Vibrio paracholerae: SA104470976_02325
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Entry
SA104470976_02325 CDS
T08432
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
vpl
Vibrio paracholerae
Pathway
vpl00270
Cysteine and methionine metabolism
vpl00450
Selenocompound metabolism
vpl00670
One carbon pool by folate
vpl01100
Metabolic pathways
vpl01110
Biosynthesis of secondary metabolites
vpl01230
Biosynthesis of amino acids
vpl04981
Folate transport and metabolism
Module
vpl_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
vpl00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SA104470976_02325 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SA104470976_02325 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SA104470976_02325 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SA104470976_02325 (metH)
04980 Cobalamin transport and metabolism
SA104470976_02325 (metH)
Enzymes [BR:
vpl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SA104470976_02325 (metH)
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GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
SYZ82394
LinkDB
All DBs
Position
1:complement(2519550..2523230)
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AA seq
1226 aa
AA seq
DB search
MGKEVRQQLEQQLKQRILLIDGGMGTMIQSYKLQEEDYRGARFVDWHCDLKGNNDLLVLT
QPQIIKEIHSAYLEAGADILETNTFNSTTIAMADYDMQSLSAEINFAAAKLAREVADEWT
AKDPGRPRYVAGVLGPTNRTCSISPDVNDPGFRNVTFDGLVEAYSESTRALIKGGSDLIL
IETIFDTLNAKACAFAVDSVFEELGISLPVMISGTITDASGRTLSGQTTEAFYNALRHVR
PISFGLNCALGPDELRQYVEELSRISECYVSAHPNAGLPNAFGEYDLSAEEMAEHIAEWA
QAGFLNLVGGCCGTTPEHIAAIAKAVEGVKPRSLPDLKVECRLSGLEPLNIGPETLFVNV
GERTNVTGSARFKRLIKEEQYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNL
CASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFIAQAKLVRRYGAA
VIVMAFDEVGQADTRERKLEICRRAYHILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYA
LDFINAVADIKRELPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKHGMDMGIVNA
GQLEIYDNVPLKLREAVEDVILNRRSDGTERLLEISEAYRENSVGKEEDASALEWRAWPV
AKRLEHALVKGITEFIVQDTEEARQQASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVV
KSARVMKQAVAYLEPFINALKSGSTSNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIID
LGVMVPCEQILKVAREQNVDIIGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSK
AHTAVKIEQNYHAPVVYVNNASRAVGVCTSLLSDELRPGFIERLDLDYERTRDQHARKTP
KSRPVTLEQARANKAALDWVNYTPPAPAKPGVHVFENIALATLRPYIDWTPFFMTWSLMG
KYPAIFEHEEVGEEAQRLFHDANALLDKVEREGLLKASGMCALFPAASVGDDIEVYSDES
RTQVAHMLYNLRQQTEKPKGANYCLSDYIAPKESGKRDWIGAFAVTGGIGERALADAYKA
QGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYASDENLSNDELIRERYQGIRPAPG
YPACPEHTEKATLWQMLNVEETIGMSLTTSYAMWPGASVSGWYFSHPDSRYFAVAQIQQD
QLHSYAERKGWSLEQAEKWLAPNLDA
NT seq
3681 nt
NT seq
+upstream
nt +downstream
nt
gtgggaaaagaagtaagacaacaactcgaacagcaattgaaacagcgtatcctactgatt
gatggtggtatgggtaccatgattcagagttataagttacaagaggaagactatcgcggt
gcacgatttgtcgattggcactgtgatttgaaaggaaataacgacctcttagtgcttact
cagccgcaaattattaaagagattcactcggcttaccttgaagcgggggcggatattctt
gagaccaacacctttaactcaaccacgattgccatggcagactatgacatgcaatcgctc
agtgccgaaattaactttgccgcggctaagcttgcacgtgaagtcgcggatgagtggacg
gctaaagacccaggtcggccacgttatgtggctggtgtgcttgggccaaccaaccgtact
tgctctatttcgccagatgtgaacgatccgggatttcgtaacgtcacttttgatgggctt
gttgaagcttattccgaatcgacgcgcgctttgatcaagggtggcagcgatctgatcctg
