Vicugna pacos (alpaca): 102543885
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Entry
102543885 CDS
T08098
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00230
Purine metabolism
vpc01100
Metabolic pathways
vpc01522
Endocrine resistance
vpc04015
Rap1 signaling pathway
vpc04020
Calcium signaling pathway
vpc04022
cGMP-PKG signaling pathway
vpc04024
cAMP signaling pathway
vpc04062
Chemokine signaling pathway
vpc04072
Phospholipase D signaling pathway
vpc04081
Hormone signaling
vpc04082
Neuroactive ligand signaling
vpc04114
Oocyte meiosis
vpc04211
Longevity regulating pathway
vpc04213
Longevity regulating pathway - multiple species
vpc04261
Adrenergic signaling in cardiomyocytes
vpc04270
Vascular smooth muscle contraction
vpc04371
Apelin signaling pathway
vpc04540
Gap junction
vpc04611
Platelet activation
vpc04713
Circadian entrainment
vpc04714
Thermogenesis
vpc04720
Long-term potentiation
vpc04723
Retrograde endocannabinoid signaling
vpc04724
Glutamatergic synapse
vpc04725
Cholinergic synapse
vpc04727
GABAergic synapse
vpc04742
Taste transduction
vpc04750
Inflammatory mediator regulation of TRP channels
vpc04911
Insulin secretion
vpc04912
GnRH signaling pathway
vpc04913
Ovarian steroidogenesis
vpc04914
Progesterone-mediated oocyte maturation
vpc04915
Estrogen signaling pathway
vpc04916
Melanogenesis
vpc04918
Thyroid hormone synthesis
vpc04921
Oxytocin signaling pathway
vpc04923
Regulation of lipolysis in adipocytes
vpc04925
Aldosterone synthesis and secretion
vpc04926
Relaxin signaling pathway
vpc04927
Cortisol synthesis and secretion
vpc04928
Parathyroid hormone synthesis, secretion and action
vpc04934
Cushing syndrome
vpc04935
Growth hormone synthesis, secretion and action
vpc04970
Salivary secretion
vpc04971
Gastric acid secretion
vpc04972
Pancreatic secretion
vpc04976
Bile secretion
vpc05032
Morphine addiction
vpc05163
Human cytomegalovirus infection
vpc05166
Human T-cell leukemia virus 1 infection
vpc05200
Pathways in cancer
vpc05207
Chemical carcinogenesis - receptor activation
vpc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102543885 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
102543885 (ADCY8)
04371 Apelin signaling pathway
102543885 (ADCY8)
04020 Calcium signaling pathway
102543885 (ADCY8)
04072 Phospholipase D signaling pathway
102543885 (ADCY8)
04024 cAMP signaling pathway
102543885 (ADCY8)
04022 cGMP-PKG signaling pathway
102543885 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
102543885 (ADCY8)
04081 Hormone signaling
102543885 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
102543885 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
102543885 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102543885 (ADCY8)
04062 Chemokine signaling pathway
102543885 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
102543885 (ADCY8)
04923 Regulation of lipolysis in adipocytes
102543885 (ADCY8)
04912 GnRH signaling pathway
102543885 (ADCY8)
04913 Ovarian steroidogenesis
102543885 (ADCY8)
04915 Estrogen signaling pathway
102543885 (ADCY8)
04914 Progesterone-mediated oocyte maturation
102543885 (ADCY8)
04921 Oxytocin signaling pathway
102543885 (ADCY8)
04926 Relaxin signaling pathway
102543885 (ADCY8)
04935 Growth hormone synthesis, secretion and action
102543885 (ADCY8)
04918 Thyroid hormone synthesis
102543885 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
102543885 (ADCY8)
04916 Melanogenesis
102543885 (ADCY8)
04925 Aldosterone synthesis and secretion
102543885 (ADCY8)
