Xenopus laevis (African clawed frog): 108714143
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Entry
108714143 CDS
T01010
Symbol
mlkl.L
Name
(RefSeq) mixed lineage kinase domain-like protein
KO
K08849
mixed lineage kinase domain-like [EC:
2.7.11.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04217
Necroptosis
xla04623
Cytosolic DNA-sensing pathway
xla05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
108714143 (mlkl.L)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
108714143 (mlkl.L)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
108714143 (mlkl.L)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
108714143 (mlkl.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
108714143 (mlkl.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: TKL group
Other
108714143 (mlkl.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MLKL_N
Pkinase
DUF7792
Baculo_PEP_C
DUF5798
RPW8
DUF1664
MCPsignal
FRB_dom
Syntaxin
DUF7118
Med9
Motif
Other DBs
NCBI-GeneID:
108714143
NCBI-ProteinID:
XP_018113556
Xenbase:
XB-GENE-17335660
UniProt:
A0A1L8GLD7
A0A974D2Y6
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All DBs
Position
4L:69097638..69119316
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AA seq
496 aa
AA seq
DB search
MEILGNVLDIAQTIYGLCDQASSNKRQCSRLRKRIEILLVAATKIKKQPEKSSELKVVLR
ELQLTLRNAKSWVLKYSNQGWWMKILKANCIKEEFDLINDRLKDAADDISVLLAIEHRES
FLKFFDENKRLKQSQKDIEEDMSELKERLNSGVGSLTKDISHVAETVEDTNSGVKNILNQ
VEEIKSLLSSGTRTPRLCTEIKSEDLIWGALVMEKPNFDLYRGQYYKSPVAIKVLKGQPL
ENVEKIREIFNLEIKTMKKYECVNIIRVFGICIDKAKSEPYYCMVTEFCEKGTLRELLSR
EKNLPWNRRIHMTLDAARALYRLHQTETKPMLHGSLSSSKFLVDGTYCLKLSGFELSKTE
SSMRRQPNVEKQKQNIEWSYIAPETMQNINAYDKHSEIYSLGIVFYEIATGRIPIQGLSG
TNPNDMYQNLSKDMKEGLPADCPSVLSDLIVQSTGTNPTERPSAGVIVDLLMDYLNQQEA
SEAAALIGNMGFTEEN
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atggaaattctggggaatgtcttggacatagcacaaactatctatggtctgtgtgatcag
gccagttccaacaaaaggcaatgttctcgtctgaggaaaagaattgaaatcttgctggtg
gctgctactaagatcaagaaacagccagagaagtccagtgagcttaaggttgttttgagg
gagctgcagctcactttgaggaatgccaagtcctgggttcttaaatattccaatcagggg
tggtggatgaaaatcctcaaagctaactgtataaaggaagagtttgatctaataaatgat
cgccttaaggatgctgctgatgacatctctgtactgcttgctatagaacatcgggaaagc
tttctcaaattttttgatgaaaacaaaaggctaaaacagagccagaaagacatcgaagaa
gacatgagtgaactaaaagaacgcctcaatagtggtgttgggagtctgactaaggacatc
agtcatgtggcggaaacggtggaagatacaaattctggagtaaagaacatactcaatcaa
gttgaagaaataaagtccttgttatcttcaggaacaagaactccacggctttgcacagag
ataaagtctgaggatctgatatggggagctcttgtgatggagaagcctaactttgacctg
tatagaggacagtactataagagtccagtggctataaaggttttgaagggacagcccttg
gaaaatgttgaaaaaatcagagaaatatttaatttggagataaagacaatgaaaaaatat
gaatgcgtgaatattatacgtgtatttggcatatgtatagacaaagcaaagagtgagcct
tactactgtatggtgactgagttctgtgaaaaggggactctcagagagctgctgagcaga
gagaagaacctcccctggaatcggcgtattcacatgacattggatgctgcaagagcattg
tacaggttacaccagacagagacaaaacctatgcttcatgggagcctgagcagttcaaag
ttcttggtagatggcacttattgccttaagctatctggatttgaactatcaaagacagag
tcctccatgagaagacaacctaatgttgagaagcaaaaacaaaacatagaatggtcgtac
attgcccctgaaacaatgcagaatatcaacgcttacgataaacatagtgagatttacagc
ctgggaattgtgttttatgaaattgcaactggcaggattccaatacagggtctttccggc
acaaacccaaatgacatgtaccaaaatctaagtaaagatatgaaagaaggtctgcctgct
gactgcccatctgtcctgtctgatctaattgtacaaagcacaggaactaatcccactgaa
cgaccctcagctggagttattgtggatttactcatggactatttaaaccaacaagaggcc
agtgaggctgctgcattgatcggcaatatgggtttcactgaagaaaattga
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