Xenopus laevis (African clawed frog): 399391 Help Entry 399391            CDS       T01010                                  Symbol brca1.L, brca1 Name (RefSeq) breast cancer 1 L homeolog   KO K10605   breast cancer type 1 susceptibility protein [EC:2.3.2.27] Organism xla  Xenopus laevis (African clawed frog) Pathway xla03440   Homologous recombination xla03460   Fanconi anemia pathway xla04120   Ubiquitin mediated proteolysis Brite KEGG Orthology (KO) [BR:xla00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     399391 (brca1.L)   09124 Replication and repair    03440 Homologous recombination     399391 (brca1.L)    03460 Fanconi anemia pathway     399391 (brca1.L)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:xla01009]     399391 (brca1.L)   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:xla04121]     399391 (brca1.L)    03036 Chromosome and associated proteins [BR:xla03036]     399391 (brca1.L)    03400 DNA repair and recombination proteins [BR:xla03400]     399391 (brca1.L) Enzymes [BR:xla01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      399391 (brca1.L) Protein phosphatases and associated proteins [BR:xla01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      399391 (brca1.L) Ubiquitin system [BR:xla04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    Other single Ring-finger type E3     399391 (brca1.L)   Multi subunit type E3    BRCC complex     399391 (brca1.L) Chromosome and associated proteins [BR:xla03036]  Eukaryotic type   Centrosome formation proteins    Centrosome duplication proteins     Regulators of centriole replication      399391 (brca1.L) DNA repair and recombination proteins [BR:xla03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     BRCA1-core complex      399391 (brca1.L)     BRCA1-A complex      399391 (brca1.L)     BRCA1-B complex      399391 (brca1.L)     BRCA1-C complex      399391 (brca1.L)     BRCA complex      399391 (brca1.L)    FA (Fanconi anemia) pathway     Downstream FA components      399391 (brca1.L) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  BRCT zf-C3HC4 zf-RING_UBOX zf-C3HC4_2 zf-C3HC4_4 zf-RING_2 BRCT_2 RING_XB3-XBAT31 zf-C3HC4_3 zf-Nse zf-RING_5 BRCT_3 zf-RING_6 zf-RING_10 zf-MIZ zf-rbx1 TRAF3_RING Motif Other DBs NCBI-GeneID:  399391 NCBI-ProteinID:  NP_001084248 Xenbase:  XB-GENE-6254021 UniProt:  Q90X96 LinkDB All DBs Position 9_10L:complement(34996121..35051771) Genome browser AA seq 1579 aa AA seqDB search MTCSRMDIEGICSVISVMQKNLECPICLELMKEPVATKCDHIFCKFCMLQLLSKKKKGTV PCPLCKTEVTRRSLQESHRFKLLVEGQLKIIKAFEFDSGYKFFPSQEHTKGLDSTIEDVL VKEDQSIVHCKGYRNRKKGVFNRKTYEETGMLSVSKAEEQFAKEVTRLIPCRQKKPKKEA ALIFSNCVPDSSDGDLLNKENGLRNDCSPLHYEKEDTQIPEMEEMVESDLAECEFAESAG SNLLGFDGPEGIPEISAETSINAAGNCDFYGRKTEQFPNDHHCSFKQNIADAEQNKRNQH CGNVPFAPMGKSNLDEKETVETDFDNQHNDSNPENNDPLGKVTKLMRRSTERVNEWLLKT NQDFSTLSAEEDPILDALALQNKETSDKRSCSSDDSELMPVLHKHAEKGISGGGFDKPAV GVKDKIFCKVYKRERKAMPPNNITCVAEVHHDSALETGKENMTLEYGTGMSHLMSKRKMV YSLNPENTSKKNDLANINGSINVFPDCISDANLELEDKSEADSNSADACQSDIVHSSNTQ IKQQCVESLANAGETRKKQELSCERSQEEKDFTQSGALGPKTRSQKSPYGHSELHIESSQ ISNEPSNVTKQVEVRRSRRLLMLPKGPGNKSNSNAVKEMNEQENIAQIPEFRVKDTNKNN EISDTVPSQLKKKDTYFPPCTSEDTGELENGIPVRKISDQNASLDNPIDPCKDEYSDTLL HVAGDNVQPDYMETEESELETQHIVKMFKTSKRTSFILESKEAENENRVNSAVEISQVET SNELPNVAECRHTSLLSSAKEQSGALLKQGSPSSEPKKTSPIHMLKKTESKHSKMSRNRR GKVKPSSNSAKNTTGQPDNLNNPTQGVTGSLYNKQVMSDFPMRLNVDEEHTNASAKGSQS SVADKSTAHSNVNTDFISDINSATPDGLLHYMDKAEGNSSPWDTTRDKNAALLESCLPSA YGSTGEKTPIPKVQSSEEGSSQGLFNQKPKCSSSGKADQKNSSKNPGKSQCRILSDFSGS SNNGKCSSQEMLSKAAFPSLSQESQCSVSLFSTQSNMSQQSVDEDHKQDVLQDELVSPNK TKRTAISGTEETQISPLRDQYQNPDIDEASECESEASHTGDSSILSSQDELLNTQQRNYM KDSLKKLQQEMAALEAVLGQHGTQKLEAETTCIPSSEHVTEMQEATEEEEEETYQGENLF VKTPPEHVANGSTLIGQSTDNGLQGRNRPVSPSFLCQTRIEKDTPEIVCPAMGISKKSLL TQKELPSQHKQEIRPDLETVNVTPTNPIDAQESLRQSSKNKRGSRMLHNKRSTSNQGSFC LSVEAAESPQIPKQNKAEFGIARKSTSPTFASPARAKVPSVGFKSPVVSSRRNLSFVASG LNQCEMALVQRFSKTTQSILSSRITDSTTHVIMKTDAELVCERTLKYFQGIASRKWVVSY EWVVQSFREGQILDEYDFEVKGDVINGRNHRGPRRSRLGSDGLLLIDFEICFFGSFTDMT LDDLEWMVSECGATVVKKLQFFKKKHNVTSLVIVQPDASTEVRDYTEIRKKHKALVVTRE WLMDSVATYRLQKFDAYLA NT seq 4740 nt NT seq  +upstreamnt  +downstreamnt atgacctgctcaagaatggatattgaaggcatttgtagcgtgatttcggtcatgcagaag aatttggagtgcccaatctgcttagagctgatgaaggaaccagttgcaacaaagtgtgat cacatattttgcaaattttgtatgctacaacttctcagcaaaaagaagaaaggaactgtt ccgtgccctttatgcaagaccgaagtaactagaaggagtcttcaggaaagtcaccgattc aaacttctggttgaagggcagctgaagattataaaagcctttgagtttgactcgggatac aaattctttccaagtcaagaacacacaaaggggttggattccacaatcgaggatgtcttg gtgaaggaagatcagtccatagtgcactgcaaaggttacagaaaccgtaaaaaaggcgtc ttcaacagaaaaacgtatgaagaaactggaatgttatcggtatccaaagccgaagagcaa tttgctaaagaagttacaagactgattccttgcagacagaagaaacctaagaaagaggct gcactcattttcagtaattgtgttcctgattcttctgatggtgatttattgaataaagaa aatggcttgagaaatgactgctctccactccactatgaaaaagaagacacacaaattcca gagatggaagaaatggtggaatcggacctagctgaatgtgaatttgctgaaagtgcagga agcaatttattgggttttgacggtcctgaaggcattcctgaaatatcagcagaaacaagt atcaatgcagctggtaattgtgacttttatggaagaaaaacagagcagttccctaatgac catcattgcagcttcaagcaaaatattgcagatgcagagcaaaacaaaagaaatcagcat tgcggcaatgttccttttgcaccaatggggaaatccaatttagatgaaaaggaaaccgta gaaactgactttgataaccagcataatgactcaaaccctgagaataatgaccctttaggc aaagtcactaaattaatgagaaggagcacagaacgggtcaatgagtggttgctaaaaaca aatcaggatttcagcactttgtcagcagaggaagaccctatccttgatgcattagctttg caaaataaagagacctctgacaaaagatcttgctcctcagatgactctgaattaatgcct gtacttcataaacatgctgagaagggtatatcaggtggtggttttgacaaaccagcagtt ggcgtaaaggacaaaatattctgtaaagtctacaagagagagagaaaagctatgcctcca aataatataacctgtgtagctgaggtccatcatgatagtgctttagagactggcaaagaa aatatgactctggaatatggcacaggaatgagtcatttaatgtccaaacggaaaatggtc tacagtctaaatcctgaaaacacttccaagaagaatgacctagctaacataaatggaagc attaatgtttttcctgactgtatatctgatgccaatttagagctggaggataaatcagag gctgactctaattctgctgatgcatgtcagtctgacatagttcattccagtaatactcaa attaaacaacagtgtgtggaatctttggcaaatgcaggtgaaaccagaaaaaagcaagag ttatcttgtgaacgaagccaagaggaaaaagactttactcagtctggtgcattaggacct aaaacacgctcacagaaaagtccttacgggcactcggagctacatatagaaagttctcaa attagtaatgagccaagtaatgtaacaaagcaggtggaagtgagacgaagcagaaggctt