KEGG   Xenopus laevis (African clawed frog): 108716652
Entry
108716652         CDS       T01010                                 
Symbol
mtr.L
Name
(RefSeq) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00270  Cysteine and methionine metabolism
xla00450  Selenocompound metabolism
xla00670  One carbon pool by folate
xla01100  Metabolic pathways
xla01230  Biosynthesis of amino acids
xla04980  Cobalamin transport and metabolism
xla04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    108716652 (mtr.L)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    108716652 (mtr.L)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    108716652 (mtr.L)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    108716652 (mtr.L)
   04980 Cobalamin transport and metabolism
    108716652 (mtr.L)
Enzymes [BR:xla01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     108716652 (mtr.L)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding MtrH CdhD
Other DBs
NCBI-GeneID: 108716652
NCBI-ProteinID: XP_018118431
Xenbase: XB-GENE-6488723
UniProt: A0A1L8G7P5 A0A974HJ81
LinkDB
Position
5L:41930602..41976996
AA seq 1266 aa
MPPTIQHAEPSGVRKRNLQEELDSVLRQRIMVLDGGMGTMIQQHTLGEESFRGQEFIDHA
KSLKGNNDLLSITQSEIIYKIHKEYLTCGADIVETNTFSSTSIAQADYGLEHLAYRLNKV
SAEVARRAADDVTAETGVKRYVAGAMGPTNKTLSVSPSVERPDYRNVTFDELVDAYAEQA
RGLLDGGVDILMVETIFDTANAKAALYAIQKLFEEDYEPRPIFISGTIVDKSGRTLSGQT
GEAFVISLSHAEPLCIGLNCALGAIEMRPFIEAIGKCTTSYVICYPNAGLPNTFGGYDET
PEVTAKHIKDFALDGLVNIVGGCCGTTPAHIREISEAVKNCKPRIPPTSVFDGYMLLSGL
EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMSGNYEEALSVAKAQVEMGAQILDINVDDG
MLDGPTAMARFCNYVASEPDIAKVPLCIDSSNFEVIEAGLKCCQGKCIVNSISLKEGEED
YLAKAKKIKQFGGAVVIMAFDEVGQATDTETKVSVCTRAYNLLVEKLNFNPNDIIFDPNI
LTIGTGMEEHDKYAIHFIEATKMIKESLKGARVSGGLSNLSFSFRGMEAIRESMHGVFLY
HAIKAGMDMGIVNAGNLPVYDDIDKELLNLCEDLIWNRDPDGTEKLLKYAQTKAKGGKKV
IQTDEWRTGSVEERLEYALVKGIEKYVIEDTEEAKANKEKYPRPLHIIEGPLMNGMKVVG
ELFGAGKMFLPQVIKSARVMKKSVGFLIPFMEKEREEMRAISGSLEEDNPYQGTIVLATV
KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILRAAIENKADIIGLSGLITPSLDEM
IFVAKEMERLGIRTPLLIGGATTSRTHTAVKIAPRYSAPVIHCLDASKSVVVCSQLLDEN
VRDEFIEEVSEEYEDIRQDHYDSLKERRYLSLEQARNKGLHIDWLSHSKPVRPKLIGTEV
YKDYDLEKLRHYIDWKPFFDVWQLRGKYPNRAFPKLFNDKTVGEEAKRVYEDAQKMLNTI
ISEKKFEARGVVGIWPAHSVQDDILLYAEEGNMNSAEAIATFYGLRQQAEKDSASTDPYY
CLSDFIAPKNSGVQDYLGIFAVSCFGVEELSKVYEKQGDDYSSIMTKALGDRLVEAFAEE
LHERVRKDLWGYCSEEQLDVSDLRRICYEGIRPAPGYPSQPDHLEKVTMWKLADVERTTG
IKLTESLAMSPAASVSGLMFSSPMSKYFAVGKISKDQVEDYACRKNVPLSEAERWLGPIL
SYDLED
NT seq 3801 nt   +upstreamnt  +downstreamnt
atgccccccactatccaacatgctgagccttcaggtgttaggaagaggaacctgcaggaa
gagttggactcagttcttcgtcagagaatcatggttttggatggtggcatgggcaccatg
atccagcaacataccctgggggaggaaagtttcagagggcaggagtttatagaccatgct
aaatcattaaaggggaacaatgacctgctaagtatcacacagtcggaaataatatacaag
attcacaaggaatatttgacttgtggagccgatattgtggaaacgaacacatttagcagc
actagcattgcacaggcagactatggccttgagcacctggcataccgtttgaacaaagtt
tcggcagaggtagccaggcgagcagcagatgatgtgacagctgaaacaggcgtaaagagg
tatgttgctggagctatgggtccaacaaacaagaccctgtctgtgtctccttcagtagaa
agaccagattatcggaatgttacttttgatgaacttgtggatgcctatgcagagcaggca
aggggacttctggatggtggtgtagacattttgatggtagaaacaatattcgatacagct
aatgcaaaggctgctctctatgctatccagaaactatttgaagaagactatgaaccaaga
cctatctttatttcagggaccattgtagataaaagtggccgaacactctctggacaaact
