Xenopus tropicalis (tropical clawed frog): 448586
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Entry
448586 CDS
T01011
Symbol
srd5a1
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 1
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00140
Steroid hormone biosynthesis
xtr01100
Metabolic pathways
Module
xtr_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
xtr_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
448586 (srd5a1)
Enzymes [BR:
xtr01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
448586 (srd5a1)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
448586
NCBI-ProteinID:
NP_001006841
Xenbase:
XB-GENE-1000046
UniProt:
Q6DF23
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Position
6:78270031..78276118
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AA seq
257 aa
AA seq
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MSLSALVGDEAQLLNLLAMFMALMGLVSYVSLQYIRMPYGRYADSAFGPPVPVRLAWFVQ
EVPSLSVSLFFYLRQTEFSIANQVLMGAFICHYTQRTLIFPFLIRGGKPTPFASFALAFI
FCCYNGYLQSSYLCSHAAYASDWIHDPRFITGIMLFFCGMFINIYSDRILRNLRKPGEMG
YKIPKGGLFDYVSGANFFGEIVEWSGFALAGWSLPAAAFAIFTAFVLTSRAQQHHKWYLE
KFEDYPKNRKILVPFLY
NT seq
774 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctgtcagcactggttggagatgaagcgcagttattgaacctgttggctatgttt
atggctcttatgggtctggtctcctatgtctcgctgcagtacatccgaatgccttacggt
cgctatgccgactcggcgtttgggccgccagtaccagtgcgcttggcatggtttgtccag
gaagtgccgtcattgtctgtttccttgttcttttatttaagacaaaccgaattcagcatc
gccaatcaggtgctaatgggagcctttatttgtcattatactcaaaggacccttatattt
ccattcctaattagagggggaaagcctacaccatttgcatcatttgcacttgccttcatc
ttttgctgttacaatgggtacctgcagagcagctacctgtgcagtcatgctgcctatgcc
tcagactggatccatgaccctcgctttataacaggaataatgttgtttttctgtggcatg
tttatcaatatctattctgatcgcattctaaggaatttgcgtaaacctggtgaaatggga
tacaaaattcccaaaggaggattatttgattatgtgtctggagcaaacttttttggtgaa
atagttgaatggtctggctttgcattagctgggtggtcccttcctgcggctgcatttgca
atctttacagcatttgtcctgacttccagggcacaacagcatcacaaatggtaccttgaa
aaatttgaagattatccaaaaaacagaaaaatacttgtaccatttttatattaa
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