04927 Cortisol synthesis and secretion
102543885 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
102543885 (ADCY8)
04270 Vascular smooth muscle contraction
102543885 (ADCY8)
09154 Digestive system
04970 Salivary secretion
102543885 (ADCY8)
04971 Gastric acid secretion
102543885 (ADCY8)
04972 Pancreatic secretion
102543885 (ADCY8)
04976 Bile secretion
102543885 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
102543885 (ADCY8)
04727 GABAergic synapse
102543885 (ADCY8)
04725 Cholinergic synapse
102543885 (ADCY8)
04720 Long-term potentiation
102543885 (ADCY8)
04723 Retrograde endocannabinoid signaling
102543885 (ADCY8)
09157 Sensory system
04742 Taste transduction
102543885 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
102543885 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
102543885 (ADCY8)
04213 Longevity regulating pathway - multiple species
102543885 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
102543885 (ADCY8)
04714 Thermogenesis
102543885 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102543885 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
102543885 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102543885 (ADCY8)
05163 Human cytomegalovirus infection
102543885 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
102543885 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
102543885 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102543885 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102543885 (ADCY8)
Enzymes [BR:
vpc01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
102543885 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
102543885
NCBI-ProteinID:
XP_031546242
UniProt:
A0A6J3BLK8
LinkDB
All DBs
Position
25
AA seq
1257 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRSGGGG
GGGGGGGSGGSCKASDPVGGGPNHHASQLSGDSALPLYSLGPGERAHSTGGTKVFPERSG
SGSARGSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYF
LGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRK
DTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAIL
AGLGTSLLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETR
RCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVS
ILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEP
RQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDV
DIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSL
LSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHL
AQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKS
NLVCAFIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKT
CCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPE
YFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDSLNHSGEDF
LGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNI
LPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEI
IADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPDKQQCEDKWGHLCALADFSLALTESI
QEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPE
ETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAA
VVLGLVQSLNRQRQKQLLNENNNTGIIKAHYNRRTLLTPSGPEPGAQAEGADKSELP
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atggagctctccgatgtgcgctgcctcagcggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcgggagcggctcgcggccgcagcggctgctgtggcagacg
gcggtgcggcacatcaccgagcagcgcttcattcacgggcaccggagcggcggcggcggc
ggcggcggcggcggcggcgggagcggaggctcctgcaaagcctcggaccctgtaggcggc
ggccccaaccaccacgcgtcgcagctgtccggcgactcagcgctgcccctctactcgctg
ggccccggggagagagcgcacagcaccggcggcaccaaagtcttcccggaacgcagcggg
agcggcagcgccaggggcagcgggggcgggggcgacctgggcttcctgcacctcgactgc
