Vulpes vulpes (red fox): 112934273 Help Entry 112934273         CDS       T05911                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism vvp  Vulpes vulpes (red fox) Pathway vvp00230   Purine metabolism vvp01100   Metabolic pathways vvp01522   Endocrine resistance vvp04015   Rap1 signaling pathway vvp04020   Calcium signaling pathway vvp04022   cGMP-PKG signaling pathway vvp04024   cAMP signaling pathway vvp04062   Chemokine signaling pathway vvp04072   Phospholipase D signaling pathway vvp04081   Hormone signaling vvp04082   Neuroactive ligand signaling vvp04114   Oocyte meiosis vvp04211   Longevity regulating pathway vvp04213   Longevity regulating pathway - multiple species vvp04261   Adrenergic signaling in cardiomyocytes vvp04270   Vascular smooth muscle contraction vvp04371   Apelin signaling pathway vvp04540   Gap junction vvp04611   Platelet activation vvp04713   Circadian entrainment vvp04714   Thermogenesis vvp04723   Retrograde endocannabinoid signaling vvp04724   Glutamatergic synapse vvp04725   Cholinergic synapse vvp04727   GABAergic synapse vvp04750   Inflammatory mediator regulation of TRP channels vvp04911   Insulin secretion vvp04912   GnRH signaling pathway vvp04913   Ovarian steroidogenesis vvp04914   Progesterone-mediated oocyte maturation vvp04915   Estrogen signaling pathway vvp04916   Melanogenesis vvp04918   Thyroid hormone synthesis vvp04921   Oxytocin signaling pathway vvp04922   Glucagon signaling pathway vvp04923   Regulation of lipolysis in adipocytes vvp04925   Aldosterone synthesis and secretion vvp04926   Relaxin signaling pathway vvp04927   Cortisol synthesis and secretion vvp04928   Parathyroid hormone synthesis, secretion and action vvp04934   Cushing syndrome vvp04935   Growth hormone synthesis, secretion and action vvp04970   Salivary secretion vvp04971   Gastric acid secretion vvp04972   Pancreatic secretion vvp04976   Bile secretion vvp05032   Morphine addiction vvp05163   Human cytomegalovirus infection vvp05166   Human T-cell leukemia virus 1 infection vvp05200   Pathways in cancer vvp05207   Chemical carcinogenesis - receptor activation vvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:vvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112934273 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112934273 (ADCY2)    04371 Apelin signaling pathway     112934273 (ADCY2)    04020 Calcium signaling pathway     112934273 (ADCY2)    04072 Phospholipase D signaling pathway     112934273 (ADCY2)    04024 cAMP signaling pathway     112934273 (ADCY2)    04022 cGMP-PKG signaling pathway     112934273 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112934273 (ADCY2)    04081 Hormone signaling     112934273 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112934273 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     112934273 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112934273 (ADCY2)    04062 Chemokine signaling pathway     112934273 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     112934273 (ADCY2)    04922 Glucagon signaling pathway     112934273 (ADCY2)    04923 Regulation of lipolysis in adipocytes     112934273 (ADCY2)    04912 GnRH signaling pathway     112934273 (ADCY2)    04913 Ovarian steroidogenesis     112934273 (ADCY2)    04915 Estrogen signaling pathway     112934273 (ADCY2)    04914 Progesterone-mediated oocyte maturation     112934273 (ADCY2)    04921 Oxytocin signaling pathway     112934273 (ADCY2)    04926 Relaxin signaling pathway     112934273 (ADCY2)    04935 Growth hormone synthesis, secretion and action     112934273 (ADCY2)    04918 Thyroid hormone synthesis     112934273 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     112934273 (ADCY2)    04916 Melanogenesis     112934273 (ADCY2)    04925 Aldosterone synthesis and secretion     112934273 (ADCY2)    04927 Cortisol synthesis and secretion     112934273 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112934273 (ADCY2)    04270 Vascular smooth muscle contraction     112934273 (ADCY2)   09154 Digestive system    04970 Salivary secretion     112934273 (ADCY2)    04971 Gastric acid secretion     112934273 (ADCY2)    04972 Pancreatic secretion     112934273 (ADCY2)    04976 Bile secretion     112934273 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     112934273 (ADCY2)    04727 GABAergic synapse     112934273 (ADCY2)    04725 Cholinergic synapse     112934273 (ADCY2)    04723 Retrograde endocannabinoid signaling     112934273 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112934273 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     112934273 (ADCY2)    04213 Longevity regulating pathway - multiple species     112934273 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     112934273 (ADCY2)    04714 Thermogenesis     112934273 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112934273 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     112934273 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112934273 (ADCY2)    05163 Human