KEGG   Yersinia pestis KIM10+ (biovar Mediaevalis): y1049
Entry
y1049             CDS       T00092                                 
Symbol
acrB
Name
(GenBank) acridine efflux pump
  KO
K18138  multidrug efflux pump
Organism
ypk  Yersinia pestis KIM10+ (biovar Mediaevalis)
Pathway
ypk01501  beta-Lactam resistance
ypk01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:ypk00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    y1049 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    y1049 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ypk02000]
    y1049 (acrB)
   01504 Antimicrobial resistance genes [BR:ypk01504]
    y1049 (acrB)
Transporters [BR:ypk02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   y1049 (acrB)
Antimicrobial resistance genes [BR:ypk01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    y1049 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C MMPL
Other DBs
NCBI-ProteinID: AAM84630
UniProt: A0A3G5L7B1
LinkDB
Position
complement(1182421..1185573)
AA seq 1050 aa
MAKFFIDRPIFAWVIAIIIMLAGALAIMKLPVAQYPTIAPPAITIAANYPGADATTVQNT
VTQVIEQNMNGIDNLLYMSSSSDSSGNVQLTLTFNSGTDPDIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVAGFISEDGTMQQEDIADYVGSNIKDPISRTPGVGDVQLFGS
QYAMRIWMDPHKLNNYKLTPVDVINAIKIQNNQVAAGQLGGTPPVPGQELNSSIIAQTRL
TNAEEFSQILLKVNTDGSQVRLKDVAIVKLGAESYNIIARYNGKPAAGIGIKLATGANAL
NTSAAVKAELAKLQPFFPSGLTVVYPYDTTPFVKISINEVVKTLIEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAILSAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
QEEGLPPKEATKKSMEQIQGALVGIALVLSAVFVPMAFFGGATGAIYRQFSITIVSAMVL
SVLVALILTPALCATMLKPIKKGDHGPKTGFFGWFNNMFEKSTHHYTDSVANILRSTGRY
LVIYLAIVIGMAVLFMRLPSSFLPEEDQGVFLTMVQLPAGATQERTQKVLNHVTDYYLDK
EKNVVNSVFTVNGFGFSGQGQNTGLAFVSLKNWDERKGEQNKVPAIVSRASAAFSKIKDG
MVFAFNLPAIVELGTATGFDFQLIDQGNLGHQQLTDARNQLLGMAAQHPDMLVGVRPNGL
EDTPQFKVEVDQEKAQALGVAISDINTTLGSAMGGSYVNDFIDRGRVKKVYVQADAPFRM
LPDDIDKWYVRNNMGQMVSFATFSTAKWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAM
DLMQELAAKLPSGVGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV
MLVVPLGVVGALLAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLV
ESTLESVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMITATVLAIFF
VPLFFVVVRRRFSRKTDDIEHSHPVNTPVK
NT seq 3153 nt   +upstreamnt  +downstreamnt
atggctaagttctttatagatcgccctattttcgcttgggtcatcgccatcatcatcatg
ttggctggtgcccttgcgatcatgaaattaccagtagcgcaatatccgaccattgcgcca
ccggcaattacaattgccgccaactatcctggcgccgatgcgacaactgtgcagaataca
gtgacgcaggttatcgaacagaacatgaacggcatcgataacctgctctatatgtcttcc
agcagtgactcctccggtaacgttcagttgacgttgacctttaactctggcactgacccg
gatattgctcaggttcaggtccagaataaactgcaattagccatgccactgctgccacaa
gaagtgcagcaacagggcgtgagcgttgaaaagtccagtagtagcttcctgatggttgcc
ggttttatttctgaagacggtacgatgcagcaggaagatatcgccgactatgtgggctct