gccccgagcaactcggatttcttcctcagtgggggctatagctaccgaggggtcattttc
cccaccctgcgcaactccttcaagtcccgggatctggagcgcctctaccagcgctacttc
ctgggccagaggcgcaaatcggaggtggtgatgaacgtgctggacgtgctgaccaaactc
accctcttggttctccacttgagcctggcctcggcccccatggacccgctcaagggcatc
ctgctgggcttcttcactggcatagaggtggtgatctgcgccctggtagtggtcaggaag
gacaccacctcgcacacgtacttgcagtacagcggcgtggtcacctgggtggccatgacc
acccagatcttagccgcaggtctcggctacgggctgctgggggacggcatcggctacgtg
ctcttcacgctcttcgccacctacagcatgctgccgctgccgctcacctgggccatcctg
gccggcctgggcacctccttgctgcaggtagtcctccaagtggtcatccccaggctggcg
gtcatttccatcaaccaggttgtggctcaggcagtgttattcatgtgtatgaacacagct
ggcatcttcatcagttacctgtcagaccgggcccagcgccaagccttcctggagacgcgg
aggtgcgtggaggccaggctgcggctggagacggaaaaccaaagacaggagcggcttgtg
ctgtccgtgctcccccggtttgtggtcctggaaatgatcaacgacatgaccaacgtggaa
gacgagcacctgcagcaccaattccatcggatctacatccaccgctatgagaacgtcagt
attctttttgcagatgttaaaggatttaccaacctctccacgaccttgtctgctcaggag
ctggtcaggatgcttaacgagctctttgccagatttgatcgactggcccatgagcatcac
tgccttcgcattaaaatcctgggagactgctactactgcgtttcaggacttcccgagccc
cgccaggaccatgcccactgctgcgtagaaatgggcctcagcatgatcaaaactatcagg
tacgtgcggtcaaggacgaagcacgacgttgacatgcgcatcggaatccactcgggctcc
gtgctgtgtggtgtgctgggcctgcggaagtggcagtttgatgtctggtcttgggatgtg
gacattgcaaacaaacttgaatctggaggaatccccgggaggattcacatttccaaagcc
accctggactgcctcaacggggactataatgtggaagagggccatggaaaagagaggaat
gaattcctgaggaagcacaacatagagacctatttaattaagcagcctgaggacagtcta
ctgtctttgcccgaagacattgtcaaggagtctgtgagctcctcagacaggagaaacagt
ggggcaacgttcacagaaggatcctggagccccgaactgcccttcgataacatagtgggg
aaacagaacactctggctgccctaacaagaaattcaataaatctacttccaaaccatctt
gcacaagctttgcatgtccagtctgggcctgaggagattaacaagagaatagaacatacc
atcgacttgcggagtggcgataaattgagaagagagcatatcaagccattctcactgatg
tttaaagactccagcctggagcacaagtattctcaaatgagggatgaagtattcaagtca
aacttggtctgtgcatttatcgtccttctgtttatcacggcaatacaaagtttgcttcct
tcttcaagggtgatgccaatggccatccagttttccatcctgattatgctgcactcggct
ctggtcctcatcaccactgcagaggattataagtgtttgcccttggtcctccggaaaact
tgctgttggattaatgagacctatttggccagaaacgtcatcatctttgcatccatcttg
attaacttcctgggcgccatcttaaatatcctgtggtgtgattttgacaagtcgataccc
ttgaagaacctgactttcaattcctcagctgtgtttacagatatctgctcctacccagag
tacttcgtcttcacgggggtgctggccatggtgacctgtgcggtttttctccgacttaat
tctgtcctgaagctggctgtgctgctgattatgatcgctatctatgccctgctgactgag
accatctatgcagggctgtttctgcgctacgacagcctgaaccacagtggagaagatttc
ctggggaccaaggaggcatcgctactgctgatggccatgttcctcctcgctgtgttttac
catggacagcagctggaatacaccgcccgcctggacttcctttggcgagtgcaggccaaa
gaggagatcaacgagatgaaggagctgagggagcacaacgagaacatgctgcggaacatc
ctgcccagccacgtggcccgccacttcctggagaaggaccgggacaacgaggagctgtat
tcccagtcctatgatgccgttggggtgatgtttgcctccatcccagggtttgcagacttt
tactctcagactgaaatgaataaccaaggagtggaatgcctacgcctgctgaatgagatc
atcgccgacttcgatgagctgctcggtgaagaccgatttcaagacattgagaagattaag
accattggcagcacctacatggctgtgtctggcctgtcacctgacaaacagcaatgtgaa
gacaagtgggggcatctgtgcgccctggccgacttctctctcgccctgaccgaaagcata
caggagatcaacaagcactctttcaacaatttcgagctccggattggcatcagccacggc
tcagtggtcgctggcgttatcggcgctaagaagccacagtacgacatttggggcaagacc
gtgaacctggcaagtcggatggacagcacgggggtcagcggccggatccaggtcccagag
gagacctatctcatcctgaaggaccagggctttgccttcgactaccgcggggagatctac
gtgaagggcatcagcgagcaggaaggaaaaatcaaaacgtactttctcctgggaagagtc
caacccaacccattcatcctgcccccgagaagactgcccgggcagtactccttggccgcg
gtggtcctgggcctcgtccagtccctcaacaggcagaggcagaagcagctcctgaacgag
aacaacaacacaggcatcatcaaggcccattacaaccggcggactttgctgacgcccagc
gggccggagccgggggcccaggccgaaggcgccgacaagtccgagttgccataa
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integrated database retrieval system
