KEGG   Xenopus tropicalis (tropical clawed frog): 100135731
Entry
100135731         CDS       T01011                                 
Symbol
pak1
Name
(RefSeq) serine/threonine-protein kinase PAK 1 isoform X1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04010  MAPK signaling pathway
xtr04012  ErbB signaling pathway
xtr04510  Focal adhesion
xtr04625  C-type lectin receptor signaling pathway
xtr04810  Regulation of actin cytoskeleton
xtr05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100135731 (pak1)
   04012 ErbB signaling pathway
    100135731 (pak1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100135731 (pak1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100135731 (pak1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100135731 (pak1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100135731 (pak1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xtr01001]
    100135731 (pak1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xtr04131]
    100135731 (pak1)
   03036 Chromosome and associated proteins [BR:xtr03036]
    100135731 (pak1)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100135731 (pak1)
Protein kinases [BR:xtr01001]
 Serine/threonine kinases: STE group
  STE20 family
   100135731 (pak1)
Membrane trafficking [BR:xtr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100135731 (pak1)
 Endocytosis
  Macropinocytosis
   Kinases
    100135731 (pak1)
Chromosome and associated proteins [BR:xtr03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     100135731 (pak1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT YrbL-PhoP_reg
Other DBs
NCBI-GeneID: 100135731
NCBI-ProteinID: XP_017947249
Xenbase: XB-GENE-967716
UniProt: F6T2D3
LinkDB
Position
2:171761151..171812220
AA seq 521 aa
MSNNALAIEDKAPPPPIRINSTIGGGNTNKWNEKDKKIKKGEEKSQPFNFPHKGNKKVKN
PPLVISSPFGYEHIYHVGIDPSTGEFTGMPKQWAQLLQTANISKIDQKKNPQVVLDVLNF
YSSETTSKSQKYMSFTDNSREAYNSNSVLDAKPVPEVAEVLPVPEAEDPPAFPPRPDHTK
SIYTRSVIEPPVPPLAAKPTTENGSSVTDGAESSVDKTKKKPKMTDEEILEKLRSIVSVG
DPKKKYTRFEKIGQGASGTVYIAVDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKH
PNIVNYLDSYLVGEELWVVMEYLAGGSLTDVVTETCMQEGEIAAVCRECLQALEFLHSNQ
VIHRDIKSDNILLGMDGAVKLTDFGFCAQISPEQNKRSTMVGTPYWMAPEVVTRKAYGPK
VDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPQLQEPEKKSPAFRDFLSRCLEM
DVEKRGSARDLLQHPFLKVAKPMSSLTPYIITGKQMAKGGL
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccaacaatgccttggcaattgaagacaaggccccacctccacccataaggatcaat
agcacaataggcgggggcaatacgaacaaatggaatgaaaaggacaaaaaaattaaaaag
ggtgaagagaaatcccaacctttcaactttcctcataaaggtaacaaaaaggttaagaat
ccccctctggtgatttccagcccatttggctatgagcatatctatcacgtggggattgat
ccctctacaggagaatttactggcatgccgaaacagtgggcccagcttctgcagactgca
aacatcagtaaaattgatcagaagaagaacccacaggttgttctggacgtactgaatttc
tacagttctgagacaacctccaaaagccaaaagtacatgagcttcacagataactctaga
gaggcttataattccaattcagtcttggatgccaagcctgtgcctgaggtggcagaggtc
cttcctgtgccagaagctgaagatccccctgctttccctccgcgtcctgatcacacaaaa
tcaatatacacacgctctgtcattgagcctccagtcccgccactggcagctaaaccaact
acagagaatggcagttcagtcactgatggagcggaaagcagcgtggacaagacaaagaag
aagcccaagatgacagatgaggagatcttagagaagctgagaagcatagtaagtgttgga
gacccaaagaaaaagtacacacgatttgagaagattggacagggggcgtctgggacagtt
tacattgctgtggacgtggccactggccaagaggtggcgatcaagcagatgaatttgcag
cagcagccaaagaaagagttaattatcaacgagatccttgtaatgagggaaaacaagcat
ccaaacattgtgaattacctggatagttacttggtcggggaggagctgtgggttgtgatg
gaatatctagcggggggatctctcactgatgttgtaacagagacctgtatgcaagagggc
gagatcgcagctgtgtgcagagagtgtcttcaggctctggaatttctacattcaaaccaa
gtgatacaccgagatattaagagtgacaatatcctcctggggatggacggagctgtgaaa
ctgactgactttgggttctgcgcacagatttcacctgaacagaataagcgcagtactatg
gtgggcacgccatattggatggctcctgaagtggtgacccggaaagcctacgggcctaaa
gtggatgtatggtctctggggatcatggctattgaaatggtggagggggagcctccttac
ttgaatgaaaatcctctcagggcgctgtaccttattgctaccaatggaaccccacagctg
caggagccagagaagaagtcgccggcattcagagacttcctgagccgctgccttgagatg
gatgtagaaaaaagaggctcggccagggatctcctccagcacccgttcctgaaggttgcc
aaacctatgtcgagcctcacgccgtacataattacaggaaagcagatggcaaaaggcggt
ctgtga

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