepatocellular carcinoma
    102539136 (TGFB1)
   05226 Gastric cancer
    102539136 (TGFB1)
   05220 Chronic myeloid leukemia
    102539136 (TGFB1)
   05211 Renal cell carcinoma
    102539136 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102539136 (TGFB1)
   05161 Hepatitis B
    102539136 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102539136 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102539136 (TGFB1)
   05144 Malaria
    102539136 (TGFB1)
   05145 Toxoplasmosis
    102539136 (TGFB1)
   05140 Leishmaniasis
    102539136 (TGFB1)
   05142 Chagas disease
    102539136 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    102539136 (TGFB1)
   05321 Inflammatory bowel disease
    102539136 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102539136 (TGFB1)
   05414 Dilated cardiomyopathy
    102539136 (TGFB1)
   05415 Diabetic cardiomyopathy
    102539136 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102539136 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102539136 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:vpc03110]
    102539136 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:vpc04052]
    102539136 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:vpc00536]
    102539136 (TGFB1)
Chaperones and folding catalysts [BR:vpc03110]
 Intramolecular chaperones
  Others
   102539136 (TGFB1)
Cytokines and neuropeptides [BR:vpc04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   102539136 (TGFB1)
Glycosaminoglycan binding proteins [BR:vpc00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   102539136 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 102539136
NCBI-ProteinID: NP_001277000
UniProt: A0A6I9GZQ1 W6CMW4
LinkDB
Position
11
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENGDKI
YDKIKRSPHSIYMLFNTSEVREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTHREEIEGFRLSAHCSCDSKDNTLQVDINGFS
SGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccactgctgctgccgctgctgtggctgctagtg
ctgacgcctggtcggccggccgccggactatccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcatcgaggccatccgcggccagattctgtccaagcttcggctcgcc
agccccccgagtcagggggaggtgccgcccggcccgctgccggaggccgtactggccctt
tacaacagtacccgcgaccgggtggccggggaaagtgccgaacccgagcccgagccagag
gcggactactacgccaaggaggtcacccgcgtgctgatggtggaaaacggcgacaaaatc
tatgataaaatcaagcggagcccacacagcatatacatgctgtttaacacatcggaagtc
cgggaggcggtacccgaacccgtgctgctctctcgggcagagctgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatatagcaacgactcctggcgc
tacctcagcaaccggctgctggccccaagcgactcaccggagtggctgtcctttgatgtc
actggagttgtgcggcagtggctgacccacagagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacactccaagtggacattaacgggttcagt
tctggccgccgaggtgatcttgccaccattcatggcatgaaccggcccttcctgctcctc
atggccaccccgctggagagggcccagcacctgcacagctcccggcaccgccgagccctg
gacaccaactactgcttcagctccacggagaagaactgctgtgtgcggcagctctacatt
gacttccgcaaggacctgggctggaagtggatccatgagcccaagggctaccacgccaat
ttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtcctg
gcgctgtacaaccagcacaaccctggcgcgtcggcggcgccatgctgcgtaccgcaggcg
ctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

DBGET integrated database retrieval system