KEGG   Yersinia pseudotuberculosis IP 32953 (serotype I): YPTB0628
Entry
YPTB0628          CDS       T00195                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase type I; trimethoprim resistance
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
yps  Yersinia pseudotuberculosis IP 32953 (serotype I)
Pathway
yps00670  One carbon pool by folate
yps00790  Folate biosynthesis
yps01100  Metabolic pathways
yps01240  Biosynthesis of cofactors
yps04981  Folate transport and metabolism
Module
yps_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:yps00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    YPTB0628 (folA)
   00670 One carbon pool by folate
    YPTB0628 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    YPTB0628 (folA)
Enzymes [BR:yps01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     YPTB0628 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: CAH19868
UniProt: Q66ER3
LinkDB
Position
746293..746775
AA seq 160 aa
MIISLIAALAADRVIGMENAMPWHLPADLAWFKRNTLNKPVIMGRKTFESIGRPLPGRLN
IVISSQPGTDERVTWAASIEEALAFAGNAEEVMVMGGGRVYKQFLDRANRMYLTHIDAEV
GGDTHFPDYEPDEWESVFSEFHDADEANSHSYCFEILERR
NT seq 483 nt   +upstreamnt  +downstreamnt
atgattatcagcctgatcgctgcattggcagcagatcgcgttattggcatggaaaacgct
atgccatggcatttaccggctgatttagcgtggttcaaacgtaacacgttaaataaaccg
gtaattatgggtcgtaagaccttcgaatctatcggtcgcccccttccgggaagactgaat
attgtcatcagtagccagcctggcactgatgaacgtgtgacgtgggcggcctcgattgaa
gaagcattggcgtttgctggcaatgcggaagaagtgatggtcatgggcggtggccgcgtc
tataagcaattcttagaccgcgcaaatcgcatgtatctcacgcatattgatgcggaggtc
ggtggcgatactcacttccctgattatgagccagatgaatgggaaagcgtattcagtgag
tttcatgatgccgatgaagctaactcacacagttattgcttcgaaattctagagcgccgc
taa

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