Xenopus tropicalis (tropical clawed frog): 733890
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Entry
733890 CDS
T01011
Symbol
ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X4
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04012
ErbB signaling pathway
xtr04148
Efferocytosis
xtr04370
VEGF signaling pathway
xtr04510
Focal adhesion
xtr04810
Regulation of actin cytoskeleton
xtr05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
733890 (ptk2)
04370 VEGF signaling pathway
733890 (ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
733890 (ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
733890 (ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
733890 (ptk2)
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
733890 (ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xtr01001
]
733890 (ptk2)
01009 Protein phosphatases and associated proteins [BR:
xtr01009
]
733890 (ptk2)
Enzymes [BR:
xtr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
733890 (ptk2)
Protein kinases [BR:
xtr01001
]
Non-receptor tyrosine kinases
FAK family
733890 (ptk2)
Protein phosphatases and associated proteins [BR:
xtr01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
733890 (ptk2)
BRITE hierarchy
SSDB
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
FERM_F2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
733890
NCBI-ProteinID:
XP_002934523
Xenbase:
XB-GENE-952025
UniProt:
F7CW18
LinkDB
All DBs
Position
6:complement(146579974..146731136)
Genome browser
AA seq
1125 aa
AA seq
DB search
MWLEGAGRLGPERPGAVIFMEKSGCSPFPICWAKEYDRHLASGKAMAAAYLDPNLNHTPS
TNAKSRLSTGMERSPGAIERVLRVFHYFESNNEPTTWSSNIRHGDATDVRGIIQKIVDSH
KVKNVASFGLRLSHLHSEEVHWLHPDMGVSHVREKYEQSHPPEEWKYELRIRYLPKGFLN
QFTEDKPTLNFFYQQVKNDYMSEIADQVDQEIALKLGCLEIRRSYGEMRGNALEKKSNYE
VLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRYDK
ECFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFTQVQTIQYSSSEEKDRKGM
LQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVSGASESFIIRPQKEGERALPSIPK
LANSEKHGVRAHAVSVSDEFSGDETDDYAEIIDEEDTYTMPSTEVVSFFMTGILESYGLD
EAGDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQ
EALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQL
STALAYLESKRFVHRDIAARNVLVSSSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMA
PESINFRRFTSASDVWMFGVCMWEILMYGIKPFQGVKNNDVIGRIENGERLPMPPNCPPT
LYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMRMESRRQVTVSWDSGGSDE
APPKPSRPGYPSPRSSEGFFPSPQHMVQPNHYQVSGFSISHGIPSMSGNLYPGQASVIDH
MDSWNHRTPDINMWQPGMEDSGPMDLRSMAQVLPTHLMEERLIRQQQEMEEDQRWLEKEE
RFLKPDVRLSRGSVDHVDGNLQCPAGNQHIYQPVGKPDHSAPPKKPPRPGAPSHLGNLPA
HNSPVDSYNEGVKPWRIQPQEISPPPTANLDRTNDKVYENVTGLVKAVIEMSSRIQPAPP
EEYVPMVKGVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLAELINKMKLAQQY
VMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRMISHSRPH
NT seq
3378 nt
NT seq
+upstream
nt +downstream
nt
atgtggttggaaggggcaggccggctgggcccggagcggccaggtgctgtcatctttatg
gagaagagcggatgcagtcccttcccgatctgctgggccaaagaatatgacagacaccta
gcatccggcaaggctatggctgcggcttacctggacccaaacctaaaccacactccgagc
acaaacgccaagtcccgcctaagcacaggcatggagcgctctccaggagccatcgaaaga
gtcttaagggtcttccactactttgaaagcaacaatgaaccaacgacatggtctagcaat
