Yersinia pestis Harbin 35 (biovar Medievalis): YPC_0027
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Entry
YPC_0027 CDS
T01874
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
yph
Yersinia pestis Harbin 35 (biovar Medievalis)
Pathway
yph00270
Cysteine and methionine metabolism
yph00450
Selenocompound metabolism
yph00670
One carbon pool by folate
yph01100
Metabolic pathways
yph01110
Biosynthesis of secondary metabolites
yph01230
Biosynthesis of amino acids
yph04981
Folate transport and metabolism
Module
yph_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
yph00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
YPC_0027 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
YPC_0027 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
YPC_0027 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
YPC_0027 (metH)
04980 Cobalamin transport and metabolism
YPC_0027 (metH)
Enzymes [BR:
yph01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
YPC_0027 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ADV96800
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All DBs
Position
25855..29547
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AA seq
1230 aa
AA seq
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MDTVIDNKVKELHQQLAQRILVLDGGMGTMIQSYRLEEADYRGARFADWASDLKGNNDLL
VLSKPEVITAIHNAYLEAGADILETNTFNSTSIAMADYQMASLSAEINYEAARLARICAD
EWSARTPEKPRYVAGVLGPTNRTASISPKVNDPAFRNVSFDQLVEAYRESTRALIEGGVD
LIMIETVFDTLNAKAATFAVESEFEVMGVLLPVMISGTITDASGRTLSGQTTEAFYNSLR
HVKPLSFGLNCALGPDELRQYVAELSRISEYYVSAHPNAGLPNAFGEYDLEAKEMAEQIG
EWARAGFLNIVGGCCGTTPRHIAAMVNAVAGVPPRPLPDIPVACRLAGLEPLTIDANTLF
VNVGERTNVTGSARFKRLIKEEKYGEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRF
LNLIAGEPDIARVPIMIDSSRWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLVRRY
GAAMVVMAFDETGQADTRARKIEICRRAYKILTETVGFPPEDIIFDPNIFAVATGIEEHN
NYAVDFIEACADIKAELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGI
VNAGQLAIYDDLSDELRDAVEDVILNRRDDSTERLLDLAEKYRDSKSGEVAIQQAEWRGW
PVVKRLEYSLVKGITEFIELDTEEARQQADRPIEVIEGPLMSGMNVVGDLFGEGKMFLPQ
VVKSARVMKQAVAYLEPYIEASKQKGTTAGKILLATVKGDVHDIGKNIVGVVLQCNNYEI
IDLGVMVPTEKILRTAREEKVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATT
SKAHTAVKIEQNYSGSTTYVSNASRSVGVVSALLSDTQREAFVAKTRKEYETVRIQHARK
KPRTPPVSLQAARNNPTVIDWENYTPPVAHKLGVQVVEASIETLRNYIDWTPFFMTWSLA
GKYPRILEDEVVGEEAKRLLADANALLDKLSAEDLLHPKGVVGLFPANSVGDDIEIYRDE
RRDEVLAISYHLRQQTEKTDFPNYCLADYVAPKSSGKADYFGAFAVTGGLEEDALADAYD
AQHDDYNKIMIKALSDRLAEAFAEYLHERVRKVYWGFAPNENLSNEELVRENYQGIRPAP
GYPACPEHTEKGQIWQLLDVETHTGMKLTESYAMWPGASVSGWYFSHPDSKYFAVAQIQR
DQVEDYAARKGMPTAEVERWLAPNLGYDAD
NT seq
3693 nt
NT seq
+upstream
nt +downstream
nt
gtggatacagtaatcgataataaggtcaaggaattgcaccagcagttggcgcaacgcatt
ttggtactggatggtggtatgggcaccatgatccagagctaccgattagaagaagcagat
taccgaggcgcgcgttttgctgactgggcaagtgacctaaaaggtaacaatgacctcttg
gtgctctccaagccagaagtcatcacggcgatccataatgcctaccttgaagccggtgct
gacattctcgaaaccaatacctttaactctacctccattgcgatggcggactatcagatg
gcgtcactgtcggctgaaattaactatgaagccgcccgtctggcccgtatctgtgccgat
gaatggagcgcccgcacgccagaaaaaccacgttatgttgccggggtgctggggccaacc
aaccgtactgcctccatctcccctaaagttaatgacccggcgttccgtaacgtcagtttt
gatcagttggtcgaggcctatcgtgagtctacccgcgcgctgattgaagggggtgttgat
ttaattatgatcgaaacggtcttcgatacgttgaatgcgaaggccgcgacctttgcggtt