attgaaaccattttcgatacgcttaacgccaaagcctgtgcgtttgcggtcgatagcgta
tttgaagaactgggtatcagcttacctgtgatgatttccggtacgattaccgatgcctct
gggcgtactttgtctggacagacaacagaagcgttctacaacgcgttgcgtcatgttcgg
ccgatttcgtttggtttgaactgtgcgttaggccctgatgagctgcgccagtacgtggaa
gagctttcacgcatttcagaatgctatgtttccgcgcacccgaatgccggactgcccaac
gcgtttggcgaatacgatctctctgccgaggagatggcagaacatattgcggaatgggcg
caagcaggctttcttaacttagtcggtggttgctgtggtacaacacctgagcatatcgcc
gccattgccaaagccgtcgagggtgtaaaaccaaggtctctgccagatctgaaagtagaa
tgtcgtctctcgggtttagagccgctcaatattggccctgaaaccttgtttgttaacgtg
ggcgaacgtactaacgtcaccggttcagcgcgttttaagcgtttaattaaagaagagcaa
tacgacgaagcgctcgatgtggcgcgtgagcaagtcgaaaacggcgcgcagatcattgat
atcaacatggatgaaggcatgttggacgccgaggcgtgcatggtgcgctttttgaatcta
tgcgcctctgaaccagaaatatccaaagttccggtgatggtcgactcctctaaatgggaa
gtcattgaagcgggtctgaaatgcattcagggtaaaggcatcgtcaactcgatttcgctg
aaggaagggaaagagaagtttattgcccaagccaaattggtgcgccgctacggtgccgcg
gtaattgtgatggcgtttgatgaagtgggccaagccgatacccgtgagcgcaaattagag
atctgccgtcgggcttaccatattttagtcgatgaggtgggcttcccaccggaagatatt
attttcgacccgaacatctttgccgttgcgaccggaattgatgagcacaataactatgca
ctggatttcattaatgcagtggcggacattaagcgtgagctgccgcatgcgatgatttct
ggcggtgtgtctaacgtttccttctctttccgcggcaacaactatgtgcgcgaagcgatc
catgctgtattcctttatcactgttttaaacacggcatggatatggggattgtcaacgca
gggcagcttgaaatctacgataacgttccgctgaaactgcgtgaggcagtggaagatgtg
atcctcaatcgacgtagcgatggcacggaaagactgcttgaaatttccgaagcgtatcgc
gaaaacagtgttggtaaagaagaggatgcttctgcgttagagtggcgcgcatggcctgtg
gctaagcgcctagagcacgctttagtcaaaggcatcaccgaatttatcgtccaagacact
gaagaagcgcgtcagcaagccagtaagccgctggaagtgattgaagggccgctgatggat
ggcatgaacgtggtcggtgacttgtttggtgaaggaaaaatgttcttaccgcaagtcgta
aaatcagcgcgtgtcatgaaacaagccgttgcgtaccttgaacctttcattaacgcgcta
aaaagcggtagtacttcaaacggtaaaattttgctggcgaccgtaaaaggcgatgtgcac
gatatcggcaagaacatcgttggtgtggtactgcagtgcaataattatgaaattattgat
cttggcgtgatggtgccttgtgagcaaattcttaaagtcgcgcgcgagcaaaatgtcgat
atcatcggtctctctgggcttatcacgccgtctttggatgaaatggtgcacgtggcgaaa
gagatggagcgacaagggtttgagctgccacttttgattggtggcgcaacaacgtctaaa
gcacatactgcggtgaagatcgaacagaattatcatgcgcctgtggtgtacgtgaataac
gcgtcgcgcgcggtaggggtgtgtacttcactactgtctgatgagctgcgtcctgggttt
atcgagcgtttggacctcgattatgagcgcacgcgtgatcagcatgcacgtaaaacgccc
aaatcgcgcccagtcacgttagagcaggcgcgtgctaataaagcggcgctggattgggta
aattacacgccgcccgctcctgcgaaaccgggtgtgcatgtatttgaaaacattgcgtta
gccacactacgtccttacatcgactggacgcctttctttatgacttggtcgcttatgggc
aaataccctgccattttcgagcatgaagaggtcggtgaagaggctcaacgtctgtttcat
gatgccaatgccttacttgataaagtcgagcgagaaggactactgaaagccagcggcatg
tgtgcactgttcccagcagccagcgtgggcgatgatattgaggtgtacagtgatgaatcg
cgtacgcaagtcgcgcatatgttgtacaacttgcgtcagcagactgagaaaccgaaaggg
gccaactactgtttgtcggactacatcgccccgaaagagagtggtaagcgcgattggatt
ggtgcgtttgcggtaaccggtggcattggtgagcgagcgttggctgatgcttataaagct
cagggcgatgattacaatgcgatcatgatccaagcggtggccgatcgtttggcagaagcc
tttgccgaatatctgcatgaaaaagtgcgtaaagagatttggggttacgcaagcgatgaa
aatctctccaatgatgagctgatccgcgagcgttatcagggcattcgaccagcgccgggg
tatcctgcgtgtcctgagcataccgagaaagcgactttgtggcagatgctgaatgtcgaa
gagaccatcggtatgtcacttaccactagttatgcgatgtggccgggcgcttcagtgtca
ggttggtatttctcgcatcccgattctcgctattttgcggttgcgcagatccaacaagat
cagctgcacagctacgctgagcgtaaaggttggagtttggaacaagccgaaaagtggcta
gcgcctaaccttgatgcttaa
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