Yarrowia lipolytica: 2905745
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Entry
2905745 CDS
T01033
Symbol
YALI2_A00250g
Name
(RefSeq) Histidine biosynthesis trifunctional protein
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
yli
Yarrowia lipolytica
Pathway
yli00340
Histidine metabolism
yli01100
Metabolic pathways
yli01110
Biosynthesis of secondary metabolites
yli01230
Biosynthesis of amino acids
Module
yli_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
yli00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
2905745 (YALI2_A00250g)
Enzymes [BR:
yli01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
2905745 (YALI2_A00250g)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
2905745 (YALI2_A00250g)
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
2905745 (YALI2_A00250g)
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Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
DUF6823
Motif
Other DBs
NCBI-GeneID:
2905745
NCBI-ProteinID:
XP_500110
UniProt:
A0A1H6Q1S9
Q6CGV2
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Position
A:1646316..1648883
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AA seq
855 aa
AA seq
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MFPLLPQVSSVTVPAVAVAPGKVLVSILQSDVPEIAKELKKAFGQAQFHIMADTDLSTDE
YIHLLDAGASSVFVSGESAVDLAASGVPAGRLTVIGSKPDNLDVGGVFLKDTPALEDVAT
LASTFAKQLLPSGGAPVVYVNVEDPKAAADLAATGATVVVSSAKLTTEHQADKLDDKFPI
ADLLLASLSTDRQDGLYTTLVTDVLNQSLGLVYSSAESIKEAIRTGTGVYQSRRHGLWYK
GKESGNTQKLIRIETDCDGDCLKFIVEQTGAGFCHFNTESCFSAAQGISCLEKTLQQRLQ
NAPAGSYTKRLFDDSDLLRAKIMEEAEELVEAKDAEEVSWEAADLIYFAMVKVVKEGVSW
AQVMNNLDSKHMKISRRKGDAKQKWVDALGIKRQKVDEKPKEEKKEEKKEEIKEDGKIQL
NHINADTASKAEIETVLARPAQKTSDIMKLVLPIVEGVKTGGDKKLLELTEKFDGVKLES
PILTAPFSEDLMKISDDVKASIDMSIANVKKFHAAQLDTTELVVETQPGVVCKRFSRPIE
SVGLYIPGGTAVLPSTSLHLGVPAMVAGCKNIVLASPPRKDGTLSPEVVYVAHQIGAKAV
VLAGGAQAVAAMAYGTESVPKVDKIMGPGNQFVTAAKMYVSNDTTAKVAIDMPAGPSEVL
VICDKHANPAFVASDLLSQAEHGVDSQVILLAVDCDQKHLDAIDEELHAQALALPRVDII
RKCIAHSSALSVKTMDEAFKLSNQYAPEHLILQIEDADKYVPLVDHAGSIFVGAYSPESC
GDYSSGTNHTLPTYGYARMYSGVNTGTFTKHITSQQLTREGLEIIGPAVMTLAATEGLDA
HRMAVKVRLDAMKKE
NT seq
2568 nt
NT seq
+upstream
nt +downstream
nt
atgttccccctgctgccccaagtgagcagcgtgactgttccggctgtggctgtggcgccc
ggcaaggtgctggtgtccattctccagtccgacgtccccgagatcgccaaggagctcaaa
aaggcgtttggacaggcccaatttcacatcatggccgacacagacctgtcgaccgacgag
tacatccacctgctggacgccggcgcctcgtctgtgtttgtgtctggagagtccgctgtt
gatctggctgcctccggcgtgcctgctggccgtctgacagtgattggctccaagcccgac
aacctggacgtcggcggcgtcttcctcaaggacacccccgctctggaggatgtggcgacg
ctggcctcgaccttcgccaagcagctgctgccctcgggaggagccccggttgtgtatgtc
aacgtggaggatcccaaggccgcggctgatctggctgcaaccggcgccactgtggtggtg
agctccgctaagctgaccaccgaacaccaggccgacaagctggacgacaagttccccatt
gccgatctgctgttggcgtctctgtccaccgaccgacaggacggcctgtacactactctg
gtgaccgatgtgctcaaccagtcgctcggcctcgtctactcgtcggctgagtccatcaag
gaggccattcgaaccggcactggtgtttatcagtcccgacgacacggtctgtggtacaag
ggtaaggagtctggaaacacccagaagctgatccgaattgagactgactgcgatggagac
tgtctcaagttcatcgttgagcagaccggcgcgggcttctgccacttcaacaccgagagc
tgtttctccgctgcccagggcatttcttgtctggagaagacccttcagcagcggctgcaa
aatgcccccgcaggttcgtacacaaagcgactttttgacgactcggatctgctgcgagcc
aagatcatggaggaggctgaggagctcgtggaagccaaggacgccgaggaggtgtcttgg
gaggctgccgacctcatctactttgccatggtcaaggttgtcaaggaaggcgtgagctgg
gcccaggtgatgaacaacctcgacagcaagcatatgaagatttcgcgacgaaagggcgac
gccaagcaaaagtgggtcgacgctctgggaatcaagcgacagaaggtggacgagaagccc
aaggaggagaagaaggaagagaagaaggaggagatcaaggaggacggcaagatccagctc
aaccacatcaatgctgataccgcctccaaggccgagattgagactgttctggcccgacct
gctcagaagacctctgatatcatgaagcttgtgcttcccattgttgagggagtcaagact
ggaggcgacaagaagctgctggagctgaccgagaagtttgacggtgtcaagctcgagtct
cctattctcactgctcctttctccgaggacctgatgaagatttccgatgatgttaaggct
tccattgacatgtccattgcgaacgtcaagaagttccacgctgcccagcttgacaccacc
gagcttgtggttgagacccagcccggtgtggtctgcaagcgattttctcgacccattgag
agtgtcggtctgtacattcctggtggaactgcagttcttccttccacctctctgcatctc
ggtgtccctgccatggttgctggatgcaagaatattgttctggcctcccctccccgaaaa
gacggcactctttcccccgaggttgtctacgttgctcaccagattggcgccaaggccgtt
gttcttgctggaggcgcccaggccgtcgctgctatggcttacggaaccgagtccgtgccc
aaggttgacaagatcatgggtcctggaaaccagtttgtcaccgccgccaagatgtacgtg
tccaacgacaccactgccaaggtggctatcgacatgcccgccggcccctctgaggtgctt
gtgatctgcgacaagcacgccaaccctgcctttgttgcctccgatctgctttctcaggcc
gagcacggcgttgattcccaggtcattctgctggctgtggactgcgaccagaagcacctt
gatgccattgatgaggagctgcatgctcaggctcttgctcttcctcgagtcgacattatc
cgaaagtgtattgcccactcttctgctcttagcgtcaagaccatggacgaggccttcaag
ctgtccaaccagtacgcccccgagcatctgattctgcagattgaggatgccgacaagtac
gtgcctctggtggaccacgctggttccattttcgtcggagcttactctcccgagtcttgt
ggagactactcttccggaaccaaccacactctgcccacctacggatacgcccgaatgtac
tctggcgtgaacaccggcaccttcaccaagcacattacgtcgcagcagctgacccgggag
ggtctggagatcattggtcccgccgttatgactcttgctgccaccgagggtctggacgcc
caccgaatggccgtcaaggtccgactcgacgccatgaagaaggaataa
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