Xenopus laevis (African clawed frog): 734717
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Entry
734717 CDS
T01010
Symbol
hsd17b7.S
Name
(RefSeq) 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
KO
K13373
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:
1.1.1.62
1.1.1.270
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00100
Steroid biosynthesis
xla00140
Steroid hormone biosynthesis
xla01100
Metabolic pathways
Module
xla_M00101
Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
734717 (hsd17b7.S)
00140 Steroid hormone biosynthesis
734717 (hsd17b7.S)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
734717 (hsd17b7.S)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
734717 (hsd17b7.S)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
SDR
Epimerase
NAD_binding_10
2TM
Motif
Other DBs
NCBI-GeneID:
734717
NCBI-ProteinID:
XP_041417548
Xenbase:
XB-GENE-976830
UniProt:
Q498H1
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Position
4S:98115737..98126804
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AA seq
329 aa
AA seq
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MRKVVVVTGANSGIGLALCERLLSNDDQIRLCLACRNLQRAEAARSALLSSHPSADVGVL
LVDVGKVKSVVQAAKELKERYKKVDYLYLNAGIMPNPQISLRAFINGLFSRNVINMFATA
EGILTQKDRVTEDGLQEVFETNVFGHFMLIREIEPLLCQGDSTSQLIWTSSSNARKSAFS
LSDYQHSQSQEPYSSSKYATDLLSVALNKHYNKQGLYSSVVCPGLVMTNLTYGIMPSFLW
TLIMPIMWLIRIFTNSFTISTYNGAEALMWLFKQKVESLDPLSKYHSCTSGLGNNYVNLT
KMDVEEESGDLLFQKMLELEKEIRKKCIS
NT seq
990 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaggtcgtagttgtcacgggcgctaacagtggcattggcttggcgctctgtgag
cgtcttctttccaatgatgaccaaatccgcctgtgcttagcatgcagaaacttgcaaagg
gcagaggcagcccgctctgctctcttgtcttctcacccgtcggcagatgtcggtgtcctg
ctcgtagatgttggtaaagttaagtctgttgtacaagcagcaaaagagctaaaggaaagg
tataagaaagtggactatttatacttgaatgctggcatcatgccaaatcctcagatcagc
ctcagggccttcatcaatggtttgttttccagaaatgtcatcaatatgtttgcaaccgcc
gagggaattcttacccagaaagacagggttacagaagatggtttgcaggaagtttttgag
accaatgtttttggtcattttatgttgattagagaaattgaaccccttctatgtcaaggg
gacagcacatcacagcttatatggacctcatcaagcaatgcaagaaaatccgcctttagt
ctttcagattatcaacacagtcagagtcaggaaccctacagctcctcaaaatatgcaaca
gacttgttaagtgtggctctcaacaagcactacaacaaacaaggcttgtactccagtgtg
gtatgcccaggccttgtgatgacaaatctaacatacggcatcatgccttctttcttgtgg
acactaatcatgccgataatgtggctgatccggattttcacaaactcttttacaatctca
acgtacaatggagcagaggctttgatgtggctgtttaagcaaaaggtagaatcacttgac
cccctgtccaaatatcacagctgcacatcaggactgggaaataattatgtaaatttaaca
aagatggatgttgaggaggaaagtggtgacttgttatttcagaagatgctggaattagaa
aaggagattcgtaaaaaatgtatctcttga
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