atccgacacggggacgcaacagatgtcaggggaatcatccagaagattgttgacagtcac
aaagtaaagaacgtggcttccttcgggctcaggctcagtcacttgcactcagaggaggtt
cactggttgcacccggacatgggggtgtcacatgttagagagaaatatgaacagtcccat
ccgccggaagaatggaagtacgagcttagaattcgatatctgccgaaaggatttctgaat
cagttcacagaagacaaacccaccctgaatttcttttatcagcaggtaaaaaatgattat
atgtcagaaatagccgaccaagtggaccaagagattgccttgaaattgggctgtctggaa
attaggagatcctacggggagatgaggggcaatgcccttgaaaagaaatccaactatgaa
gttttagagaaagacgtgggcctgaagaggttttttccaaagagtttactggattcggtg
aaggcaaaaaccctaagaaagttgattcaacagacttttcggcagtttgccaacttgaac
cgagaagaaagtattttgaaattctttgaaattctctctccggtgtacagatacgacaag
gaatgcttcaagtgcgccctcggatccagttggattatatccgtggagttggctattggc
ccagaagaagggattagttacctcacagacaagggctctaatcccacccatctggcagac
tttactcaggtccaaacaatccagtattccagcagtgaagagaaggacagaaaggggatg
ttgcagttgaaaattgctggagccccagagcctctgactgtgacagccccgtccctcacc
atcgctgagaacatggcggacttgatagatggatactgtcgcctcgtcagcggagcctcg
gaatcttttatcatccggccacaaaaagaaggcgagagagcgcttccatccataccaaag
ctggccaacagcgagaagcatggggtccgggcgcacgcagtctccgtatcagatgaattt
agtggggacgagactgacgactatgcagaaattatagatgaagaggacacatacactatg
ccttccacagaagtagtgtctttctttatgacaggaattctagagagctatggattagac
gaagctggcgattatgagatccagagagagcgcattgagctgggacgctgcattggtgaa
gggcagtttggagatgttcaccaaggggtttacatgagtccggagaatccggccatggct
gtcgcaatcaaaacgtgtaagaactgcacatcggacagtgtgagagaaaagttcttacaa
gaggccttaactatgcgccagtttgaccacccgcacattgtgaagttaattggagtcatt
acggagaacccagtctggattatcatggaactgtgcaccctgggagagctgagatcattt
ttacaagtcagaaaatacagtctggatctggcatccttgatcctctacgcttaccagctc
agcacggcgctcgcctacttggaaagcaaacgatttgtacatagagatattgctgctaga
aatgtactggtctcgtcctcggactgtgtaaaattaggggactttggcctctccagatat
atggaggacagtacttactataaagcttccaaaggcaaattgcccattaaatggatggcg
ccggagtccattaactttagacgttttacctctgccagtgacgtgtggatgtttggtgtg
tgcatgtgggaaatattaatgtatggaatcaagcctttccaaggggtaaagaacaacgat
gtgattggtcgaattgagaatggtgaacgcttgccgatgccccccaactgcccccccacg
ctgtacagccttatgacgaagtgctgggcctacgacccaagtaggaggccgcgatttact
gaactcaaagcacaactcagtactatactggaagaggagaagttgcagcaggaggagcgg
atgaggatggaatcccgccgacaggtgacggtttcctgggattcgggaggatccgacgag
gcccccccaaagcccagcaggccgggataccccagcccgaggtccagcgaaggttttttc
ccaagtcctcaacacatggtgcagcccaatcactaccaggtttctggcttttccatttcc
catgggattccctccatgtcaggaaacctgtatccaggtcaggcatccgttatagatcac
atggattcctggaaccaccggacacctgatataaacatgtggcagcccggcatggaggac
tctgggcccatggacctgaggagtatggcccaggttctgccgacccatttaatggaggaa
aggctaataaggcagcagcaagagatggaggaagatcaacgctggctggagaaggaggag
agatttttgaagccagatgtgcggctctccaggggcagcgttgaccacgtggatggaaac
cttcagtgcccagctgggaaccagcacatataccaacctgttggaaagccggatcactcg
gctccaccaaagaaacctccgcgccctggggcccccagccacctggggaaccttcctgca
cacaacagcccggtggacagctacaatgaaggcgtcaagccatggcggatccagccccag
gagatcagccccccgccgactgccaacctggaccgaaccaacgacaaagtctacgagaat
gtgaccggtctggttaaagctgtgatagaaatgtcgagcaggatccagccggcgcccccc
gaggaatatgttcccatggtcaagggggtgggcctggcgctgcggacgttattggcgaca
gtagatgaaaccattcctgttcttccggccagcactcacagagagatcgagatggcgcag
aagctgctgaattcggacctggcggagctgatcaataagatgaagttggcgcagcagtac
gtgatgaccagcctgcagcaggagtacaagaagcagatgctgacggcggcgcacgctttg
gccgtagacgccaagaacttgctcgatgtcatagaccaagcgcgactgagaatgatcagc
cactcgcggccgcattag
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