Xenopus tropicalis (tropical clawed frog): 780194
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Entry
780194 CDS
T01011
Symbol
itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04120
Ubiquitin mediated proteolysis
xtr04144
Endocytosis
xtr04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
780194 (itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
780194 (itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
780194 (itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
xtr04131
]
780194 (itch)
04121 Ubiquitin system [BR:
xtr04121
]
780194 (itch)
Enzymes [BR:
xtr01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
780194 (itch)
Membrane trafficking [BR:
xtr04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
780194 (itch)
Ubiquitin system [BR:
xtr04121
]
Ubiquitin ligases (E3)
HECT type E3
780194 (itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
WW_TCERG1
Motif
Other DBs
NCBI-GeneID:
780194
NCBI-ProteinID:
NP_001072737
Xenbase:
XB-GENE-976485
UniProt:
A0JM32
LinkDB
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Position
10:complement(41192426..41224958)
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AA seq
853 aa
AA seq
DB search
MDGSGSRPGAVNGFTMKSQLQVIVISAKLKDNRKNWFGPSPYVELSVDGQSKKTETKNKT
HSPKWKQPLTVIVTPFSVLNFRVWSHQTLKSDALIGSASLNLHETLLSNNMKLEEVIVTM
QLLSDRETVGDLSVCLDGMQVDPELLANGDPAVSSGSTDNSSTEVESQAASAESSNGTNS
TDSRTTNGMSSPSLANGGFKASRPPRPSRPPPPTPRRASGVVTAISEAPPPPEAELLPTP
ATASLPEAQAPSSTPPVSRQIAPINVDGQRMGLVNQGPLPPGWEQRVDQQGRVYYVDHVA
KRTTWDRPEPLPPGWERRVDNMGRIYYVDHITRTTTWQRPTLESVRNYEQWQLQRNQLQG
AMQQFNQRFIYGTQETGTTQNKEYDPLGPLPVGWEKRMDGNGRVYFVNHTTRTTQWEDPR
NQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRKTTTYIDPRTGKSALDNGPHIAYVRDFKA
KVQYFRFWCQQLYMPQHVKITVNRKTLFEDSFQQIMSFNAQDLRRRLWIIIPGEEGLDYG
GVAREWFFLLSHEVMNPMYCLFEYAGKDNYCLQINPASYINPDHLRYFRFIGRFIAMALF
HGKFIDTGFSLPFYKRILNKPVGLKDLESVDPEFYNSLIWIKDNNIEECGLEMFFSVDKE
ILGDVKSHDLKPDGSNIQVTEENKEEYIRLVAEWRLSRGVEEQTQAFFEGFNEILPQQYL
QYFDAKELEVLLCGMQEIDLNDWQRNTIYRHYTRTSKQIIWFWQFVKEIDNEKRMRLLQF
VTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKL
LFAIEETEGFGQE
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atggatggcagtggttcaagaccaggagcagtcaatggcttcacaatgaaatcacagctt
caggttatagttatatccgctaagttaaaggacaacaggaaaaactggtttggtccaagt
ccgtatgtggagctgtcggtggatggacaatcaaagaaaactgaaacaaaaaataaaact
cacagccccaaatggaaacagccgctcactgtcattgttaccccatttagtgtgttaaat
ttccgcgtttggagccaccagacgttgaaatccgatgctctgattggaagcgcgtcgctc
aacttgcatgaaacgctactgtcgaacaatatgaagttggaagaagtcattgtgaccatg
cagctcttaagtgacagggagacggtgggcgacctgtctgtgtgcttggatgggatgcag
gtggacccggagctcttagccaatggagatccagctgtctcatcaggttcaacagataat
tcctcgactgaagttgaatcacaggctgcgagtgctgaaagctcaaatggaactaattcc
actgacagcagaacaaccaatggcatgagctctccttccttagccaatggagggtttaaa
gccagcagaccacctagaccatcacggcctcctccccccacacctcgcagggcgtctggt
gtagttactgccatcagtgaagctcccccaccaccagaggctgaattgttgcccacccct
gctactgcttccttacctgaagcccaagctccatccagtacgcctcctgtttctaggcaa
atagctcccattaatgttgatggacagagaatgggactagttaaccaaggacctctgcca
cctggatgggaacagcgggtggatcagcaaggacgcgtttattatgtggatcacgtggca
aaaagaactacatgggacaggccagaacccctgccacctgggtgggaacgtcgagtggat
aacatgggtcggatctattatgtggaccatataacccggaccactacatggcagcgcccc
actcttgagtctgtgcggaattatgagcagtggcagctccagcggaaccagctacaaggc
gccatgcagcagttcaaccaaaggtttatttatgggacccaggaaactggaacaacccag
aacaaggagtatgacccattaggaccattaccagttggatgggaaaagcgtatggatgga
aatgggcgagtgtattttgttaatcacaccacacggaccacccagtgggaggacccaaga
aatcagggacagttgaacgagaagccattgccagagggttgggagatgaggtttacggta
gatggcatcccatattttgtggatcacaacaggaaaaccaccacttacatcgaccctcgg
actggcaaatcagctctggacaatggacctcatatcgcttatgtgcgggattttaaggct
aaggtccaatacttcagattctggtgccagcaactttacatgcctcagcatgtcaagatc
actgtgaacaggaaaacactttttgaagactcatttcagcagattatgagtttcaacgca
caagatctcaggagaagactgtggattatcatccctggggaagagggcttggattacgga
ggagtggcaagagagtggttcttcctcctctctcacgaagtaatgaatcccatgtactgc
ctatttgaatacgccgggaaggataactactgtctgcaaatcaaccctgcttcctacatc
aacccagaccacctgcgctacttccgtttcatcggcaggttcatagccatggccctgttt
catggcaaatttatagacacgggtttttctttgcctttttacaaacgaatcttaaataaa
ccggtgggtcttaaagatctggaatccgtggatcctgaattctacaattcactcatttgg
ataaaggacaacaacattgaggagtgtggcctagagatgtttttctccgtggacaaagaa
attttgggggatgtcaaaagccacgatctgaaaccagacggcagtaacatccaagtgacg
gaagagaacaaggaagagtatatccggctggttgcagagtggagactctcccggggagta
gaggaacagacacaggctttctttgagggtttcaatgagattctcccacaacaatacttg
caatactttgatgccaaggagttagaggtgctcctgtgtgggatgcaggaaattgatctg
aatgattggcaacgtaacaccatctaccggcactataccaggaccagcaagcaaatcatt
tggttctggcagtttgttaaagaaattgataatgagaagcgaatgagacttctacagttt
gtgactggcacctgcaggttacctgtagggggattcgctgatctcatgggaagcaacggg
cctcagaaattctgtattgagaaggttggtaaagaaaactggcttcccaggagtcataca
tgctttaaccgtctggatcttccaccctacaaaagctacgagcagctgaaggagaaacta
ctgttcgctatagaggagacagaaggttttgggcaggagtaa
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