KEGG   Xenopus tropicalis (tropical clawed frog): 100486097
Entry
100486097         CDS       T01011                                 
Symbol
tph2
Name
(RefSeq) tryptophan 5-hydroxylase 2
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00380  Tryptophan metabolism
xtr00790  Folate biosynthesis
xtr01100  Metabolic pathways
Module
xtr_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    100486097 (tph2)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100486097 (tph2)
Enzymes [BR:xtr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     100486097 (tph2)
SSDB
Motif
Pfam: Biopterin_H
Other DBs
NCBI-GeneID: 100486097
NCBI-ProteinID: XP_002940217
Xenbase: XB-GENE-958329
UniProt: A0A8J0QWL5
LinkDB
Position
3:60065515..60163459
AA seq 485 aa
MQPAMMMFSSKYWARRGMSLDSAMSQDFLNAPSRDKLNVLRIDENKCSKTEATAETERTA
VILTMKNEVGGLLQNLKIFKEKYVNIIHIESRKSKGNKSEVDMYVEFECTKKKCQELQHL
LKLQSGIISVNPVERIWRKDEELEGVLWFPRKISELDKCSNRVLMYGSELDADHPGFKDN
VYRQRRKYFVDVAMDYKYGQPIPRVEYTAEEIKTWGTVFKELTKLYPTHACKEYLKNLPL
LTKYCGYREDNVPQLEDVAIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHG
SDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFG
LCKQDGQLRAYGAGLLSSIGELKHALSDKAIVKTFDPKTTCLQECIITTFQDSYFVSESF
DEAKEKMREFAKSINRPFSVYFNPYTQSIEILNNTRSIENVIQDLRSDLNTVSDALAKMN
KYLGI
NT seq 1458 nt   +upstreamnt  +downstreamnt
atgcaacctgcaatgatgatgttctcgtccaaatactgggccaggagggggatgtcattg
gactctgcaatgtcccaggacttcctaaatgcaccctcgagagacaaactaaatgttttg
agaattgatgagaataaatgtagcaagactgaagccactgcggaaacagagaggacggca
gtgatacttacaatgaaaaatgaagttgggggattactgcaaaatctaaaaattttcaag
gaaaagtatgtgaatattattcacatagaatcacggaaatctaaggggaacaagtctgag
gtggacatgtatgtggaatttgaatgtaccaagaaaaaatgccaagaactccaacatctg
ctgaaactccaaagcggcatcatatccgtaaatccagttgagaggatctggaggaaggat
gaagagctggaaggagttttgtggtttcccaggaagatctctgaactagataaatgctcc
aacagagtcttgatgtatggatctgaactggatgctgaccatcctggatttaaggacaac
gtgtacagacaaagaagaaagtattttgtagatgtggccatggactataaatatggccaa
cccatacctagagtggagtacacagcagaagagataaaaacatggggcactgtatttaag
gaacttaccaaattatacccaacacatgcctgcaaagagtacctcaagaaccttccactg
ttaaccaaatattgtggctaccgagaagataatgttccacaacttgaggatgttgctata
tttctcaaagaaagatctggcttcacggtgagacctgttgcgggctatctatcacctaga
gactttttagctggcttagcctaccgggtttttcactgcacgcagtacattaggcacgga
tcagatcccctctacacacctgagccggacacatgccatgaattgctgggccatgttcct
ttgcttgcggaccccaaatttgcccagttttcacaggagattggtcttgcttccttgggt
gcatccgatgaagatgttcagaaacttgcaacttgttatttctttacaattgagtttggc
ctctgcaaacaagatggacagctacgtgcatatggagcaggacttctgtcttctataggg
gaattaaagcacgccttgtctgacaaagctattgtgaaaacgtttgatccaaagacaacc
tgcttacaagaatgtattatcaccacctttcaggattcctactttgtgtcagaaagcttt
gatgaagccaaggaaaaaatgagggaattcgccaaatcaatcaacagacctttttcagtc
tacttcaatccttatactcagagcattgaaatccttaacaatacccggagtattgaaaat
gtcattcaagatttacggagtgatctaaacacagtgtctgatgctttagccaaaatgaat
aaatatttgggaatataa

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