ggagaagcctttgtaataagcttgtcccacgctgagccgctttgcattgggttaaactgc
gctttgggagctatcgaaatgagaccttttattgaagccattgggaaatgcacaacatcc
tatgtcatctgttatccaaatgcaggtcttcccaacacatttggtggctatgatgaaaca
cctgaagtcacagctaaacatataaaggattttgcactggatggtttggtgaatattgtt
ggtggctgctgcggaactacaccggctcacatcagagagatttcagaagccgttaagaac
tgtaaaccacgaattccccctacatcagtatttgatggttatatgctactctcgggttta
gagccctttaggattggaccgtatacaaatttcgtcaatataggagagcgctgtaatgta
gctgggtcgagaaagttcgccaagctaatcatgtcaggcaattatgaggaggctctgtct
gttgccaaggctcaagtggagatgggagctcagattctggatattaatgtggatgatgga
atgctggacggcccaactgcaatggccagattttgtaattatgtagcctcagagccagac
atagccaaggtacccttgtgcattgactcctccaattttgaagtcatagaggctggattg
aaatgctgtcagggaaaatgcattgtaaacagcatcagtctgaaggaaggagaggaagac
taccttgcaaaggccaaaaaaattaagcagtttggtggtgctgtggtgatcatggctttt
gatgaagtggggcaggccacagacacggagactaaagtcagtgtgtgtacaagagcttat
aacctgctggtcgagaagttgaatttcaaccccaatgacatcatctttgacccaaacatc
ctaacaattggcactggcatggaagaacatgataaatatgctattcattttattgaagcc
accaaaatgattaaggaatctttaaaaggtgctagagtaagcgggggcctctccaatctt
tctttttcattccgtggaatggaagccatcagagaatccatgcatggagtctttctgtac
catgccataaaggctggcatggatatgggaatagtgaacgctgggaaccttccagtttat
gatgatattgacaaagagctcctcaatctgtgtgaagatctaatctggaacagagatcct
gatggaacagagaagctcttaaaatatgctcagacaaaggctaaaggtggtaagaaagtg
atccagactgatgagtggagaactggctctgtagaagagaggttggaatatgcacttgtc
aagggcattgaaaagtatgttattgaagatactgaggaagcaaaagcaaacaaggagaaa
tatccaagacctctgcacatcattgaaggacctcttatgaatggcatgaaagtagttgga
gagctctttggtgcagggaagatgtttttgcctcaggtaattaagtctgctcgagtgatg
aagaagtctgtgggatttctgattcccttcatggagaaagaaagggaggagatgagagcc
atatctggcagtctggaagaagataatccctatcaaggcacaattgtactggcgacagtt
aaaggggatgtgcatgacattggcaagaatattgtaggagtagtgctggggtgcaataac
ttcagggtaattgatctaggtgtcatgactccatgtgacaagatactacgagctgcaata
gaaaacaaagcagatataattggtttgtccggtcttatcactccttctctggatgaaatg
atttttgttgccaaggagatggaaaggcttggtataagaacccctctgctaattggtgga
gcaacaacatcccggactcacactgctgtgaaaatagcaccacgatacagcgccccagtt
atccactgtttagatgcttcgaagagcgtggttgtttgctctcagcttcttgatgaaaat
gtcagagatgaattcatagaagaagtatcagaagaatatgaagatattcgccaagatcac
tacgactccctcaaggagagaagatatttgagtttagaacaagccagaaataaaggactg
cacattgattggctttctcactcaaagccagtgcgacccaagttgattggaacagaggtt
tacaaggactatgatcttgagaagctgcgtcactatattgactggaaacctttctttgat
gtgtggcagcttaggggcaaatacccaaacagagcatttcccaaattatttaatgataag
actgtgggagaggaagcaaagagagtctatgaagatgcccagaaaatgctgaatacgatt
attagtgaaaagaagtttgaggccaggggtgttgttggtatctggccagctcacagtgta
caagatgatattctgttatatgcagaagaagggaatatgaattccgcagaagccattgca
acattttatggcttacgacagcaggcagagaaagactctgcatccactgacccatattac
tgcctatctgacttcatcgcccctaagaattctggggttcaagactatttgggaattttt
gctgtgtcatgttttggggtggaagaactgagcaaagtgtatgagaaacaaggagatgac
tacagcagcatcatgaccaaagccctgggagataggctggttgaggcctttgcagaggag
cttcatgaaagagtcaggaaagacctgtggggctactgtagtgaggagcaactggacgtg
tctgacttgcgcaggatatgctatgaaggcatccgaccagctcctggataccctagccaa
ccagatcacttggaaaaagttaccatgtggaaactagcagatgttgaaagaacaacagga
attaagctgacagagtctctagccatgtctcccgctgcttcagtctctggactgatgttc
tctagtcctatgtccaagtattttgctgtagggaaaatttccaaagatcaggtagaagat
tatgcttgcagaaaaaatgtgccattgagtgaagctgagagatggttgggcccaattctg
agctatgatctggaagactag

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