KEGG   Waddlia chondrophila: wcw_1827
Entry
wcw_1827          CDS       T01255                                 
Symbol
acrB
Name
(GenBank) multidrug-efflux transport protein
  KO
K18138  multidrug efflux pump
Organism
wch  Waddlia chondrophila
Pathway
wch01501  beta-Lactam resistance
wch01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:wch00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    wcw_1827 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    wcw_1827 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:wch02000]
    wcw_1827 (acrB)
   01504 Antimicrobial resistance genes [BR:wch01504]
    wcw_1827 (acrB)
Transporters [BR:wch02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   wcw_1827 (acrB)
Antimicrobial resistance genes [BR:wch01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    wcw_1827 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C
Other DBs
NCBI-ProteinID: ADI39166
UniProt: D6YSX1
LinkDB
Position
complement(1955335..1958454)
AA seq 1039 aa
MFSHFFIDRPILSSVISIVIVLAGFMAMVNLPIAQYPEITPRQVQVTTAYPGASAEVVSN
NVAAPIEQQVNGADDMLYMYSSCSSTGNMTLNVFFDLSRDPDLAQVDVQNRVNLALPQLP
EIVTRQGVSVKKVSTSFMMIIAVFSPDGRYDNTYVGNYANLYILDAIKRIPGANQASVIG
VPDYAMRLWVKPDRMAQLGITSQDIIRAVQAQNEQFAAGRVGQPPNMDEVVMTFPVTTQG
RLTTPQEFEEIILRAGSEGAAIVKLKDIGRAELGSKDYNVTTHLNKMPATLIAVYQQPGS
NALEVSEAVTSLLKEMKKDFPDGIDYKISMDTTQFVRASIHEVVRTFFEAAVLVTLVVLI
FLGTIRATLIPLVAVPISILGAFIGMILMGFSINMLTLFGLILAIGVVVDDAIVVMENVE
RNMAAFKLSPREAARRAMVEVTGPVIATTLVVLAVFIPVGFMGGVTGELYKQFAITIAIS
VGFSSIVALTLSPALTVILLTPDMKKKGFFQWFDRKFDWINEKYASLVEFFLNNKLISAG
VFIVAIISSWWMFATISTSFVPEEDQGYLLSVYMLPDASSLDRTAEVGRQVEKIFLDQPG
VSDVATGNGYSLLDGQLKTNTGVAFVALDDYEKRKSPDLQAEHIMRATGAKMMQIREGVA
FPINPPPIPGLGSVGGFEFWVQSQGTGTYQQLGEVINKVVEKAGERPELGNLTATINTDS
QQLFVNLDRERAEVYGVPVQEVYDTLQTLFGSIYVSQFSKFSRLWQVIVQAESSYRTVPE
DINQVYVRNKNNDMVPLSSLVSMEYVAGPDIVTRFNNFPAAKINGNPAPGYSSGQALNAM
EEVAREVFPPGYGFAWSGQAFEEKKSGGTSAVAFIFGMVMVFLILAAQYERWSMPFAVIL
ALPFALFGALLAIWLRGISNDVYFQIGMVALIALAAKNAILIVEFAMQKYEEGFSAYESA
LIAAKLRLRPICMTAFSFILGCVPLAMATGASANSRHSIGTGVIGGMLGATVIAIFFIPL
FYLLLQKISGDHKEKSDEE
NT seq 3120 nt   +upstreamnt  +downstreamnt
atgttttctcatttttttatcgacaggcccattctatcttccgtgatctccattgtgatt
gtgcttgcaggtttcatggcaatggtgaacttgccgattgcgcaatatccggagatcacg
ccgcgccaggttcaggtgacgacagcttatcccggtgcaagcgcagaagtggtctctaat
aacgtcgcagccccgatagagcagcaggtgaacggcgccgatgatatgctttatatgtat
tcctcctgctcttctaccggaaatatgacgcttaatgtgtttttcgatctgtcgcgggat
ccagaccttgcacaagtcgatgtgcaaaatcgagtaaaccttgctttgccgcagcttcct
gaaattgtcacacggcagggggtctcggtcaaaaaggtttcgacgagttttatgatgatc
attgcggtgttctctcccgatgggcggtatgacaacacgtatgtcggcaactatgccaat
ttatatattcttgatgcgatcaaacgaattcctggggcaaaccaagcttctgtcatcgga
