Xenopus laevis (African clawed frog): 108702762
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Entry
108702762 CDS
T01010
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04120
Ubiquitin mediated proteolysis
xla04144
Endocytosis
xla04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
108702762
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
108702762
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
108702762
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
xla04131
]
108702762
04121 Ubiquitin system [BR:
xla04121
]
108702762
Enzymes [BR:
xla01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
108702762
Membrane trafficking [BR:
xla04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
108702762
Ubiquitin system [BR:
xla04121
]
Ubiquitin ligases (E3)
HECT type E3
108702762
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
WW_TCERG1
Motif
Other DBs
NCBI-GeneID:
108702762
NCBI-ProteinID:
XP_018093909
UniProt:
A0A1L8EMM1
A0A974H0T5
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Position
9_10S:complement(35832076..35875297)
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AA seq
848 aa
AA seq
DB search
MDGSSSRSGAVNGFTMKSQLQVIVISAKLKDNRKNWFGPSPYVELSVDGQSKKTETKNKT
HSPKWKQPLTVIVTPFSVLNFRVWSHQTLKSDALIGSASLNLHETLLSNHMKLEEVIVNM
QLLSDRETVGDLSVCLDGMQVDPELLANGDPAISSGSTDNSAMQIETQSASADTTNGTNS
TDSRTTNGTSSPSLANGGFRASRPSRPPPPTPRRASDIAPAITETSSQAEAELLPPPAAA
ASIPEAPSNTPPVSRQIAPINIDGQRLGLVNQGPLPPGWEQRVDQQGRVYYVDHVAKRTT
WDRPEPLPPGWERRVDNMSRIYYVDHITRTTTWQRPTLESVRNYEQWQIQRNQLQGAMQQ
FNQRFIYGNQDSVAQNKEYDPLGPLPVGWEKRMDGNGRVYFVNHTIRTTQWEDPRNQGQL
NDKPLPEGWEMRFTVDGIPYFVDHNRKTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYF
RFWCQQLYMPQHVKITVNRKTLFEDSFQQIMSFNPQDLRRRLWLIIPGEEGLDYGGVARE
WFFLLSHEVMNPMYCLFEYAGKDNYCLQINPASYINPDHLRYFRFIGRFIAMALFHGKFI
DTGFSLPFYKRILNKPVGLKDLESVDPEFYNSLIWIKDNNIEECGLEMFFSVDKEILGEV
KSHDLKPDGSNIQVTEENKEEYIRLVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDA
KELEVLLCGMQEIDLNDWQRNTIYRHYTRTSKLIIWFWQFVKEIDNEKRMRLLQFVTGTC
RLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIE
ETEGFGQE
NT seq
2547 nt
NT seq
+upstream
nt +downstream
nt
atggatggcagcagttcaagatcaggagcagtcaatggcttcactatgaaatcacagctt
caggttatagttatatccgctaagttaaaggacaaccggaaaaactggtttggtccgagt
ccatatgtggagctatcagtggatggacaatcaaagaaaacagaaacaaaaaataaaact
cacagtcccaaatggaaacagccgctcactgtcattgtaaccccatttagtgtgttaaat
ttccgtgtttggagccaccagacattgaaatctgatgctctgattggaagtgcatcactc
aacttgcatgaaacgctactgtctaaccatatgaaattagaagaagtcattgtgaacatg
cagctgttaagtgacagggagacggtcggcgacctgtctgtgtgcttggatgggatgcag
gtagacccagagctcttagcaaatggagatccagcaatctcatcaggttcaacagataat
tctgcaatgcaaattgaaacacagtctgcaagtgctgacaccacaaatggaacaaattca
actgacagcagaacaaccaatggcacaagctctccttctttagccaatggaggcttcaga
gccagtagaccatcacggccccctccacccacacctcgccgggcgtctgatatagctcct
gccatcactgaaacttcctcccaagctgaagctgaattgttgcccccccctgctgctgct
gcttccatacccgaagctccatccaacacacctcctgtttctaggcaaatagctcccatc
aacattgatggacagagactgggactagtgaaccaaggacctctgccacctggatgggaa
cagcgggttgatcagcaaggacgtgtttattatgtggatcacgttgcaaaaagaacaaca
tgggacaggccggaacctctacctcctggatgggaacgtcgagtggacaacatgagtcgc
atctattatgtggatcatataaccaggaccactacatggcagcgccccactttggaatct
gtgagaaattatgagcagtggcaaatccagcgtaaccagctgcaaggggccatgcaacag
tttaaccaaaggttcatttatgggaaccaggattccgtagcccagaacaaagagtatgac
ccattaggaccattaccggttggatgggaaaagcggatggatggaaatggcagagtatat
ttcgttaatcacacaattcggaccacccagtgggaggacccaagaaatcagggacagttg
aacgacaagcctttaccagagggttgggaaatgaggtttacagtagacggcatcccatat
tttgtggatcacaacaggaaaaccaccacctatattgatcctcggactggcaaatcagct
ctggacaatggacctcaaatcgcctacgtaagggattttaaggctaaggttcagtacttc
cgattttggtgccagcaactttatatgcctcagcatgtcaagatcactgtgaacaggaaa
acgctttttgaagattcatttcagcaaataatgagtttcaacccacaagatctcaggaga
agactgtggcttatcatccctggggaagagggtttagattatggaggagtggcaagagag
tggttcttcctcctgtcccatgaagtaatgaatccaatgtactgcctatttgaatacgct
gggaaggataactactgtctacagatcaaccctgcttcctacattaacccagaccacctc
cgctacttccgcttcattggcaggttcatagccatggccctgttccatggcaagtttata
gacacgggtttctcgttgcctttttacaaacggatcttaaataaaccagtgggtctaaaa
gatttggaatctgtggatcctgaattctacaattcacttatatggataaaggacaacaac
attgaggagtgtggcctggagatgtttttttcagtggacaaagaaattttgggggaagtc
aaaagtcatgatctgaaacctgatggcagtaacatccaggtgacggaagagaacaaggaa
gaatacatccggctagttgcagagtggagactgtcccggggagtagaagaacagacacag
gctttctttgagggtttcaatgagattctccctcaacaatacttgcaatattttgatgca
aaggagttagaggtgcttctgtgtggaatgcaggaaattgatctaaatgattggcagcga
aacaccatctacaggcactacacaaggaccagcaagctcatcatttggttctggcagttt
gtaaaagaaattgataatgagaagcgaatgagacttctgcagtttgtgaccggcacctgc
aggttacctgttggaggatttgctgatctaatgggaagcaacgggcctcagaaattctgt
attgagaaggttggcaaagaaaactggcttcccaggagtcatacgtgctttaaccgtctg
gatcttccaccctacaaaagctacgaacagctgaaagaaaaactactgtttgctatagag
gagacagaaggtttcggacaggaataa
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