aacattaaagaccccatcagccgtacaccaggggtaggtgatgttcagttgttcggttcc
caatatgccatgcgcatctggatggacccgcataagctgaataactacaagctgacaccg
gtcgatgtgattaacgcgataaaaatacagaacaaccaggtcgctgcgggtcaattgggg
gggacaccaccagtaccaggtcaggaattgaactcatcaatcattgcacaaacccgtttg
accaatgcagaagagttcagccagatattactgaaagtgaataccgacgggtcgcaagtt
cgcttgaaagatgtggctatcgttaaactgggtgctgaaagctataacatcattgcccgt
tataacggtaaaccggccgcaggtattggtattaagctggccaccggggcgaacgccttg
aacacctctgcggcagtgaaagccgagttggccaaattacagccattcttcccatcgggg
ttgaccgtagtttatccgtatgacaccacaccatttgttaaaatttcgattaacgaagtg
gttaagacactgatcgaagccattatcttggtgttcttggtaatgtacctgttcctacag
aacttccgcgcaaccttgatcccaacgattgcggtgccggtagtgctattgggtaccttt
gctattttgtccgcctttggctattcgataaacaccttaacgatgttcgggatggtgctg
gcgatagggctattggtcgatgacgccattgtggtggtggaaaacgtcgaacgcgtgatg
caagaggagggcttaccaccgaaagaagcaaccaaaaaatccatggagcagatccagggg
gcattggttgggatcgcgttggtattgtctgcggtatttgttccgatggcttttttcggt
ggcgcaactggggctatttaccgtcagttctccattactatcgtttcggccatggtgctt
tcggttctggtggcattaattctgacaccagcactgtgtgcgaccatgctaaaaccgatc
aagaaaggcgatcatggtccaaaaactggcttctttggctggtttaacaacatgttcgaa
aagagtacacaccactataccgacagtgtcgccaatattttgcgcagcacaggccgttat
ctggttatctatctggctattgtgattggtatggcggtgcttttcatgcgtctaccgtct
tcattcctgccagaagaagatcagggggtgttcctaaccatggtgcagttgcctgcgggt
gctacgcaagaacgtacccagaaagtactgaaccatgtgacggattactatctcgacaaa
gaaaaaaacgtggttaactccgtgttcaccgttaacggctttggtttcagtggtcaaggt
cagaacaccggtttggcattcgtgagtctgaagaattgggatgagcgtaaaggcgagcaa
aataaagttccagccattgtcagccgcgcctctgctgcattctcgaaaattaaagacggt
atggtgttcgcctttaacttacccgccattgtggagttaggtacggctaccggtttcgac
ttccagttaattgatcagggtaacctggggcaccaacaattaacggatgcacgtaaccaa
ctgttgggtatggcagcgcaacatccagatatgctggttggcgtgcgccctaatgggctg
gaagatacaccacagtttaaagtggaagttgatcaggagaaagctcaagccttgggcgtt
gctatttctgacatcaataccacgctgggttcagccatgggcggcagctatgtaaacgac
tttatcgaccgaggtcgtgtgaagaaagtttatgtacaagccgatgcaccattccgtatg
ttgccggatgatatcgataagtggtatgtccgtaataatatgggtcagatggtgtcattt
gcgaccttctccaccgcgaaatgggaatatggctcaccacggctcgagcgttataatggg
ttgccatcaatggagattctgggtcaggctgcaccgggtaagagtaccggcgaagccatg
gatctgatgcaagagctggcagctaaattaccaagtggcgtaggctatgattggaccgga
atgtcctatcaggaacgtctatcgggtaatcaggccccagcactgtatgccatttcattg
attgtggtcttcttgtgcttggccgctctgtatgaaagttggtcaattccattctccgtt
atgctcgtggtaccgctcggggttgttggtgcattactggcagccacactgcgcgggttg
gaaaacgacgtttacttccaggtaggcttgctgaccaccattgggctatcggccaagaac
gccatcttgattgttgagtttgccaaagacttgatggataaagaaggcaagggcttggtg
gaatcaacattggaatcggtgcgtatgcgtctgcgcccaatattgatgacctcactggcc
tttatccttggggtaatgccactggttatcagtagtggtgccggttctggtgcacagaac
gcggtaggtaccggcgtaatgggggggatgatcactgcgaccgtactggctatcttcttt
gttccgctattcttcgttgtggttcgtcgccgcttcagcagaaagactgatgatattgaa
catagtcatccagttaacacgccggtgaaataa

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