gaaagcgaattcgaagtgatgggcgtgctgttgccggtgatgatttccggcaccattacc
gatgcctccggccgtacgctgtctggtcaaacgacggaagctttttataactcgctgcgc
catgtcaaaccgctgtcgtttggtctgaactgtgcgctggggccggatgaactgcgccaa
tatgttgctgagttatcgcgtatctctgaatattatgtcagtgcgcacccgaatgccggt
ttgccgaatgcttttggtgaatatgatctggaagccaaagagatggctgagcagattggc
gagtgggcacgtgccggatttttgaatattgtcggcggttgctgcggtaccacaccccgg
catattgcggcgatggtcaacgctgtcgctggggtgcctccgcgcccgttgcctgatatt
ccggttgcctgccgtttggccgggctggagccactgactatcgatgccaataccctgttt
gtgaacgtcggtgagcggaccaacgtcacgggttcggcacgctttaaacggctgataaaa
gaagagaagtacggagaggcgctggatgttgcccgccaacaggtcgaaagcggcgcgcag
atcatcgatatcaacatggacgaaggcatgttggatgccgaagcggccatggtgcgtttc
cttaatctgattgccggggagcctgatattgccagggtgccgattatgatcgactcctca
aggtgggatgtgattgaaaaaggcctgaaatgtattcaaggcaaaggcatcgtgaactcc
atttcgatgaaagagggcgttgatgcctttattcatcacgccaaactggtacgccgttat
ggtgccgccatggtggtcatggcctttgatgaaaccgggcaagccgatacccgcgcacgc
aaaatcgagatttgccgccgtgcgtataaaatattgacggaaaccgtcggtttcccacca
gaagatattatcttcgatccgaatatttttgccgtagcgacggggattgaagagcataac
aattatgccgtcgattttattgaagcctgtgccgatatcaaagccgagttgcctcacgcg
ctgatttctggcggtgtctccaacgtttccttctctttccgagggaatgatccagtacgt
gaagccattcatgcagtgttcctctattacgctattcgcaatggcatggatatggggatt
gttaacgccggtcaattggcgatttatgacgacctgtctgatgaattacgtgatgcggtc
gaggatgtgatcctcaaccgccgtgatgacagtactgagcgcctgctggatttagcagaa
aaataccgtgacagtaaaagtggcgaggtcgcgatccagcaagcagaatggcgtggttgg
ccggtggtgaaacggttagagtattcgctggtaaaaggcattactgaatttattgagctg
gataccgaagaagcgcgccagcaggcagatcggccaattgaagtgattgaagggccgtta
atgtctgggatgaatgtggttggtgacttgtttggtgaaggaaaaatgttcctgccacag
gttgtaaaatcagccagggtaatgaaacaggcggtggcctatctcgaaccttatattgaa
gccagtaagcagaagggtaccaccgccggtaaaatcttattagcaaccgtcaaaggcgat
gtgcatgacatcggcaagaacatcgtgggtgtggttttgcagtgtaataactatgaaatc
atcgatctgggcgtgatggtgccgacggaaaaaattctgcgcactgcacgggaagagaag
gtggatattatcggcctgtctggtctgattaccccgtcgctggacgagatggttaacgtg
gcgaaagagatggagcgccaaggctttacgctgccgttgctcattggtggcgcaacgaca
tccaaagctcacaccgcggtcaagattgaacaaaattatagcggttccaccacgtatgtc
tctaacgcctcgcgcagtgtgggcgtggtatccgcgttgctatcggatacgcaacgggag
gcatttgtggcaaaaacccgcaaagaatatgagactgtacgtatccaacacgcccgtaaa
aaaccgcgcaccccgccggtcagtttgcaggctgcacggaataacccaacggtgattgat
tgggagaactacactccgccagtggcccataaattgggggtacaggtggtggaggccagt
attgaaactctgcgcaactatatcgactggacgccattctttatgacctggtcgttggca
ggcaagtatccgcgcattttagaagatgaggtggtgggggaggaggccaagcgcctgctc
gccgacgccaatgctttgttggataaattgtccgccgaggatctgctgcatccaaaaggc
gtggttggtctgttcccggctaacagcgtcggcgatgatatcgaaatttaccgtgatgag
cggcgagatgaggtactggccatcagctatcatttacgccaacagaccgaaaaaaccgac
ttcccgaactactgtttagctgactatgtcgcgcctaaatccagtggtaaagccgattat
tttggtgcgtttgcggtgaccggtggcttggaagaagacgcattggccgatgcttatgat
gcgcaacatgatgactacaataaaatcatgattaaggcattatcagaccgtctggccgaa
gcctttgccgagtatctgcatgagcgagtacgtaaagtgtattggggttttgcaccgaac
gaaaatctgagcaacgaagagttggtgcgcgaaaattatcaggggatccgcccggcaccg
ggctatcccgcttgcccggagcacaccgagaaaggccaaatttggcagttgttggatgtc
gaaacccacaccggtatgaaactgaccgaatcctacgccatgtggcctggggcttcggta
tcgggttggtatttcagccacccagacagcaaatattttgccgtagcacaaattcagcgt
gatcaggttgaggattatgccgcccgtaaagggatgcccactgccgaagttgaacgctgg
ctagcccctaatctgggttacgatgcggattga
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