KEGG   Vicugna pacos (alpaca): 102545164
Entry
102545164         CDS       T08098                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1
  KO
K14381  sequestosome 1
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04137  Mitophagy - animal
vpc04140  Autophagy - animal
vpc04217  Necroptosis
vpc04218  Cellular senescence
vpc04380  Osteoclast differentiation
vpc05014  Amyotrophic lateral sclerosis
vpc05022  Pathways of neurodegeneration - multiple diseases
vpc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102545164 (SQSTM1)
   04137 Mitophagy - animal
    102545164 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    102545164 (SQSTM1)
   04218 Cellular senescence
    102545164 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102545164 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102545164 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    102545164 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    102545164 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vpc04131]
    102545164 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:vpc03029]
    102545164 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:vpc04147]
    102545164 (SQSTM1)
Membrane trafficking [BR:vpc04131]
 Autophagy
  Mitophagy
   Cargo receptors
    102545164 (SQSTM1)
  Pexophagy
    102545164 (SQSTM1)
  Aggrephagy
    102545164 (SQSTM1)
  Xenophagy
    102545164 (SQSTM1)
  ER-phagy
   ER-phagy recepters
    102545164 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    102545164 (SQSTM1)
Mitochondrial biogenesis [BR:vpc03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    102545164 (SQSTM1)
Exosome [BR:vpc04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102545164 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 ZZ PB1
Other DBs
NCBI-GeneID: 102545164
NCBI-ProteinID: XP_006198979
UniProt: A0A6I9HYH8
LinkDB
Position
22
AA seq 378 aa
MLFFHLDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEVPRNMV
HPNVICDGCNGPVVGTRYKCSVCPDYDLCAVCEGKGLHREHSKLAFPSPFGHLSEGFSHS
RWLRKLKHGHFGWPGWEMGPPGNWSPRPPRAGDARPGPAAESASGPSEDPSVNFLKNVGE
SVAAALSPLGIEVDIDVEHGGKRSRLTPASPSGSSTEEKCSSRPSSCSSDPSKPRGDAEG
TAQSLVEQMNKIALESGGQPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESE
GPSSLDPAQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNY
DIGAALDTIQYSKHPPPL
NT seq 1137 nt   +upstreamnt  +downstreamnt
atgctgttctttcatctagatgaggacggggacttggttgccttttccagcgacgaggaa
ctgacaatggcaatgtcatacgtgaaggatgacatcttccgtatttacattaaagagaag
aaggagtgccggcgggaccaccgccctccgtgtgctcaggaggtgccccgcaacatggtg
caccccaacgtgatctgtgatggttgcaacgggcccgtggtggggacccgctacaagtgc
agcgtctgcccagactacgacctctgtgccgtctgcgaggggaagggcctgcacagggag
cacagcaagctggccttccccagccccttcgggcacctttccgagggcttctctcacagc
cgctggctccggaagctgaaacacggccactttgggtggcctggctgggagatgggccca
cctgggaactggagcccgcgtccacctcgagcaggggacgcccgacctggccccgctgcg
gaatcagcttctggcccatcagaggatcccagtgtgaatttcctcaagaatgtaggggag
agtgtggcggctgccctcagccctctgggcattgaggtcgacattgacgtggaacacggc
gggaagcggagccgtctgacacccgcctcccccagcggctccagcacagaggagaagtgc
agctctcggccaagcagctgctcttctgaccccagcaaaccgcgtggggatgcggagggc
acggcccagtctctggtggagcaaatgaacaagattgccctggagtcaggggggcagcct
gaggagcagatggagtctgataactgctcaggaggagacgatgactggactcatttgtct
tcgaaagaggtggacccatctacaggtgaactccagtctctccagatgcccgaatctgag
gggccaagctctctggaccctgcccaggaaggacccacagggctgaaggaagccgcactg
tacccacatctgccaccagaagctgacccccggctgatagagtccctctcccagatgctg
tccatggggttctccgatgaaggcggctggctcaccaggctcctgcagaccaagaactac
gacatcggggctgcgctggacaccatccagtattcaaaacacccaccgccattgtga

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