Xenopus tropicalis (tropical clawed frog): 496490
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Entry
496490 CDS
T01011
Symbol
akr1c4
Name
(RefSeq) aldo-keto reductase family 1, member C4
KO
K00037
3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:
1.1.1.50
1.1.1.357
1.1.1.225
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00120
Primary bile acid biosynthesis
xtr00140
Steroid hormone biosynthesis
xtr01100
Metabolic pathways
Module
xtr_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
496490 (akr1c4)
00140 Steroid hormone biosynthesis
496490 (akr1c4)
Enzymes [BR:
xtr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
496490 (akr1c4)
1.1.1.225 chlordecone reductase
496490 (akr1c4)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
496490 (akr1c4)
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Motif
Pfam:
Aldo_ket_red
Motif
Other DBs
NCBI-GeneID:
496490
NCBI-ProteinID:
NP_001011079
Xenbase:
XB-GENE-5895888
UniProt:
Q5XGH3
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Position
3:complement(7642684..7663738)
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AA seq
320 aa
AA seq
DB search
MFLTKDTRLTLHDGNAIPVMGLGTYASAEVPKSDGTEATKLAIDLGYRHIDCAYIYGNEV
QIGEAIRSKIADGTVKREEIFYTGKLWCSFFSPNLVRQGLEASLKALQLDYLDLFIMHWP
FSVKPSDAHSNQPLDFDDVDFCLTWEALEGCKDAGLVKSIGVSNFNRRQLERLLNKPGLK
YKPVCNQVEYHVYLNQSKLHEYCKCHNIVLVAYSVLGTARDNTWVDPNSPVLLEDPVLRS
VAAKYNRSPAEVAMRFILQKGAVVLAKSFNPTRLKQNLGVFEFELKPEDMEMLDGLNRNL
RYAQFTVMKQHPEYPFHDEY
NT seq
963 nt
NT seq
+upstream
nt +downstream
nt
atgtttcttaccaaagatacccgccttaccctacacgatggaaatgccataccagttatg
ggcctgggaacgtatgcctctgctgaggtacccaaaagtgatgggacggaggccaccaag
ctcgcaatagatctgggctaccgccacattgactgtgcctatatctatggcaatgaggtc
caaattggtgaggccattcgctcaaagattgccgacggcacggtgaagagagaggagata
ttctacactgggaagctttggtgctcattcttctctccgaatttggtgcgtcagggactg
gaggcatcgctgaaggctctgcaactggattacctggacctgtttataatgcactggcca
ttctcagtaaagccctcagatgcccacagcaaccaacccttagactttgatgatgtggac
ttttgtttgacttgggaggcactagaggggtgcaaagacgcaggactggtgaagtccatc
ggggtgtccaacttcaatcgtaggcaactggagcggctcctcaacaaaccagggctgaaa
tataaacctgtctgcaaccaggtggaataccatgtgtatctgaatcagagcaaactccat
gaatattgcaaatgccacaatatcgttctggtggcctacagtgtcctgggaaccgccaga
gacaatacttgggtggatccaaactccccggtcctgttggaagacccagtgctcaggagt
gtggctgcgaaatacaatagatctcctgccgaggtggccatgcgcttcatcctccagaaa
ggagccgttgtattggccaaaagctttaaccccactcgcctgaagcagaacctgggggta
tttgagtttgagctgaagcctgaagatatggaaatgcttgatggactcaataggaacctg
cgctatgcacagtttacagtaatgaagcagcacccagaatatccgtttcatgatgagtat
tga
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