cytomegalovirus infection     112934273 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     112934273 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112934273 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112934273 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112934273 (ADCY2) Enzymes [BR:vvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112934273 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  112934273 NCBI-ProteinID:  XP_025873464 UniProt:  A0A3Q7T8Q6 LinkDB All DBs Position Unknown AA seq 1051 aa AA seqDB search MSQQHPLIVFLLLIVMGACLALLAVFFALRLEVEEHVAFLITVPTALAIFFAIFILVCIE SVFKKLLRLFSLVIWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAI IASVLTSASHTIVLSVCLSATPGTKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQT YQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFH NLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGD CYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQ KWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVK TYFVINPKGERRSPHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTEN GKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRIS LLFYNKILEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSILGISFGAAFLLLA FILFICFAGQLLQCSKKASASLLWLLKSSGIIADRPWPRVSLTVLTTAIILTMAVFNMFF LSDPEETIPPTANTSNMSLSALSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYE LKMLIMMVALVAYNTILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVL GRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYH QSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKT IGSTYMAATGLSAVPSQEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVG INHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSVILQTLGYACTCR GIINVKGKGELKTYFVNTEMSRSLSQSNLAS NT seq 3156 nt NT seq  +upstreamnt  +downstreamnt atgagccagcagcacccgctcatcgtgttcctgctgctcatcgtcatgggcgcctgcctc gccctgctcgccgtcttcttcgcgctccggctggaagttgaagaacacgtggcgttttta ataacggtcccgacggccctggcaattttctttgcaatattcatcctcgtctgcattgag tctgtgttcaaaaagctgctccgccttttctccttggtgatatggatatgtctcgtggcc atggggtacctgttcatgtgctttggaggcaccgtctctccctgggaccaggtgtcgttc ttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagatgccatc atcgccagcgtgctcacctccgcctcccacaccatcgtgctgagcgtctgcctgtccgcg acgccggggaccaaggagcacctggtctggcagatcctggccaatgtgatcattttcatc tgtgggaacctggcgggggcataccacaagcacctcatggaacttgccctgcagcagaca tatcaggacacatgcaattgcatcaagtcccggatcaagctggaatttgaaaagcgtcag caggaacggcttttgctctctctgctgcctgctcacatagccatggaaatgaaagctgag atcatccagaggcttcagggccccaaagccggccaaatggaaaacacaaacaactttcac aacctgtatgtcaagcgacacaccaatgtgagtatcctgtatgctgacattgttggcttc acccggctggccagtgactgctccccaggagagctggtccacatgctgaacgagctgttt ggaaagtttgatcaaattgcaaaggagaatgaatgcatgagaataaaaattttgggagac tgctactattgtgtatccggactccctatatctctcccaaaccatgccaagaactgtgtg aaaatggggctggacatgtgtgaagccataaagaaggtgagggatgcgactggcgtggat attaacatgcgcgtgggagtgcattccgggaacgtcctttgcggggtgatcggcctgcag aagtggcagtacgacgtgtggtcacacgacgtgaccctggccaatcacatggaggctgga ggggtccctggacgtgttcacatttcttctgtcaccctggaacacttaaacggcgcttat aaagtggaggagggagacggtgacatcagagacccgtatttaaagcagcacctggtgaag acctactttgtaatcaaccccaagggagaacgaaggagtcctcacctcttcagacctcgc cacaccctcgatggagccaagatgagggcttctgtgcgcatgacccggtacctggagtcc tggggagcggccaagccctttgcacacctgcatcatcgagacagcatgaccacagagaat ggcaagatcagcacaacggatgtgccaatgggtcagcataatttccaaaatcgtacctta agaaccaagtcccaaaagaaaagatttgaagaagaattaaatgaaaggatgattcaagca attgatggaattaatgcacaaaagcagtggctcaagtctgaagacattcagagaatctca ctcctgttctacaataaaatactagaaaaagaataccgagccactgcactgccagcgttt aagtactacgtcacctgcgcctgtctcatattcttctgcatctttattgtacagattctg gtattaccaaaaacatcgattctggggatctcctttggagctgcatttctcctgctcgcc tttatccttttcatctgctttgctggacagcttttgcaatgcagcaagaaggcatccgcc tctctcctgtggctgttgaagtcgtcgggcatcatcgccgaccggccctggccgcgggtc tccctcaccgtcctcaccacggccatcattctgaccatggccgtgttcaacatgtttttc ctgagtgatccagaggaaacaattcctccaactgccaatacatcaaacatgagtctgtct gccttaagtaatcaggcagcgattctgcgtgcacaaaatctgtttttcctcccgtacttt atctacagctgcattctgggtttgatttcctgctcggtgttcctgcgggtgaattacgag ttgaaaatgttgatcatgatggtggcattggtggcctacaacaccatcctcctgcacact cacgcccacgtcctggacgactacagccaggtcttattcgagagaccaggcatttggaaa gacctgaagaccatgggctcagtgtctctctttatattcttcatcacactgcttgttctg ggtagacagaatgaatattactgtaggttagacttcttatggaagaacaaattcaaaaaa gaacgggaggagatagagaccatggagaacctgaaccgtgtgctgctggagaacgtgctg cccgcacatgtggccgagcatttcctggcccggagcctgaagaacgaggacttataccac caatcctatgactgtgtctgcgtcatgtttgcctccattccggatttcaaagaattctac acagaatcagatgtgaacaaggagggtttggaatgccttcggctcctgaatgagatcatt gccgactttgatgatctgctgtccaagccaaaattcagtggagttgaaaagatcaagacc attggcagcacatacatggcagcgaccggtctgagcgccgtgcctagccaggagcatgcc caggagcccgagaggcagtacatgcacattggcaccatggtggagtttgcctttgccctg gtggcgaaactggatgctatcaacaagcactccttcaatgacttcaagttgcgagtgggt attaaccatggacctgtaatagctggtgtgattggagcccagaagccacagtatgatatc tggggtaacacggtgaacgtggccagcaggatggacagcaccggcgtgctggacaaaata caggtcaccgaggagaccagcgtcatccttcagaccctggggtacgcatgcacgtgtcga gggataatcaacgtgaaaggcaaaggggagctgaagacgtactttgtaaacacggaaatg tcaaggtccctttcccagagcaacttggcatcctga

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