Xenopus laevis (African clawed frog): 100049757
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Entry
100049757 CDS
T01010
Symbol
srd5a1.S, srd5a1, SRD5alpha1
Name
(RefSeq) steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) S homeolog
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00140
Steroid hormone biosynthesis
xla01100
Metabolic pathways
Module
xla_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
xla_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100049757 (srd5a1.S)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100049757 (srd5a1.S)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
100049757
NCBI-ProteinID:
NP_001092166
Xenbase:
XB-GENE-6253938
UniProt:
A5D8N5
A0A974CK87
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Position
6S:63645171..63649613
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AA seq
257 aa
AA seq
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MSLSELVGDERQFLNLLAMFMALMGLVSYAMLQYIRMPYGRYATSVFGPPVPVRLAWFVQ
EVPSLFIPVFFYLRQSELGIANQVLMGALICHYIQRTLVFPFLIRGGKPTPFASFALAFI
FCCYNGYMQSSYLCHYAFYASDWIHDPCFITGIMLFFCGMFINIYSDRILRNLRKPGETG
YKIPTGGLFDYVSGANFFGEILEWSGFALAGWSLPAAAFAIFTAFVLTSRAQQHHKWYLE
KFEDYPKNRKILVPFLY
NT seq
774 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctatccgaactagttggagatgaacggcagtttctgaacctcttggctatgttt
atggcccttatgggcctggtgtcctatgccatgctgcagtatatccgaatgccttacggt
cgctatgccacctcggtgttcgggccgccagtaccagtgcgtttggcttggtttgtccag
gaagtgccgtcgttgttcattcccgtatttttttatttaagacaatccgagttaggcatc
gctaatcaggtgctgatgggagccttaatctgtcactacattcaaaggactcttgtattt
ccattcttaatcagaggggggaagcctactccatttgcgtcatttgcacttgccttcatc
ttttgctgttacaatggttacatgcagagcagttatctgtgccattatgctttctatgcc
tcagactggattcatgacccttgttttataacaggcataatgctgtttttctgtggcatg
ttcatcaacatctattctgatcgcattttaaggaatttacgtaaacctggtgaaactgga
tacaaaattcccacgggtggattgtttgattatgtatcaggagcaaacttttttggcgaa
atacttgaatggtctggatttgcgttagctgggtggtcacttcctgctgctgcatttgca
atctttacagcatttgtcctcacttccagagcgcaacagcatcataaatggtaccttgag
aaatttgaagactatccaaaaaacagaaaaatacttgtaccatttttatattaa
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