Vulpes vulpes (red fox): 112928234
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Entry
112928234 CDS
T05911
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp04120
Ubiquitin mediated proteolysis
vvp04144
Endocytosis
vvp04330
Notch signaling pathway
vvp04668
TNF signaling pathway
vvp04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112928234 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
112928234 (ITCH)
04668 TNF signaling pathway
112928234 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112928234 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112928234 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vvp04131
]
112928234 (ITCH)
04121 Ubiquitin system [BR:
vvp04121
]
112928234 (ITCH)
Enzymes [BR:
vvp01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
112928234 (ITCH)
Membrane trafficking [BR:
vvp04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
112928234 (ITCH)
Ubiquitin system [BR:
vvp04121
]
Ubiquitin ligases (E3)
HECT type E3
112928234 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
112928234
NCBI-ProteinID:
XP_025865648
UniProt:
A0A3Q7T835
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESVPQNDDGSRPKDETRTNTNGS
DEPEDTGTGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggtagtggatcgcagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagc
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtctgtctgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgtt
ccacagaatgatgatggctctagaccgaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatactgggactggtgaaaataggaaggtcaatggaaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaggctcccctaccacctggttgggaacagagagtggaccagcatgggcga
gtttactatgtagatcatattgagaaaagaacaacgtgggatagaccggaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacgtggcagaggccgacactggaatctgtccggaattatgaacagtggcag
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggtcagttaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagttgatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgcactagacaatggaccacag
atagcctatgtacgggacttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacgttgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagatcaatcccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatggaaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactgaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacaaacacaagctttctttgagggcttt
aatgaaatccttccccagcagtatttgcaatactttgacgcaaaggaattagaggtcctt
ttatgcggaatgcaagagattgatttgaacgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttgggaaa
gaaaattggttgcccagaagtcatacctgttttaatcgcctggacctgccaccctacaag
agctatgagcagctgaaggaaaagcttttatttgccattgaagaaacagaaggatttgga
caagagtaa
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