gtgcccgattatgctatgagactgtgggtcaaaccggatcggatggcacagctgggaatc
acttcgcaggacattatcagagctgttcaggcgcagaatgaacagtttgccgcgggaaga
gtcgggcagcctcctaatatggatgaggttgtgatgactttccctgtaacaactcaagga
aggttgacaacacctcaggagtttgaagagatcattcttcgtgccggatcggaaggggct
gccattgtcaagctcaaagatatcggtagagcggaattggggtcaaaagactacaatgtg
acaacgcatctcaacaaaatgccagcaacactgattgctgtctatcagcagcctggatcg
aatgccttggaagtttctgaagctgtgacttcgcttctcaaagagatgaaaaaagatttt
cccgatggcattgattataaaatttccatggacacgacgcaatttgtgagagcgtctatt
cacgaagtggtcaggacattttttgaagctgctgttttagtgacattggttgttttgatc
tttttgggaacgatccgtgcgaccctgattcctctagtcgctgttcctatttctatatta
ggtgcgttcattggaatgatcctcatgggattttccattaatatgctgacgctttttggc
ctgatcctggctatcggagtggttgttgacgatgccatcgtcgtgatggaaaacgtggaa
agaaatatggcggcgttcaaactctctccgcgagaagcggcgaggcgcgccatggtggag
gtgactggacctgtaatcgcaaccactcttgttgtccttgcagtgttcattcctgtcgga
tttatgggaggagtgacaggagagctttataagcagtttgcgattacaattgcaatttct
gttggattttcatcgattgttgctttgactttgtctccggctctgaccgtcattttgtta
acccctgacatgaagaaaaaaggatttttccagtggttcgataggaaatttgattggatt
aatgaaaaatatgcatcccttgtggaattttttcttaacaataaattgatttcagccggg
gttttcattgtagcgatcatcagttcatggtggatgttcgcgacgatatccacaagtttt
gtgcctgaagaagaccagggatatttgcttagcgtgtacatgctccccgatgcatccagc
cttgatcgaacggcagaagtgggaagacaggtggaaaaaatctttttggatcagcctggg
gttagtgatgtggcaacgggtaatggctatagtttgttggatggtcaattaaaaacaaat
actggggttgcctttgtcgcgttggatgattacgaaaaaaggaaaagtccggatctgcag
gcagagcatatcatgcgggcaacaggagcgaaaatgatgcagatcagagagggggtggct
tttccgatcaatcctcctcctattccaggcctaggcagcgtgggtggtttcgagttttgg
gtgcagagtcaaggaacgggaacctatcaacagctaggtgaagtgatcaataaggtggtc
gaaaaggctggtgaacgacctgagcttgggaatttgaccgcgacgattaatactgattca
cagcagctgtttgtcaatctagacagggagagggctgaggtttatggagttccggtgcag
gaggtctatgatactttgcaaactctgttcggttccatttatgtgagtcaattcagtaaa
ttcagccgtttgtggcaggtgatcgtgcaggcggagtcatcatatcgaacagtgccggaa
gatattaatcaagtctatgtccgcaacaaaaacaacgacatggtgccgctctcctctctt
gtctcaatggagtatgtcgcaggcccggacattgtgacgcgctttaataattttcctgca
gcaaaaattaatgggaatccagctcccggctacagttcagggcaggctttaaatgcgatg
gaagaagtagccagagaagtttttcctcccggctacggatttgcatggtccggccaggca
tttgaagagaaaaaatcgggtgggacttcagctgttgcatttattttcggcatggtaatg
gtctttttgattttggcagctcaatatgaaaggtggtcgatgccatttgctgtgattctg
gctcttcctttcgctttattcggagcgcttttggccatttggctgaggggaatcagtaat
gatgtgtattttcagattggaatggttgcgttgattgcgttggcagccaaaaatgcgatt
ttaattgttgagtttgccatgcagaaatatgaggaggggttttccgcctatgagtcagcg
ttgattgctgccaaacttcgattgaggcctatttgcatgacggcgttttcttttatccta
ggctgcgttcctttggcaatggcaacaggcgcctctgccaacagccgccacagcatcgga
accggggtgattggaggaatgctgggagcaaccgtcatcgcgattttctttattccgttg
ttctatttgttattgcagaagatcagcggtgatcataaggagaagtcggatgaggagtaa

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