ttgatgttgccaaaaggaccaggaaacaaatcaaattcgaatgcagttaaggaaatgaat gaacaggagaatattgctcagattccagaatttcgggtgaaagacacaaataaaaacaat gagatttctgatacagttccttcacaacttaaaaagaaagacacatacttcccaccttgc acttctgaagatactggtgaattggagaatgggattcctgtgagaaaaatcagtgatcag aatgcctctttagataatcctatagacccctgtaaggatgaatattcggacaccttgcta catgttgcaggggataatgtgcagcctgattacatggaaactgaagagtcggaactggaa acccaacacatagtaaaaatgtttaaaacttctaagcggacatccttcatattagagtcc aaggaagcagaaaatgagaatagggtaaactctgctgtggagatttcgcaggtcgaaact tctaatgagttgcctaatgttgctgaatgcaggcacacttctctgttaagttcagctaaa gaacaaagtggtgcattgctgaaacagggcagccccagtagtgagcctaaaaaaaccagc ccaatacacatgctcaaaaaaactgaatcaaaacatagcaaaatgtcccgcaacagaaga gggaaagttaaacccagttctaattctgctaaaaatactactggccagccagacaattta aacaaccccacccagggggtcactggtagcctatataataaacaagtaatgagtgatttt cctatgaggctcaatgttgatgaagaacatacaaatgcatcagctaaaggtagccaaagt tcagtggctgataaatccacagcacattctaatgtcaatactgacttcatatctgatatt aattctgccactcctgatggattgttgcattacatggataaggctgaaggaaattcaagc ccatgggatacaaccagagacaaaaatgcagctctccttgagagttgtcttccttctgcc tatggatcaacaggggaaaaaactcctataccaaaggtacaatcatcagaggaaggatca tctcagggtctatttaatcaaaagccaaagtgctcatcctccggtaaagcagatcagaag aattcttctaaaaatccaggtaaatctcagtgtaggatcttgtcagatttcagcggcagc agcaataacggaaaatgcagttcacaggagatgctgtcaaaggcagcctttccttctctg agtcaagaatcgcagtgttccgtgagcttgttctccacacagtcaaatatgtctcagcaa tctgtagatgaagaccacaaacaagatgtgctccaggatgaactagtcagtccaaataaa accaaacggacagccatcagtggtacagaagagacacagatttctccccttcgggaccag tatcagaatcctgatatagatgaagcatcagaatgtgagagtgaagcaagtcatacagga gattcctctatattgtcttcacaggatgaactcctgaacacccagcaacggaattacatg aaggacagtttaaagaaactgcagcaagagatggctgcattggaagcagtactggggcag catgggacccagaaacttgaagcagagacaacatgcatcccttcatctgagcatgtcaca gaaatgcaggaggctactgaagaagaagaagaggagacatatcaaggagagaacttattt gtaaaaacccctccagagcatgttgcaaatgggtcaactttgataggccagagcactgac aatggattgcagggcaggaatcggccagtgtctccatcttttctatgccagaccaggatt gagaaggatactccagaaatagtatgcccagcaatgggcatatcaaaaaaatctttgctt acacagaaagaacttccaagccagcataaacaggaaatcagacctgatcttgagacagtt aatgtgacaccgaccaacccaatagatgcccaagaatctttgaggcaaagcagcaagaac aagagagggagccgtatgttgcacaataaacgttccacatctaaccaaggctcgttttgt ctttctgtggaagctgcagagtctccacaaatccccaaacaaaacaaagcagagttcggc atcgcaaggaaatccacctcacctacttttgcgtctccggctcgagccaaagtaccttct gttggttttaagtctcctgtggtgtcatcaaggaggaatctgtcctttgtggcttctggg ttaaatcaatgtgagatggcattagtgcaacgattttcaaaaacaacccagagcatttta tccagtcgaattactgattcaacaactcatgtcatcatgaaaacagatgcagagcttgtg tgtgaacgaactctaaagtatttccaaggaattgccagtcgaaaatgggtggtaagctat gaatgggttgtacagtcattcagagaggggcaaatccttgatgagtatgactttgaagtg aagggagatgtgatcaatggaagaaatcatagaggtcccagacgatcaaggctgggatcc gatggattgctgctaatcgattttgaaatttgcttctttggctcattcactgacatgaca ctcgatgatcttgagtggatggtgtctgagtgtggagccactgtggtgaaaaaacttcag ttctttaaaaagaaacacaatgtgacatcgcttgtgattgtgcaacctgatgctagtacg gaagtccgagattatactgagatcaggaagaagcacaaggcactagtagtgacgcgtgag tggttaatggacagtgttgctacttacagacttcagaagtttgatgcttaccttgcataa

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